Book a hotel near Santa Fe River, Florida

Name: Quality Inn I-75 at Exit 399
Price range: $81

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Hotels near Santa Fe River

Rum Island Springs Cabin

Fort White, FL

1.57 mi from Santa Fe River

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This campground includes a garden and barbecue grills.

Kitchen

Air conditioning

Renovated 3 BR Near Ginnie Springs

High Springs, FL

3.13 mi from Santa Fe River

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This vacation home includes a garden and barbecue grills.

Kitchen

Air conditioning

Charming Santa Fe River Cottage - 10-15 min from 3 of FLA's most popular springs

Fort White, FL

3.66 mi from Santa Fe River

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This cottage features barbecue grills.

Free WiFi

Kitchen

Private 12 acre Ranch sleeps up to 10 on The Santa Fe River.

Branford, FL

3.85 mi from Santa Fe River

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This vacation home includes a garden and barbecue grills.

Free WiFi

Kitchen

Enjoy the Countryside! Near Springs & State Parks!

High Springs, FL

4.65 mi from Santa Fe River

This property includes a garden and barbecue grills.

Free WiFi

Pet friendly

Santa Fe Landing Close to Ginne Springs & Ichetucknee Springs

Branford, FL

5.61 mi from Santa Fe River

A gym is featured at this vacation home, along with a garden and barbecue grills.

Kitchen

Air conditioning

Santa Fe Landing 1 Big Bedroom Close to Ginnie and Ichetucknee

Branford, FL

5.61 mi from Santa Fe River

A gym is featured at this vacation home, along with a garden and barbecue grills.

Free WiFi

Kitchen

Hilltop House

Fort White, FL

5.88 mi from Santa Fe River

This vacation home includes a garden and barbecue grills.

Kitchen

Air conditioning

Charming Downtown High Springs Cottage

High Springs, FL

6.16 mi from Santa Fe River

A garden is available at this vacation home.

Kitchen

Air conditioning

Holiday Inn Express & Suites Alachua - Gainesville Area, an IHG Hotel

16367 NW 167TH BLVD, Alachua, FL, 32615

Free Cancellation

10.93 mi from Santa Fe River

This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the spa tub and free perks like buffet breakfast and free self parking.

Pool

Free WiFi

Americas Best Value Inn Alachua

16100 NW US Highway 441, Alachua, FL, 32615

Free Cancellation

Reserve now, pay when you stay

11.12 mi from Santa Fe River

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the express check-out. Enjoy the outdoor pool and conveniences like a 24-hour front desk and laundry facilities.

Pool

Free WiFi

Quality Inn I-75 at Exit 399

15960 NW US Highway 441, Alachua, FL, 32615

Free Cancellation

Reserve now, pay when you stay

11.49 mi from Santa Fe River

An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. Staff at the 24-hour front desk can provide around-the-clock assistance.

Pool

Free WiFi

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels Close to Santa Fe River

Your next vacation is around the corner. The kids are out of school, you and the spouse have two weeks off, and it’s about time to get the heck out of dodge. You must experience the culture and see the sights. Book your stay Santa Fe River hotels with us at Travelocity and enjoy the trip of a lifetime.

Finally, you can stay near the sites you’ve only read about in books. Now they are next door. Start fresh in the morning with the amazing views from your balcony. Then hop on any number of tour buses and take postcard-worthy pictures of the attractions you once thought couldn’t be real, but now you find them through your lens. Hotels near Santa Fe River will offer you the best in prices, activities, amenities, dining, and nightlife.

You may not want to imitate the Griswald’s--that’s been done one too many times—but you do want to have a memorable trip. With Travelocity’s long list of cheap hotels near Santa Fe River, you’re sure to find the perfect place to stay within your preferred budget. We’ll match a lower price and refund the difference. Book now and let us make your next vacation the easiest of your life.