Book a hotel near Santa Fe River, Florida

Name: DoubleTree by Hilton Gainesville
Price range: $91

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Hotels near Santa Fe River

BlueGem Motel

19544 NW US Hwy 441, High Springs, FL

Free Cancellation

Reserve now, pay when you stay

5.98 mi from Santa Fe River

$89

per night

Oct 22 - Oct 23

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A terrace and barbecue grills are also provided.

Parking included

Free WiFi

Big Cypress Lodge on Sante Fe River-Sleeps 14, Bring horses, RV and your boat!

6.97 mi from Santa Fe River

Get rates

This cabin includes a garden and barbecue grills.

Pet friendly

Kitchen

Holiday Inn Express & Suites Alachua - Gainesville Area, an IHG Hotel

16367 NW 167TH BLVD, Alachua, FL

Free Cancellation

10.93 mi from Santa Fe River

$108

per night

Oct 29 - Oct 30

This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the spa tub and free perks like buffet breakfast and free self parking.

Breakfast included

Hot Tub

O'LE LADYBUG COTTAGE

11.07 mi from Santa Fe River

$109

per night

Oct 16 - Oct 17

This vacation home includes a garden and barbecue grills.

Kitchen

Barbecue grill

Americas Best Value Inn Alachua

16100 NW US Highway 441, Alachua, FL

Free Cancellation

Reserve now, pay when you stay

11.12 mi from Santa Fe River

$82

per night

Oct 8 - Oct 9

An outdoor pool, free self parking, and laundry facilities are featured at this motel. WiFi in public areas is free. Express check-out is provided and the front desk is staffed around-the-clock.

Breakfast available

Pet friendly

Royal Inn

16305 NW 162nd Lane, Alachua, FL

Free Cancellation

Reserve now, pay when you stay

11.13 mi from Santa Fe River

$71

per night

Oct 8 - Oct 9

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Express check-out and laundry facilities are also provided.

Pet friendly

Parking included

Hampton Inn & Suites Alachua I-75

15930 Northwest 163rd Lane, Alachua, FL

Free Cancellation

Reserve now, pay when you stay

11.17 mi from Santa Fe River

$124

per night

Oct 12 - Oct 13

This hotel features an outdoor pool and a gym. Business travelers can take advantage of the business center. Free self parking and luggage storage are also offered on site.

Pet friendly

Pool

Quality Inn Alachua - Gainesville Area

15960 NW US Highway 441, Alachua, FL

Free Cancellation

Reserve now, pay when you stay

11.49 mi from Santa Fe River

$80

per night

Oct 8 - Oct 9

An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi in public areas. Staff at the 24-hour front desk can provide around-the-clock assistance.

Breakfast included

Pet friendly

Travelodge by Wyndham Alachua

15920 Nw Hwy 441, Alachua, FL

Free Cancellation

Reserve now, pay when you stay

11.6 mi from Santa Fe River

$59

per night

Oct 11 - Oct 12

An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. There's a picnic area and multilingual staff can provide around-the-clock assistance.

Breakfast included

Pet friendly

Best Western Gateway Grand

4200 NW 97th Blvd, Gainesville, FL

Free Cancellation

Reserve now, pay when you stay

17.86 mi from Santa Fe River

$101

per night

Oct 22 - Oct 23

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Enjoy the 24-hour gym and free perks like buffet breakfast and free self parking.

Breakfast included

Hot Tub

La Quinta by Wyndham Gainesville

908 NW 69 Terrace, Gainesville, FL

Free Cancellation

Reserve now, pay when you stay

20.77 mi from Santa Fe River

$104

per night

Oct 8 - Oct 9

This traditional motel includes 5 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free continental breakfast and free self parking.

Breakfast included

Pet friendly

DoubleTree by Hilton Gainesville

3726 Sw 40th Blvd, Gainesville, FL

Free Cancellation

Reserve now, pay when you stay

24.02 mi from Santa Fe River

$91

per night

Oct 11 - Oct 12

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the gym and perks like free self parking and free WiFi. A terrace, a garden, and a picnic area are also on offer.

Breakfast available

Pool

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels Close to Santa Fe River

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You may not want to imitate the Griswald’s--that’s been done one too many times—but you do want to have a memorable trip. With Travelocity’s long list of cheap hotels near Santa Fe River, you’re sure to find the perfect place to stay within your preferred budget. We’ll match a lower price and refund the difference. Book now and let us make your next vacation the easiest of your life.

Santa Fe River hotels essential information

Accommodation	1,167 hotels
Lowest Price	$59
Highest Price	$124
Popular hotels	BlueGem Motel, Best Western Gateway Grand, Big Cypress Lodge on Sante Fe River-Sleeps 14, Bring horses, RV and your boat!, Holiday Inn Express & Suites Alachua - Gainesville Area, an IHG Hotel, Travelodge by Wyndham Alachua, Quality Inn Alachua - Gainesville Area, Americas Best Value Inn Alachua, Royal Inn, Hampton Inn & Suites Alachua I-75, O'LE LADYBUG COTTAGE, La Quinta by Wyndham Gainesville, DoubleTree by Hilton Gainesville

Recent Santa Fe River hotel reviews by fellow wanderers

Holiday Inn Express & Suites Alachua - Gainesville Area, an IHG Hotel

5 out of 5

Posted 1 day ago

Travelocity Verified Review

"Property is in good condition, parking was limited by a lot of trucks taking up multiple parking spots, only parking left was on sides, not in a parking spot. Breakfast was very good, lots of choices."

A verified traveler from Boynton Beach stayed at Holiday Inn Express & Suites Alachua - Gainesville Area, an IHG Hotel