Explore top 2026 5 Star Hotels in Otay Mesa West
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Top Otay Mesa West 5 Star hotels

Pendry San Diego
550 J Street San Diego CA
Fully refundableReserve now, pay when you stay
$360 nightly
The price is $418 total per night from Mar 19 to Mar 20
$418 total
Mar 19 - Mar 20
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,002 reviews)
We got there at noon and we did not get a room until 4PM - despite the staff assuring us they would have a room shortly when we arrived. The second day we had to ask for housekeeping to do our room several times and the room was not cleaned until 5PM. While most of the staff was polite one of the ...
Reviewed on Feb 17, 2026

The US Grant, a Luxury Collection Hotel, San Diego
326 Broadway San Diego CA
Fully refundableReserve now, pay when you stay
$341 nightly
The price is $396 total per night from Mar 8 to Mar 9
$396 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...
9/10 Wonderful! (1,004 reviews)
Wonderful property with friendly and excellent staff. We'll be back for sure!
Reviewed on Feb 22, 2026

Shore House at The Del, LXR Hotels & Resorts
1500 Orange Avenue Coronado CA
$619 nightly
The price is $687 total per night from Mar 1 to Mar 2
$687 total
Mar 1 - Mar 2
Total with taxes and fees
A private beach, 7 restaurants, and 2 outdoor pools are all featured at this luxury resort. Relax with beach cabanas and sun loungers, and cool off with a drink ...
9.2/10 Wonderful! (128 reviews)
Beautiful room. Family friendly pool and hot tub. The grounds are beautiful and easy access to the beach. Would HIGHLY recommend!
Reviewed on Feb 21, 2026

Beach Village at The Del, LXR Hotels & Resorts
1500 Orange Avenue Coronado CA
$925 nightly
The price is $1,017 total per night from Mar 23 to Mar 24
$1,017 total
Mar 23 - Mar 24
Total with taxes and fees
A private beach, 7 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy beachfront dining and relax with beach cabanas and sun ...
9.2/10 Wonderful! (127 reviews)
The room was spotless. The view was spectacular.
Reviewed on Feb 8, 2026

The Bower Coronado
1417 Orange Ave Coronado CA
Fully refundableReserve now, pay when you stay
$349 nightly
The price is $379 total per night from Feb 26 to Feb 27
$379 total
Feb 26 - Feb 27
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
9.2/10 Wonderful! (181 reviews)
Very clean. Great style
Reviewed on Feb 19, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Otay Mesa West hotel reviews by fellow wanderers

Wyndham San Diego Bayside
5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"Lovely room, location, location, location, they have the best location. Staff was awesome."
A verified traveler from Anchorage stayed at Wyndham San Diego Bayside
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