Book Hotels in Lithium, MO

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Lithium hotels

Silo Farm Haus- located in the heart of wine country!

Silo Farm Haus- located in the heart of wine country!

Ste. Genevieve MO
$331 nightly
The price is $370 total per night from Nov 1 to Nov 2
$370 total
Nov 1 - Nov 2
Total with taxes and fees
This vacation home features laundry facilities.
"The photos don't do this place justice, it's absolutely stunning inside and out. It was so peaceful, with such beautiful scenery. I got to enjoy my morning coffee on the porch swing and watch the sun rise over the hills. Inside was very clean, and I absolutely LOVED all of the decor! It was the perfect ..."

Reviewed on Oct 15, 2026

Opens in a new windowSilo Farm Haus- located in the heart of wine country!
Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

2.5 out of 5
2020 Jefferson St Perryville MO
Fully refundable
$95 nightly
The price is $109 total per night from Nov 29 to Nov 30
$109 total
Nov 29 - Nov 30
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Excellent stay , couldn't believe the property was 10 years old , it looks like it was just built , great place , highly recommend ."

Reviewed on Oct 28, 2026

Opens in a new windowHoliday Inn Express & Suites Perryville by IHG
Microtel Inn & Suites by Wyndham Sainte Genevieve

Microtel Inn & Suites by Wyndham Sainte Genevieve

2.5 out of 5
21958 Hwy 32 Ste Genevieve MO
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $102 total per night from Nov 15 to Nov 16
$102 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
"The hotel was clean, but they had the doors locked at 9 pm for trying to check in. The clerk was hard to understand. He wasn’t rude at all, but the whole thing felt awkward. We never saw another staff member. Te light in the room didn’t work and the adjoining door wouldn’t latch. For the price, the ..."

Reviewed on Oct 29, 2026

Opens in a new windowMicrotel Inn & Suites by Wyndham Sainte Genevieve
Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL

2.5 out of 5
2150 State Street Chester IL
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $88 total per night from Nov 8 to Nov 9
$88 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
"Nice, big building with big, comfy lobby. We were at the end of a long hallway so it was nice and private for us. Woman in charge was very pleasant and competent. Got us checked in right away."

Reviewed on Oct 30, 2026

Opens in a new windowBaymont by Wyndham Chester IL
Triangle Inn Motel

Triangle Inn Motel

2 out of 5
897 Ste Genevieve Dr Ste Genevieve MO
Free self parking is available and the hotel's multilingual staff can provide around-the-clock assistance. WiFi in public areas is free. A free grocery shopping ...
"The nicest budget motel we have ever stayed in!"

Reviewed on Oct 14, 2026

Get rates
Opens in a new windowTriangle Inn Motel
Quality Inn Perryville I-55

Quality Inn Perryville I-55

2.5 out of 5
1517 S. Perryville Blvd. Perryville MO
Fully refundable
$64 nightly
The price is $73 total per night from Nov 22 to Nov 23
$73 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features an outdoor pool and a gym. Enjoy the hot tub and free perks like daily breakfast and free self parking. The front desk is staffed around-the-clock ...
"Clean Room"

Reviewed on Oct 26, 2026

Opens in a new windowQuality Inn Perryville I-55
Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville

2 out of 5
1500 Liberty Street Perryville MO
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $82 total per night from Nov 1 to Nov 2
$82 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Opens in a new windowDays Inn by Wyndham Perryville
Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville

2 out of 5
1119 Vincent Dr Perryville MO
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $79 total per night from Nov 8 to Nov 9
$79 total
Nov 8 - Nov 9
Total with taxes and fees
This motel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Opens in a new windowSuper 8 by Wyndham Perryville
Perryville RV Resort

Perryville RV Resort

2 out of 5
300 Lake Dr Perryville MO
$81 nightly
The price is $93 total per night from Nov 1 to Nov 2
$93 total
Nov 1 - Nov 2
Total with taxes and fees
An outdoor pool is featured at this holiday park, along with free self parking. A garden is also provided.
Opens in a new windowPerryville RV Resort
Don't see what you're looking for?
See all available properties in Lithium
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Lithium?
From thoughtful amenities to more room to move, kid-friendly hotels come with features that can help turn a good family vacation into a fantastic one. These Lithium options make vacationing with young ones a piece of cake: Lost Arrowhead Lodge - Secluded - Pool - WiFi - 1 Hr South of St.Louis will help make your adventure the most memorable one yet. It features a host of nice touches, such as a swimming pool and animal viewing activities. Also look up June Bugs Loft. It offers a king bed, internet access and plenty of opportunities to spend time together.
Where can I find cheap hotels in Lithium?
At Travelocity you'll find really nice hotels in Lithium at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Lithium rather than in Lithium. We may find you even better rates, too.
How do I find the best Lithium hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Lithium then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Lithium?
The cheapest hotel in Lithium is $73. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Lithium?
There are 61 hotels in Lithium on Travelocity.
What are the best hotels in Lithium?
Lithium has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Lithium for you!
When is the best time to visit Lithium?
If you want the joy of a fun-filled trip in peak season, visit Lithium during March, May and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in Lithium?
Based on historic data is usually the cheapest month to visit Lithium. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Lithium?
There are multiple hotels in Lithium that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Lithium. We have plenty of kid-friendly hotels in Lithium to choose from on Travelocity!
Why book a hotel in Lithium through Travelocity?
Because we have the top hotels in Lithium! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Lithium on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Lithium hotel reviews by fellow wanderers

Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL

5 out of 5
Posted 12 hours ago
Travelocity Verified Review
"Nice, big building with big, comfy lobby. We were at the end of a long hallway so it was nice and private for us. Woman in charge was very pleasant and competent. Got us checked in right away."
A verified traveler stayed at Baymont by Wyndham Chester IL
Baymont by Wyndham Chester IL

Explore More Ways to Travel with Travelocity