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Top O Brien hotels

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

obrien FL
A gym is featured at this vacation home, along with a garden and laundry facilities. There's fun for all ages with a playground and an arcade/game room, and ...
We had a BEAUTIFUL and relaxing stay at this river rental. Everything was so neat and organized with extras like kayaks, a canoes, games and what not. And it is just 0.5 miles from Royal Springs. The owners were quick to respond to any questions we had and we even got to meet them while they were ...

Reviewed on Mar 30, 2026

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Opens in a new windowRoyal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

2 out of 5
1699 NE Co Rd 337 High Springs FL
$229 nightly
The price is $252 total per night from May 18 to May 19
$252 total
May 18 - May 19
Total with taxes and fees
This cabin features a virtual front desk. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including ...
Just perfect

Reviewed on May 13, 2026

Opens in a new windowPostcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 out of 5
16367 NW 167TH BLVD Alachua FL
Fully refundable
$88 nightly
The price is $99 total per night from Jun 14 to Jun 15
$99 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Clean room, new rooms

Reviewed on May 15, 2026

Opens in a new windowHoliday Inn Express & Suites Alachua - Gainesville Area by IHG
Comfort Suites Lake City

Comfort Suites Lake City

2.5 out of 5
3690 W Us Highway 90 Lake City FL
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $130 total per night from May 25 to May 26
$130 total
May 25 - May 26
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
No beach access. Front of hotel under construction- you have to go thru a small plywood area to get inside. No parking and the hotel smells like mold. Nothing like the pictures online. Avoid at all costs. Are son’s asthma is acting up because of how bad the hotel is. So upset that Expedia had this ...

Reviewed on May 9, 2026

Opens in a new windowComfort Suites Lake City
Best Western Plus Lake City

Best Western Plus Lake City

2.5 out of 5
350 SW Florida Gateway Dr Lake City FL
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $111 total per night from May 17 to May 18
$111 total
May 17 - May 18
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Great coffee machine and breakfast 😋 convenient.

Reviewed on May 14, 2026

Opens in a new windowBest Western Plus Lake City
La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 out of 5
165NW CALI DRIVE Lake City FL
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from May 31 to Jun 1
$112 total
May 31 - Jun 1
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Front desk staff were all amazing with excellent hospitality as well as kindness. Will definitely be staying here again for future trips.

Reviewed on May 14, 2026

Opens in a new windowLa Quinta Inn & Suite by Wyndham Lake City
Americas Best Value Inn Lake City

Americas Best Value Inn Lake City

2 out of 5
3835 West US Highway 90 Lake City FL
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $76 total per night from May 17 to May 18
$76 total
May 17 - May 18
Total with taxes and fees
An outdoor pool is featured at this motel, along with free self parking. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. ...
AC works. No usb ports, shower smaller than in my rv (and that is REALLY small). Breakfast was a muffin in a paper bag and a banana. If other people had been honest on their review we would never have stayed here. Hotel was really run down motel when you park in front of your door.

Reviewed on May 15, 2026

Opens in a new windowAmericas Best Value Inn Lake City
Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center

2 out of 5
3340 W US Highway 90 Lake City FL
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $71 total per night from May 19 to May 20
$71 total
May 19 - May 20
Total with taxes and fees
Staff at the 24-hour front desk can provide around-the-clock assistance. Take advantage of the free self parking.
The staff is always very accommodating, I accidentally unplugged the cable to the tv so I couldn't watch TV, i went up to the desk and she called for help and he beat me to my room and fixed it immediately, of course I had no idea I unplugged it. They are always helpful and best of all leave me alone, ...

Reviewed on May 13, 2026

Opens in a new windowMotel 6 – Lake City, Fl – Medical Center
Little River Spring Cave divers poolside Hideaway

Little River Spring Cave divers poolside Hideaway

O'Brien FL
An outdoor pool is featured at this apartment, along with a garden.
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Opens in a new windowLittle River Spring Cave divers poolside Hideaway
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in O Brien?
Family vacations are where treasured memories are made, but traveling with youngsters can be tricky. These kid-friendly O Brien hotels offer perks designed to keep adventurers of all ages relaxed and happy: The whole team will enjoy staying at Cozy OBrien Home w/Fire Pit & Patio Near 3 Rivers. A firepit and free WiFi are just a few of the things that help make this hotel an attractive option. 1 ½ Acre OBrien Home with Fire Pit - Near River! is another top place to stay. After a big day of exploring, return to your comfy room and amenities like a deck and a firepit.
Where can I find cheap hotels in O Brien?
At Travelocity you'll find really nice hotels in O Brien at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near O Brien rather than in O Brien. We may find you even better rates, too.
How do I find the best O Brien hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in O Brien then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in O Brien?
The cheapest hotel in O Brien is $71. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in O Brien?
There are 377 hotels in O Brien on Travelocity.
What are the best hotels in O Brien?
O Brien has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in O Brien for you!
When is the best time to visit O Brien?
If you want the joy of a fun-filled trip in peak season, visit O Brien during March, November and December. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, April and June.
When is the cheapest time to stay in O Brien?
Based on historic data is usually the cheapest month to visit O Brien. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in O Brien?
There are multiple hotels in O Brien that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to O Brien. We have plenty of kid-friendly hotels in O Brien to choose from on Travelocity!
Why book a hotel in O Brien through Travelocity?
Because we have the top hotels in O Brien! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in O Brien on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent O Brien hotel reviews by fellow wanderers

Courtyard By Marriott Lake City

Courtyard By Marriott Lake City

5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"This hostel was so nice and clean! It’s close to the highway and a lot of restaurants!! If you need somewhere to stay I highly recommend! "
A verified traveler stayed at Courtyard By Marriott Lake City
Courtyard By Marriott Lake City

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