Book a hotel near Santa Fe River, Florida

Name: Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Price range: $109 total

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Top hotels close to Santa Fe River

Ginnie Springs Hidden Scuba Oasis Retreat! Only 1 minute from Ginnie Springs

High Springs FL

0.8 mi from Santa Fe River

Get rates

A hot tub is featured at this vacation home, along with a garden and laundry facilities. There's fun for all ages with a playground and an arcade/game room, and barbecue grills are available on site.

Hot Tub

Kitchen

The Rustic River Retreat at Ginnie Springs

High Springs FL

1.24 mi from Santa Fe River

Get rates

This vacation home featured laundry facilities and barbecue grills.

Kitchen

Washer

Rum Island Springs Cabin

Fort White FL

1.57 mi from Santa Fe River

Get rates

This campground features a garden, laundry facilities, and barbecue grills.

Kitchen

Washer

Cozy 3-bedroom house in charming High Springs

High Springs FL

1.65 mi from Santa Fe River

Get rates

This vacation home features a garden, laundry facilities, and barbecue grills.

Kitchen

Washer

Cozy 1 bedroom with loft cabin in High Springs 7 minutes from Ginnie Springs

High Springs FL

2.49 mi from Santa Fe River

Get rates

This cabin features laundry facilities.

Kitchen

Washer

Santa Fe River Front, Luxury Retreat near Ginnie Springs and Ichetucknee

Fort White FL

3.51 mi from Santa Fe River

Get rates

This cabin featured laundry facilities and barbecue grills.

Kitchen

Washer

Charming Santa Fe River Cottage - 10-15 min from 3 of FLA's most popular springs

Fort White FL

3.66 mi from Santa Fe River

Get rates

This cottage featured laundry facilities and barbecue grills.

Kitchen

Washer

Private 12 acre Ranch sleeps up to 8 on The Santa Fe River.

high springs FL

3.85 mi from Santa Fe River

Get rates

This vacation home features a garden, laundry facilities, and barbecue grills.

Kitchen

Washer

Private, 1 Mile to Poe, 4 miles to Blue, 6 Miles to Ginnie. Tent/Camper camping

High Springs FL

4.12 mi from Santa Fe River

$57 nightly

$61 total

May 31 - Jun 1

Total with taxes and fees

This campground features barbecue grills.

Parking available

Barbecue grill

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

1699 NE Co Rd 337 High Springs FL

5.15 mi from Santa Fe River

$224 nightly

$246 total

Jun 24 - Jun 25

Total with taxes and fees

This cabin features a virtual front desk. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including food and water bowls. Take advantage of the free self parking.

Kitchen

Pet friendly

BlueGem Motel

19544 NW US Hwy 441 High Springs FL

Free Cancellation

Reserve now, pay when you stay

5.96 mi from Santa Fe River

$106 nightly

$119 total

Jun 9 - Jun 10

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A terrace and barbecue grills are also provided.

Parking included

Free WiFi

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

16367 NW 167TH BLVD Alachua FL

10.95 mi from Santa Fe River

$97 nightly

$109 total

Jun 21 - Jun 22

Total with taxes and fees

This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

Don't see what you're looking for?

See all available properties in Santa Fe River

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santa Fe River hotels essential information

Accommodation	445 hotels
Lowest Price	$61
Highest Price	$246
Popular hotels	Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy, Ginnie Springs Hidden Scuba Oasis Retreat! Only 1 minute from Ginnie Springs, The Rustic River Retreat at Ginnie Springs, Rum Island Springs Cabin, Cozy 3-bedroom house in charming High Springs, Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, Cozy 1 bedroom with loft cabin in High Springs 7 minutes from Ginnie Springs, Santa Fe River Front, Luxury Retreat near Ginnie Springs and Ichetucknee, Private, 1 Mile to Poe, 4 miles to Blue, 6 Miles to Ginnie. Tent/Camper camping, BlueGem Motel, Charming Santa Fe River Cottage - 10-15 min from 3 of FLA's most popular springs, Private 12 acre Ranch sleeps up to 8 on The Santa Fe River.

Recent Santa Fe River hotel reviews by fellow wanderers

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

4 out of 5

Posted 19 hours ago

Travelocity Verified Review

"Breakfast was great, bed was comfortable. Room was clean. However, the elevator on 4th floor didn’t work an it was a hassle to carry bags down stairs."

A verified traveler stayed at Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

5 out of 5

Posted 1 day ago

Travelocity Verified Review

"Everything is thought of for you! Firewood and starter, coffee, water and s’mores. Just bring your food and snacks. I couldn’t ask for much more!"

A verified traveler stayed at Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

BlueGem Motel

5 out of 5

Posted 1 day ago

Travelocity Verified Review

"Blue Gem motel was the perfect stay for us for our weekend event at Camp Kulaqua which was only a few minutes down the road. I was a lil hesitant since it was a “motel”. However the room was nicely decorated and spacious. The bed was a super comfy king bed. I travel a lot and was impressed with how comfortable I slept. The AC was nice and cold. The bathroom was on the smaller side but it did it’s job. I loved that the car was right in front of our room which made loading and unloading super easy. They also have Adirondack chairs which was a nice touch. A couple doors down there was an ice machine and a water bottle filler. The room had a mini fridge, small coffee maker and microwave. I was in need of a blower dryer and iron. The front office provided those without any issues. They actually gave me the option of iron or a nice steamer. Super nice front office staff. In the office they had a few complimentary snacks. And cold inexpensive drinks for $. If you’re looking for luxury or newer place to stay- this might not be it. But for us, it was perfect. We’ll be staying here in the future."

A verified traveler stayed at BlueGem Motel

Cozy 1 bedroom with loft cabin in High Springs 7 minutes from Ginnie Springs

4 out of 5

Posted 2 weeks ago

Travelocity Verified Review

"Good location. Very private and quiet. Only 10 min from Ginnie Springs. Had lots of natural lighting from the big windows on the walls. AC was good in the heat. Very cute area."

A verified traveler stayed at Cozy 1 bedroom with loft cabin in High Springs 7 minutes from Ginnie Springs

Santa Fe River Front, Luxury Retreat near Ginnie Springs and Ichetucknee

5 out of 5

Posted 3 weeks ago

Travelocity Verified Review

"I recently stayed at a fantastic Vrbo property over the weekend and couldn't be happier with my experience. The location was absolutely beautiful, surrounded by stunning views that made for a perfect getaway. The property was impeccably clean, with every detail taken care of, ensuring a comfortable stay. Additionally, the host was incredibly accommodating, always available to answer questions and make sure everything went smoothly. I highly recommend this spot for anyone looking to relax and enjoy a lovely retreat!"

A verified traveler stayed at Santa Fe River Front, Luxury Retreat near Ginnie Springs and Ichetucknee