Explore top 2026 4 Star Hotels in Des Peres
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Top Des Peres 4 Star hotels
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $179 total per night from Jul 31 to Aug 1
$179 total
Jul 31 - Aug 1
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
8.6/10 Excellent! (4,136 reviews)
"Clean room. Nice amenities. Easy walking distance to lots of activities"
Reviewed on Jul 24, 2026
Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $135 total per night from Aug 7 to Aug 8
$135 total
Aug 7 - Aug 8
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
8.4/10 Very Good! (1,126 reviews)
"My overnight stay was okay. The pool was over crowded with children (both pools). Someone pulled the fire alarm after 9pm. The hotel is nice and I will stay there again. I just have to make sure no one is having a family reunion at the time I want to stay. It was too many to children."
Reviewed on Jul 23, 2026
Moonrise Hotel
6177 Delmar Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $237 total per night from Aug 9 to Aug 10
$237 total
Aug 9 - Aug 10
Total with taxes and fees
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$198 nightly
The price is $234 total per night from Aug 3 to Aug 4
$234 total
Aug 3 - Aug 4
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
Live by Loews - St.Louis
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $189 total per night from Aug 3 to Aug 4
$189 total
Aug 3 - Aug 4
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9.4/10 Exceptional! (1,266 reviews)
"Rooms where clean, hotel is in a great location, didnt get a change to check out the food but it was a great stay"
Reviewed on Jul 23, 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $126 total per night from Aug 3 to Aug 4
$126 total
Aug 3 - Aug 4
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...
9/10 Wonderful! (1,085 reviews)
"The hotel was super cool definitely something different than your typical hotels. The bar on the top had amazing views and the colorful room was definitely something different, but loved as well."
Reviewed on Jul 23, 2026
The Westin St. Louis
811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $164 total per night from Aug 6 to Aug 7
$164 total
Aug 6 - Aug 7
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.6/10 Excellent! (1,012 reviews)
"My room was not very clean. I had food on my wall and curtains. There was no full size mirrors like most hotels. The hotel does not have many amenities and its confusing to navigate. I got lost so many times trying to get to my room. The only plus was the breakfast."
Reviewed on Jul 23, 2026
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from Aug 23 to Aug 24
$173 total
Aug 23 - Aug 24
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,988 reviews)
"I was very disappointed with our stay, the experience fell well below expectations. Our room was not properly maintained. The curtains were torn when we checked in, and the shower was dirty. Although housekeeping attempted to clean it after we reported the issue, it was still not acceptably clean. ..."
Reviewed on Jul 24, 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $125 total per night from Aug 13 to Aug 14
$125 total
Aug 13 - Aug 14
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.8/10 Excellent! (1,336 reviews)
"Cute little room, nice restaurant below"
Reviewed on Jul 22, 2026
Hilton St. Louis at the Ballpark
1 S Broadway St. Louis MO
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $184 total per night from Aug 13 to Aug 14
$184 total
Aug 13 - Aug 14
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an indoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
7.6/10 Good! (1,219 reviews)
"They did not allowed us to go upstairs on roof top. If thats the case it should be noted somewhere online not when you book the hotel specifically for thay and you not able to go because you have kids. Room not clean. Windows and mirror dirty. Will not come back."
Reviewed on Jul 23, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels Des Peres
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Des Peres 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Des Peres will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Des Peres, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Des Peres hotel reviews by fellow wanderers
Hyatt Regency St. Louis at The Arch
5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Clean room. Nice amenities. Easy walking distance to lots of activities"
A verified traveler stayed at Hyatt Regency St. Louis at The Arch
