Book Hotels in O Brien, FL
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Top O Brien hotels

Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy
1699 NE Co Rd 337, High Springs, FL
$150 nightly
The price is $165 total per night from Nov 2 to Nov 3
$165 total
Nov 2 - Nov 3
Total with taxes and fees
This cabin features a virtual front desk. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including ...
Such a happy experience and makes having a pet even more fun. Can wait to do it again!
Reviewed on Oct 23, 2025

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
16367 NW 167TH BLVD, Alachua, FL
Fully refundable
$117 nightly
The price is $132 total per night from Nov 23 to Nov 24
$132 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
We stopped here on our way to the Florida Keys and it was a nice stay. No complaints!
Reviewed on Oct 20, 2025

Comfort Suites Lake City
3690 W Us Highway 90, Lake City, FL
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $104 total per night from Nov 2 to Nov 3
$104 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Overall Great
Reviewed on Oct 20, 2025

Hampton Inn & Suites Lake City
450 SW Florida Gateway Drive, Lake City, FL
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $118 total per night from Nov 2 to Nov 3
$118 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Convenient
Reviewed on Oct 22, 2025

Best Western Plus Lake City
350 SW Florida Gateway Dr, Lake City, FL
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $91 total per night from Nov 2 to Nov 3
$91 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Friendly staff , comfortable beds and decent. Breakfast .
Reviewed on Oct 24, 2025

Tru by Hilton Lake City
284 NW Centurion Court, Lake City, FL
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $123 total per night from Nov 2 to Nov 3
$123 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
I actually met a friend at the Cracker Barrel, I'm sure the food was fine at the hotel.
Reviewed on Oct 21, 2025

La Quinta Inn & Suite by Wyndham Lake City
165NW CALI DRIVE, Lake City, FL
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $108 total per night from Nov 2 to Nov 3
$108 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Trip to Florida
Very nice hotel, close to interstate, quiet, multiple stories.
Reviewed on Oct 22, 2025

Holiday Inn & Suites Lake City by IHG
213 Sw Commerce Dr, Lake City, FL
Fully refundable
$93 nightly
The price is $105 total per night from Nov 2 to Nov 3
$105 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Breakfast was not included with stay, $12.99 for breakfast even if you stay at hotel.
Reviewed on Oct 13, 2025

Holiday Inn Express & Suites Live Oak by IHG
6694 Us Highway 129, Live Oak, FL
Fully refundable
$125 nightly
The price is $138 total per night from Nov 9 to Nov 10
$138 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests ...
Clean and kind
Reviewed on Oct 18, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent O Brien hotel reviews by fellow wanderers

Best Western Plus Lake City
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Friendly staff , comfortable beds and decent. Breakfast ."
A verified traveler stayed at Best Western Plus Lake City
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