Explore top 2026 5 Star Hotels in Southeastern United States

Name: The Charleston Place
Price range: $578 total
Rating: 9.6

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Top Southeastern United States 5 Star hotels

Waldorf Astoria Orlando - An Official Walt Disney World® Hotel

14200 Bonnet Creek Resort Lane Orlando FL

Fully refundableReserve now, pay when you stay

$368 nightly

$414 total

Oct 4 - Oct 5

Total with taxes and fees

This luxury resort features a golf course, a full-service spa, and 6 restaurants. There's fun for all ages with a lazy river and a children's club, and families ...

EAST Miami

788 Brickell Plaza Miami FL

Fully refundableReserve now, pay when you stay

$403 nightly

$455 total

Sep 27 - Sep 28

Total with taxes and fees

This smoke-free hotel features 3 restaurants, 4 outdoor pools, and a 24-hour gym. Relax with a drink at one of the 2 bars/lounges and get perks like free WiFi. ...

Kimpton EPIC Hotel by IHG

270 Biscayne Blvd Way Miami FL

Fully refundable

$243 nightly

$275 total

Sep 29 - Sep 30

Total with taxes and fees

This luxury hotel features a full-service spa, a marina, and 2 restaurants. Traveling on business? Take advantage of the 24-hour business center, free WiFi in ...

1 Hotel South Beach

2341 Collins Avenue Miami Beach FL

Fully refundableReserve now, pay when you stay

$545 nightly

$621 total

Oct 4 - Oct 5

Total with taxes and fees

A full-service spa, 3 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Relax with beach cabanas, sun loungers, and beach umbrellas. ...

Pier Sixty-Six (Pier 66)

2301 SE 17th St Fort Lauderdale FL

Fully refundableReserve now, pay when you stay

$309 nightly

$349 total

Oct 3 - Oct 4

Total with taxes and fees

This smoke-free hotel features a full-service spa, a marina, and 9 restaurants. Bring the family and enjoy the children's club, waterslide, and playground. Enjoy ...

Nobu Hotel Miami Beach

4525 Collins Ave Miami Beach FL

Fully refundableReserve now, pay when you stay

$296 nightly

$337 total

Sep 22 - Sep 23

Total with taxes and fees

A full-service spa, 2 restaurants, and 4 outdoor pools are all featured at this smoke-free resort. Relax with a drink at one of the 2 bars/lounges and get perks ...

InterContinental Miami by IHG

100 Chopin Plz Miami FL

Fully refundable

$239 nightly

$270 total

Sep 16 - Sep 17

Total with taxes and fees

A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9.4/10 Exceptional! (2,549 reviews)

"Perfection!"

Reviewed on Sep 14, 2026

InterContinental Buckhead Atlanta by IHG

3315 Peachtree Rd Ne Atlanta GA

Fully refundable

$238 nightly

$283 total

Sep 20 - Sep 21

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...

9/10 Wonderful! (1,001 reviews)

"Lovely hotel, very responsive to any requests"

Reviewed on Sep 15, 2026

Biltmore Hotel - Miami - Coral Gables

1200 Anastasia Ave Coral Gables FL

$322 nightly

$361 total

Sep 20 - Sep 21

Total with taxes and fees

This luxury hotel features a golf course, a full-service spa, and 4 restaurants. Traveling on business? Take advantage of the business center, laundry service, ...

9.2/10 Wonderful! (1,011 reviews)

"Our stay at the Biltmore did not disappoint! Everything exceeded expectations.Highly recommend this historic venue delivering their high level service for over 100 years!"

Reviewed on Sep 15, 2026

The Charleston Place

205 Meeting Street Charleston SC

Fully refundableReserve now, pay when you stay

$507 nightly

$578 total

Sep 20 - Sep 21

Total with taxes and fees

This hotel features an indoor pool, a gym, and a restaurant. Families will appreciate the onsite laundry facilities, kid-friendly dining, and in-room childcare. ...

9.6/10 Exceptional! (1,006 reviews)

"I had a wonderful stay at The Charleston Place. The hotel is beautiful, elegant, and very clean, with fresh flowers and beautiful greenery throughout the property that create a warm and welcoming atmosphere. The location is excellent, right in the heart of historic Charleston, making it very convenient ..."

Reviewed on Sep 14, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southeastern United States Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Southeastern United States to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Southeastern United States 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Southeastern United States before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.