Book Hotels in Clarksdale, MO
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Top Clarksdale hotels

Fairfield Inn & Suites by Marriott St. Joseph
4779 Tuscany Drive, St. Joseph, MO
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $133 total per night from Oct 26 to Oct 27
$133 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the free ...
"The Fairfield Inn & Suites by Marriott was a great choice! The price was very reasonable, and the rooms were clean, spacious, and comfortable. Everything felt fresh and well maintained, making for a relaxing stay. Excellent value—I would definitely stay here again."
Reviewed on Sep 22, 2025

Drury Inn & Suites St Joseph
4213 Frederick Ave, St. Joseph, MO
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $116 total per night from Oct 12 to Oct 13
$116 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"We would definitely stay here again! Beds were so comfortable and breakfast was wonderful!"
Reviewed on Sep 27, 2025

Stoney Creek Hotel St. Joseph
1201 N Woobine Rd, St. Joseph, MO
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $130 total per night from Oct 26 to Oct 27
$130 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
"Always like staying here. So friendly."
Reviewed on Sep 26, 2025

My Place Hotel St Joseph MO
3621 N Village Dr, St. Joseph, MO
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $88 total per night from Oct 13 to Oct 14
$88 total
Oct 13 - Oct 14
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the 24-hour business center. ...
"Really well priced with immaculate rooms. We needed pet friendly for our dog and didn't mind paying a bit more because the area was very safe."
Reviewed on Sep 27, 2025

Holiday Inn Express Hotel & Suites St. Joseph by IHG
3600 N. Village Dr., St. Joseph, MO
Fully refundable
$121 nightly
The price is $140 total per night from Oct 17 to Oct 18
$140 total
Oct 17 - Oct 18
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Clean facility and great location"
Reviewed on Sep 23, 2025

Red Roof Inn Cameron
501 Northland Drive, Cameron, MO
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $94 total per night from Oct 9 to Oct 10
$94 total
Oct 9 - Oct 10
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like continental breakfast and WiFi ...
Great Overnight Stay
"Parking was close, bed was comfy, room was nice and cool"
Reviewed on Sep 27, 2025

SureStay Hotel by Best Western Cameron
2210 US Highway 36, Cameron, MO
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $86 total per night from Oct 8 to Oct 9
$86 total
Oct 8 - Oct 9
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Staff at the 24-hour front desk can provide ...
"Lol. Hard to find but a great motel."
Reviewed on Sep 19, 2025

Hampton Inn St. Joseph
3928 Frederick Ave, St. Joseph, MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $107 total per night from Oct 26 to Oct 27
$107 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
"It was fine overall but not convenient to restaurants."
Reviewed on Sep 10, 2025

AmeriStay Inn
4502 SE US HWY 169, St. Joseph, MO
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $116 total per night from Oct 5 to Oct 6
$116 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. Express check-out, ...
"My wife and I had a great experience at Ameristay Inn. Check in was fast. The room was clean and comfortable. The breakfast was perfect..cereal, fruit, muffins, juice, milk, and coffee. Pet Friendly. A/C works great. Right by the highway. Gas stations and places to eat close by. We will stay ..."
Reviewed on Jul 31, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Clarksdale hotel reviews by fellow wanderers

My Place Hotel St Joseph MO
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"Really well priced with immaculate rooms. We needed pet friendly for our dog and didn't mind paying a bit more because the area was very safe. "
A verified traveler stayed at My Place Hotel St Joseph MO
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