De Soto Vacation Packages 2026 from $508

De Soto flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

The Knight Center at Washington University

$508

per person

May 1 - May 4

found 1 day ago

Roundtrip flight included

New York (NYC) to St. Louis (STL)

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Self parking and a coffee shop are also offered on site.

The Wildwood Hotel

$607

per person

May 13 - May 16

found 10 hours ago

Roundtrip flight included

New York (JFK) to St. Louis (STL)

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like continental breakfast and free self parking.

Landing Apartments - Eureka

$759

per person

May 1 - May 4

found 1 day ago

Roundtrip flight included

New York (NYC) to St. Louis (STL)

This aparthotel features a 24-hour gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. Barbecue grills and a virtual front desk are also provided.

The Cheshire

$923

per person

May 13 - May 16

found 10 hours ago

Roundtrip flight included

New York (JFK) to St. Louis (STL)

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and free English breakfast each morning.

Hotel Indigo St Louis - Central West End by IHG

Central West End

$804

per person

May 13 - May 16

found 10 hours ago

Roundtrip flight included

New York (JFK) to St. Louis (STL)

This Art Deco hotel features 4 restaurants, a bar/lounge, and a 24-hour gym. Business travelers can take advantage of the free WiFi in public areas. Self parking, a coffee shop, and express check-in are also offered.

Top De Soto hotels deals

82 Acre Hobby Farm with Lincoln Log Cabin

De Soto MO

$257 nightly

$266 total

Feb 20 - Feb 21

Total with taxes and fees

This cabin features a garden, laundry facilities, and barbecue grills.

Kitchen

Washer

Secluded cabin on private property

De Soto MO

Get rates

This cabin features a garden, laundry facilities, and barbecue grills.

Kitchen

Washer

Pear Tree Inn St. Louis Arnold

1201 Drury Ln Arnold MO

Free Cancellation

Reserve now, pay when you stay

$90 nightly

$104 total

Feb 22 - Feb 23

Total with taxes and fees

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Pool

Breakfast included

Baymont Inn and Suites by Wyndham Farmington, MO

1625 W Columbia St Farmington MO

Free Cancellation

Reserve now, pay when you stay

$54 nightly

$62 total

Feb 22 - Feb 23

Total with taxes and fees

This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Pool

Breakfast included

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

7555 State Hwy Y French Village MO

$99 nightly

$106 total

Feb 23 - Feb 24

Total with taxes and fees

This cabin includes express check-out and a virtual front desk. Take advantage of the free self parking.

Baymont by Wyndham Festus

1200 W. Gannon Drive Festus MO

Free Cancellation

Reserve now, pay when you stay

$81 nightly

$93 total

Feb 17 - Feb 18

Total with taxes and fees

This hotel features an indoor pool and a gym. Families will appreciate the arcade/game room and barbecue grills. Relax with a drink at the bar/lounge and enjoy free perks like continental breakfast and free self parking.

Pool

Breakfast included

Don't see what you're looking for?

See all available properties in De Soto

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Sunrise Lake Beach

Why not spend a lazy afternoon at Sunrise Lake Beach during your trip to De Soto?

Clear Lake

Commune with nature and explore the great outdoors at Clear Lake during your travels in De Soto.

Sunrise Lake

Commune with nature and explore the great outdoors at Sunrise Lake during your travels in De Soto.

Frequently asked questions

How much are vacation packages to De Soto?

Your travel daydreams can become a reality in De Soto from just $508. Our package deals include flights and hotels, so organizing your itinerary will be a piece of cake. The only thing you'll have to concentrate on is getting out there and having a great time.

How long should my De Soto vacation be?

Many people choose to spend about 2 nights in De Soto, but how long you stay is your call. If you want to check out all the fantastic things this place offers, why not hang around a while longer?

Where can I get the best vacation package deals for De Soto?

Find your dream escape at Travelocity. With access to 400 airline partners and a whopping 1,000,000 hotels around the world, selecting the perfect De Soto package deal couldn't be easier.

Why should I book my De Soto vacation package via Travelocity?

From enticing destinations to fun experiences, we have everything you need to satisfy your wanderlust. Our 24/7 support will also make sure you're being taken care of before, during and after your vacation. And don't stress if you spot a lower price on your booking, we'll match it. That's our Price Match Guarantee.

Can I save money on my De Soto car rental if I bundle it with a hotel or flight?

Combining your flight, hotel and car into a De Soto vacation package is a surefire way to land the best prices. Plus, having your own car rental gives you absolute freedom to find your way to all the landmarks you're hoping to check out. Sitting 40 mi away from De Soto, Busch Stadium is one place that should have a place on your itinerary. Fasten your seat belt and make a day trip of it.

Which airport is best for De Soto?

Flying into De Soto will see you landing at Lambert-St. Louis Intl. Airport (STL). It's roughly 45 mi north of the downtown area.

What is there to do in De Soto?

Victoria Glaces Conservation Area Trailhead deserves a spot on your travel itinerary. After you've checked off this well-known attraction, simply roam the streets of De Soto and learn what really makes this cool destination tick.

Where should I stay when visiting De Soto?

Many travelers choose to check in to the Holiday Inn Club Vacations Timber Creek Resort At De Soto. It's a great base for your De Soto getaway.