Explore top 2026 5 Star Hotels in Otay Mesa West
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Top Otay Mesa West 5 Star hotels

Pendry San Diego
550 J Street San Diego CA
Fully refundableReserve now, pay when you stay
$340 nightly
The price is $395 total per night from Jan 7 to Jan 8
$395 total
Jan 7 - Jan 8
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,003 reviews)
The room was clean, tasteful, and quiet. The staff was very friendly and helpful. We had a wonderful time in Pendry.
Reviewed on Jan 1, 2026

The US Grant, a Luxury Collection Hotel, San Diego
326 Broadway San Diego CA
Fully refundableReserve now, pay when you stay
$294 nightly
The price is $341 total per night from Feb 6 to Feb 7
$341 total
Feb 6 - Feb 7
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...
9/10 Wonderful! (1,000 reviews)
Classic beautiful hotel
Reviewed on Dec 19, 2025

Shore House at The Del, LXR Hotels & Resorts
1500 Orange Avenue Coronado CA
$619 nightly
The price is $687 total per night from Jan 14 to Jan 15
$687 total
Jan 14 - Jan 15
Total with taxes and fees
A private beach, 7 restaurants, and 2 outdoor pools are all featured at this luxury resort. Relax with beach cabanas and sun loungers, and cool off with a drink ...
9.2/10 Wonderful! (118 reviews)
Luxurious
Reviewed on Dec 29, 2025

Beach Village at The Del, LXR Hotels & Resorts
1500 Orange Avenue Coronado CA
$783 nightly
The price is $863 total per night from Jan 19 to Jan 20
$863 total
Jan 19 - Jan 20
Total with taxes and fees
A private beach, 7 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy beachfront dining and relax with beach cabanas and sun ...
9/10 Wonderful! (122 reviews)
Great experience! Wonderful staff
Reviewed on Dec 9, 2025

The Bower Coronado
1417 Orange Ave Coronado CA
Fully refundableReserve now, pay when you stay
$279 nightly
The price is $302 total per night from Jan 8 to Jan 9
$302 total
Jan 8 - Jan 9
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
9.2/10 Wonderful! (161 reviews)
Overall it was a nice stay but not worth the high price tag. Room was clean but very small. Staff is friendly but hotel seems understaffed—lobby is empty a lot of the time and they barely answer the phone if you need something. Great view from the rooftop bar/restaurant and good food. Noisy if you ...
Reviewed on Dec 30, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Otay Mesa West hotel reviews by fellow wanderers

The DEXTRO Little Italy, BW Premier Collection
5 out of 5
Posted 19 hours ago
Travelocity Verified Review
"Staff was friendly and we were able to check in early without a problem. Room is clean and shower is great!"
A verified traveler stayed at The DEXTRO Little Italy, BW Premier Collection
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