Explore top 2026 5 Star Hotels in Otay Mesa West

Start date: Check-in selected.
To Date
End date: Check-out

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight
Jan 5 - Jan 6
Tomorrow
Jan 6 - Jan 7
This weekend
Jan 9 - Jan 11
Next weekend
Jan 16 - Jan 18

Top Otay Mesa West 5 Star hotels

Pendry San Diego

Pendry San Diego

5 out of 5
550 J Street San Diego CA
Fully refundableReserve now, pay when you stay
$340 nightly
The price is $395 total per night from Jan 7 to Jan 8
$395 total
Jan 7 - Jan 8
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,003 reviews)
The room was clean, tasteful, and quiet. The staff was very friendly and helpful. We had a wonderful time in Pendry.

Reviewed on Jan 1, 2026

Opens in a new windowPendry San Diego
The US Grant, a Luxury Collection Hotel, San Diego

The US Grant, a Luxury Collection Hotel, San Diego

5 out of 5
326 Broadway San Diego CA
Fully refundableReserve now, pay when you stay
$294 nightly
The price is $341 total per night from Feb 6 to Feb 7
$341 total
Feb 6 - Feb 7
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...
9/10 Wonderful! (1,000 reviews)
Classic beautiful hotel

Reviewed on Dec 19, 2025

Opens in a new windowThe US Grant, a Luxury Collection Hotel, San Diego
Shore House at The Del, LXR Hotels & Resorts

Shore House at The Del, LXR Hotels & Resorts

5 out of 5
1500 Orange Avenue Coronado CA
$619 nightly
The price is $687 total per night from Jan 14 to Jan 15
$687 total
Jan 14 - Jan 15
Total with taxes and fees
A private beach, 7 restaurants, and 2 outdoor pools are all featured at this luxury resort. Relax with beach cabanas and sun loungers, and cool off with a drink ...
9.2/10 Wonderful! (118 reviews)
Luxurious

Reviewed on Dec 29, 2025

Opens in a new windowShore House at The Del, LXR Hotels & Resorts
Beach Village at The Del, LXR Hotels & Resorts

Beach Village at The Del, LXR Hotels & Resorts

5 out of 5
1500 Orange Avenue Coronado CA
$783 nightly
The price is $863 total per night from Jan 19 to Jan 20
$863 total
Jan 19 - Jan 20
Total with taxes and fees
A private beach, 7 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy beachfront dining and relax with beach cabanas and sun ...
9/10 Wonderful! (122 reviews)
Great experience! Wonderful staff

Reviewed on Dec 9, 2025

Opens in a new windowBeach Village at The Del, LXR Hotels & Resorts
The Bower Coronado

The Bower Coronado

5 out of 5
1417 Orange Ave Coronado CA
Fully refundableReserve now, pay when you stay
$279 nightly
The price is $302 total per night from Jan 8 to Jan 9
$302 total
Jan 8 - Jan 9
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
9.2/10 Wonderful! (161 reviews)
Overall it was a nice stay but not worth the high price tag. Room was clean but very small. Staff is friendly but hotel seems understaffed—lobby is empty a lot of the time and they barely answer the phone if you need something. Great view from the rooftop bar/restaurant and good food. Noisy if you ...

Reviewed on Dec 30, 2025

Opens in a new windowThe Bower Coronado
Don't see what you're looking for?
See all available properties in Otay Mesa West
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Otay Mesa West hotel reviews by fellow wanderers

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

5 out of 5
Posted 19 hours ago
Travelocity Verified Review
"Staff was friendly and we were able to check in early without a problem. Room is clean and shower is great!"
A verified traveler stayed at The DEXTRO Little Italy, BW Premier Collection
The DEXTRO Little Italy, BW Premier Collection

Explore More Ways to Travel with Travelocity