Book a hotel near Science Center of Iowa, Downtown Des Moines

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Top hotels close to Science Center of Iowa

Residence Inn Des Moines Downtown

Residence Inn Des Moines Downtown

3 out of 5
100 SW Water Street Des Moines IA
Free Cancellation
Reserve now, pay when you stay
0.12 mi from Science Center of Iowa
$93 nightly
The price is $104 total per night
$104 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features an indoor pool and a gym. Enjoy the hot tub and free perks like buffet breakfast and WiFi in public areas. Self parking, a 24-hour business center, and a free grocery shopping service are also offered.
Pool
Hot Tub
Hampton Inn & Suites Des Moines Downtown

Hampton Inn & Suites Des Moines Downtown

2.5 out of 5
120 Sw Water St Des Moines IA
Free Cancellation
Reserve now, pay when you stay
0.15 mi from Science Center of Iowa
$87 nightly
The price is $98 total per night
$98 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features an indoor pool and a gym. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. Self parking, a 24-hour business center, and dry cleaning are also offered.
Pool
Breakfast included
Surety Hotel, Autograph Collection

Surety Hotel, Autograph Collection

4 out of 5
206 6th Ave. Des Moines IA
Free Cancellation
Reserve now, pay when you stay
0.29 mi from Science Center of Iowa
$161 nightly
The price is $180 total per night
$180 total
Dec 19 - Dec 20
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. WiFi in public areas is free. Self parking, a lobby fireplace, and dry cleaning are also offered.
Pet friendly
Free WiFi
Renaissance Des Moines Savery Hotel

Renaissance Des Moines Savery Hotel

3.5 out of 5
401 Locust St Des Moines IA
Free Cancellation
Reserve now, pay when you stay
0.34 mi from Science Center of Iowa
$139 nightly
The price is $156 total per night
$156 total
Dec 19 - Dec 20
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Valet parking, a snack bar/deli, and express check-in are also offered.
Free airport shuttle
Free WiFi
Hyatt Place Des Moines/Downtown

Hyatt Place Des Moines/Downtown

3 out of 5
418 6th Avenue Des Moines IA
Free Cancellation
Reserve now, pay when you stay
0.41 mi from Science Center of Iowa
$101 nightly
The price is $113 total per night
$113 total
Dec 8 - Dec 9
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the free buffet breakfast each morning.
Pool
Breakfast included
Embassy Suites Hotel Des Moines Downtown

Embassy Suites Hotel Des Moines Downtown

3.5 out of 5
101 E Locust St Des Moines IA
Free Cancellation
Reserve now, pay when you stay
0.43 mi from Science Center of Iowa
$127 nightly
The price is $142 total per night
$142 total
Dec 11 - Dec 12
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free full breakfast each morning. Self parking, a 24-hour business center, and a picnic area are also offered.
Pool
Breakfast included
Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
0.45 mi from Science Center of Iowa
$149 nightly
The price is $167 total per night
$167 total
Dec 4 - Dec 5
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy the sauna and free continental breakfast each morning.
Hot Tub
Breakfast included
Staybridge Suites Des Moines Downtown by IHG

Staybridge Suites Des Moines Downtown by IHG

3 out of 5
201 E. Locust Street Des Moines IA
Free Cancellation
0.49 mi from Science Center of Iowa
$95 nightly
The price is $107 total per night
$107 total
Dec 29 - Dec 30
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free buffet breakfast each morning.
Pool
Hot Tub
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Free Cancellation
Reserve now, pay when you stay
0.51 mi from Science Center of Iowa
$139 nightly
The price is $155 total per night
$155 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. WiFi in public areas is free. Valet parking, a business center, and a coffee shop are also offered.
Free WiFi
Restaurant
Holiday Inn Express & Suites Des Moines Downtown by IHG

Holiday Inn Express & Suites Des Moines Downtown by IHG

2.5 out of 5
333 SW 11th St Des Moines IA
Free Cancellation
0.51 mi from Science Center of Iowa
$99 nightly
The price is $111 total per night
$111 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and free perks like on-the-go breakfast and free self parking.
Pool
Hot Tub
Hilton Des Moines Downtown

Hilton Des Moines Downtown

3.5 out of 5
435 Park Street Des Moines IA
Free Cancellation
Reserve now, pay when you stay
0.56 mi from Science Center of Iowa
$136 nightly
The price is $152 total per night
$152 total
Dec 20 - Dec 21
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and free airport shuttle. A bar/lounge, a 24-hour front desk, and a coffee shop are also provided.
Pool
Free airport shuttle
Comfort Inn & Suites Event Center

Comfort Inn & Suites Event Center

2.5 out of 5
929 3rd St Des Moines IA
Free Cancellation
Reserve now, pay when you stay
0.77 mi from Science Center of Iowa
$84 nightly
The price is $94 total per night
$94 total
Dec 19 - Dec 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Science Center of Iowa hotels essential information

Accommodation
768 hotels
Lowest Price
$94
Highest Price
$180
Popular hotels
Hotel Fort Des Moines, Curio Collection by Hilton, Des Lux Hotel, Residence Inn Des Moines Downtown, Hampton Inn & Suites Des Moines Downtown, Hyatt Place Des Moines/Downtown, Embassy Suites Hotel Des Moines Downtown, Hilton Des Moines Downtown, Staybridge Suites Des Moines Downtown by IHG, Surety Hotel, Autograph Collection, Renaissance Des Moines Savery Hotel, Holiday Inn Express & Suites Des Moines Downtown by IHG, Comfort Inn & Suites Event Center

Recent Science Center of Iowa hotel reviews by fellow wanderers

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

5 out of 5
Posted 21 hours ago
Travelocity Verified Review
"Lovely hotel & staff"
A verified traveler stayed at Hotel Fort Des Moines, Curio Collection by Hilton
Hotel Fort Des Moines, Curio Collection by Hilton

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