Book Hotels in Greenville, MO

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Greenville hotels

Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello

Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello

Wappapello MO
$230 nightly
The price is $242 total per night from Nov 3 to Nov 4
$242 total
Nov 3 - Nov 4
Total with taxes and fees
This vacation home featured laundry facilities and barbecue grills.
"Very cozy"

Reviewed on Jul 20, 2026

Opens in a new windowBrown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello
Secluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided

Secluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided

Greenville MO
Fully refundable
$262 nightly
The price is $276 total per night from Oct 12 to Oct 13
$276 total
Oct 12 - Oct 13
Total with taxes and fees
A hot tub is featured at this cabin, along with a living plant wall and barbecue grills.
"Perfect couples getaway! You will not be disappointed. Just go ahead and book it."

Reviewed on Oct 4, 2026

Opens in a new windowSecluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided
Fall Getaway Cabin Bordering Mark Twain National Forest w/Fire Pit & Trails

Fall Getaway Cabin Bordering Mark Twain National Forest w/Fire Pit & Trails

Mill Spring MO
$165 nightly
The price is $174 total per night from Oct 12 to Oct 13
$174 total
Oct 12 - Oct 13
Total with taxes and fees
This cabin features laundry facilities.
"Love how it was decorated"

Reviewed on Oct 4, 2026

Opens in a new windowFall Getaway Cabin Bordering Mark Twain National Forest w/Fire Pit & Trails
Cozy hobby farm cabin under the stars!

Cozy hobby farm cabin under the stars!

Patterson MO
Fully refundable
$115 nightly
The price is $121 total per night from Nov 2 to Nov 3
$121 total
Nov 2 - Nov 3
Total with taxes and fees
A hot tub is featured at this cabin, along with a garden and laundry facilities. Barbecue grills are provided for your convenience.
"Bed options are limited and not hotel quality. Tiny but efficient. Needed a room for a business trip. Only slept there, so limited insights as a vacation rental."

Reviewed on Oct 5, 2026

Opens in a new windowCozy hobby farm cabin under the stars!
Private lake, beach & hot tub, romantic getaway or family vaca

Private lake, beach & hot tub, romantic getaway or family vaca

Wappapello MO
A hot tub is featured at this vacation home, along with laundry facilities and barbecue grills.
"Great location to access the lake close by. Very picturesque location.Pics are a lil deceiving in that things are actually on a smaller scale IRL but still good amenities.Be aware, the pond is not swimmable but paddle boat is fun."

Reviewed on Aug 8, 2026

Get rates
Opens in a new windowPrivate lake, beach & hot tub, romantic getaway or family vaca
1/4 Mile To The Boat Launch & Beach 2 miles the Camp! Free WiFi, beautiful space

1/4 Mile To The Boat Launch & Beach 2 miles the Camp! Free WiFi, beautiful space

Wappapello MO
This cabin featured laundry facilities and barbecue grills.
"It was a terrible experience! I will NEVER rent off of this host again! Yes it was very hot outside, no one else we were visiting was burning up in their house. This place was so hot during the day we were literally sweating inside. It was ridiculous and I couldn't believe it. This place has NO privacy ..."

Reviewed on Jul 28, 2026

Get rates
Opens in a new window1/4 Mile To The Boat Launch & Beach 2 miles the Camp! Free WiFi, beautiful space
Sam A Baker State Park

Sam A Baker State Park

2 out of 5
5732 State Hwy Missouri 143 Patterson MO
$150 nightly
The price is $159 total per night from Oct 13 to Oct 14
$159 total
Oct 13 - Oct 14
Total with taxes and fees
This cabin includes a picnic area and barbecue grills. Take advantage of the free self parking.
"Janie and her staff were great and very flexible. We had all the hep we needed for everything. Will comeback asap!"

Reviewed on Dec 29, 2025

Opens in a new windowSam A Baker State Park
Clearwater Lake, cabin minutes from Bluff View Marina & boat dock

Clearwater Lake, cabin minutes from Bluff View Marina & boat dock

Piedmont MO
$140 nightly
The price is $147 total per night from Oct 11 to Oct 12
$147 total
Oct 11 - Oct 12
Total with taxes and fees
A garden is available at this cabin.
Opens in a new windowClearwater Lake, cabin minutes from Bluff View Marina & boat dock
Unique Treehouse & Mini Barn Combo!

Unique Treehouse & Mini Barn Combo!

Patterson MO
Fully refundable
$144 nightly
The price is $151 total per night from Oct 12 to Oct 13
$151 total
Oct 12 - Oct 13
Total with taxes and fees
A hot tub is featured at this bed & breakfast, along with a garden and laundry facilities.
Opens in a new windowUnique Treehouse & Mini Barn Combo!
Don't see what you're looking for?
See all available properties in Greenville
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Greenville?
Family trips are where the best memories are made, but traveling with youngsters can be difficult. These kid-friendly Greenville hotels offer perks that aim to keep visitors of all ages relaxed and happy: A cozy cabin with hot tub will help make your trip the most memorable one yet. It offers plenty of conveniences aimed at families, such as a playground and a nearby beach. Cozy Lakefront with Fireplace at Marina is another top pick. After a fun day of exploring, return to your comfortable room and amenities like a firepit and a balcony.
Where can I find cheap hotels in Greenville?
At Travelocity you'll find really nice hotels in Greenville at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Greenville rather than in Greenville. We may find you even better rates, too.
How do I find the best Greenville hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Greenville then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Greenville?
The cheapest hotel in Greenville is $121. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Greenville?
There are 44 hotels in Greenville on Travelocity.
What are the best hotels in Greenville?
Greenville has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Greenville for you!
When is the best time to visit Greenville?
If you want the joy of a fun-filled trip in peak season, visit Greenville during March, May and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in Greenville?
Based on historic data is usually the cheapest month to visit Greenville. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Greenville?
There are multiple hotels in Greenville that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Greenville. We have plenty of kid-friendly hotels in Greenville to choose from on Travelocity!
Why book a hotel in Greenville through Travelocity?
Because we have the top hotels in Greenville! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Greenville on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Greenville hotel reviews by fellow wanderers

Fall Getaway Cabin Bordering Mark Twain National Forest w/Fire Pit & Trails

Fall Getaway Cabin Bordering Mark Twain National Forest w/Fire Pit & Trails

4 out of 5
Posted 6 days ago
Travelocity Verified Review
"Love how it was decorated"
A verified traveler stayed at Fall Getaway Cabin Bordering Mark Twain National Forest w/Fire Pit & Trails
Fall Getaway Cabin Bordering Mark Twain National Forest w/Fire Pit & Trails

Explore More Ways to Travel with Travelocity