Book Hotels in Lithium, MO

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Top Lithium hotels

Silo Farm Haus- located in the heart of wine country!

Silo Farm Haus- located in the heart of wine country!

Ste. Genevieve MO
$328 nightly
The price is $350 total per night from Apr 2 to Apr 3
$350 total
Apr 2 - Apr 3
Total with taxes and fees
This farm stay features laundry facilities.
We felt welcomed from the minute we stepped inside. My husband and I spent Valentines Day weekend touring the local wineries and rather than going out for dinner with tons of other people, we enjoyed pizza and wine at the Silo.

Reviewed on Feb 16, 2026

Opens in a new windowSilo Farm Haus- located in the heart of wine country!
"Little Brick House on Main (1865)”

"Little Brick House on Main (1865)”

Ste. Genevieve MO
$159 nightly
The price is $172 total per night from Apr 7 to Apr 8
$172 total
Apr 7 - Apr 8
Total with taxes and fees
Free WiFi in public areas is available at this vacation home.
The house was beautiful and looked like it was professionally decorated. It had all kinds of antiques and everything was deliberately placed to make the house feeling comfortable and welcoming. Would definitely recommend staying there.

Reviewed on Mar 16, 2026

Opens in a new window"Little Brick House on Main (1865)”
⚜️Rivertown Retreat⚜️ Lewis & Clark stayed here. King bed. Sleeps 4

⚜️Rivertown Retreat⚜️ Lewis & Clark stayed here. King bed. Sleeps 4

Ste. Genevieve MO
$209 nightly
The price is $227 total per night from Apr 6 to Apr 7
$227 total
Apr 6 - Apr 7
Total with taxes and fees
A garden is available at this cottage.
Lovely, thoughtfully furnished and stocked. The bed was very comfortable. The location was perfect; we were able to walk everywhere.

Reviewed on Mar 24, 2026

Opens in a new window ⚜️Rivertown Retreat⚜️ Lewis & Clark stayed here. King bed. Sleeps 4
Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

2.5 out of 5
2020 Jefferson St Perryville MO
Fully refundable
$103 nightly
The price is $118 total per night from Apr 4 to Apr 5
$118 total
Apr 4 - Apr 5
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Elevator really slow for a smaller hotel. Room was clean but in a room that slept 5-6. There were two towels provided. Pool area cramped and in need of ventilation -chlorine and heat.

Reviewed on Apr 1, 2026

Opens in a new windowHoliday Inn Express & Suites Perryville by IHG
Microtel Inn & Suites by Wyndham Sainte Genevieve

Microtel Inn & Suites by Wyndham Sainte Genevieve

2.5 out of 5
21958 Hwy 32 Ste Genevieve MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $89 total per night from Apr 5 to Apr 6
$89 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
Everything was great, enjoyed our time there

Reviewed on Mar 30, 2026

Opens in a new windowMicrotel Inn & Suites by Wyndham Sainte Genevieve
Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL

2.5 out of 5
2150 State Street Chester IL
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $83 total per night from Apr 4 to Apr 5
$83 total
Apr 4 - Apr 5
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
Breakfast was good. Love the Popeye Museum.

Reviewed on Mar 27, 2026

Opens in a new windowBaymont by Wyndham Chester IL
Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville

2 out of 5
1119 Vincent Dr Perryville MO
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $75 total per night from Apr 12 to Apr 13
$75 total
Apr 12 - Apr 13
Total with taxes and fees
This motel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Good breakfast and clean rooms.

Reviewed on Mar 28, 2026

Opens in a new windowSuper 8 by Wyndham Perryville
Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville

2 out of 5
1500 Liberty Street Perryville MO
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $77 total per night from Apr 9 to Apr 10
$77 total
Apr 9 - Apr 10
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Room was clean and comfortable. At 7am a wake up alarm played music for 45 minutes and I didn't know how to shut it off.

Reviewed on Apr 1, 2026

Opens in a new windowDays Inn by Wyndham Perryville
Quality Inn Perryville I-55

Quality Inn Perryville I-55

2.5 out of 5
1517 S. Perryville Blvd. Perryville MO
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $92 total per night from Apr 7 to Apr 8
$92 total
Apr 7 - Apr 8
Total with taxes and fees
This hotel features an outdoor pool and a gym. Enjoy the hot tub and free perks like daily breakfast and free self parking. The front desk is staffed around-the-clock ...
satisfactory

Reviewed on Mar 12, 2026

Opens in a new windowQuality Inn Perryville I-55
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Lithium?
From thoughtful amenities to more room to move, kid-friendly hotels come with features that can help turn a good family vacation into a fantastic one. These Lithium options make vacationing with young ones a piece of cake: Lost Arrowhead Lodge - Secluded - Pool - WiFi - 1 Hr South of St.Louis will help make your adventure the most memorable one yet. It features a host of nice touches, such as a swimming pool and animal viewing activities. Also look up June Bugs Loft. It offers a king bed, internet access and plenty of opportunities to spend time together.
Where can I find cheap hotels in Lithium?
At Travelocity you'll find really nice hotels in Lithium at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Lithium rather than in Lithium. We may find you even better rates, too.
How do I find the best Lithium hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Lithium then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Lithium?
The cheapest hotel in Lithium is $75. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Lithium?
There are 66 hotels in Lithium on Travelocity.
What are the best hotels in Lithium?
Lithium has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Lithium for you!
When is the best time to visit Lithium?
If you want the joy of a fun-filled trip in peak season, visit Lithium during March, May and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in Lithium?
Based on historic data is usually the cheapest month to visit Lithium. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Lithium?
There are multiple hotels in Lithium that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Lithium. We have plenty of kid-friendly hotels in Lithium to choose from on Travelocity!
Why book a hotel in Lithium through Travelocity?
Because we have the top hotels in Lithium! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Lithium on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Lithium hotel reviews by fellow wanderers

Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville

5 out of 5
Posted 3 hours ago
Travelocity Verified Review
"Room was clean and comfortable. At 7am a wake up alarm played music for 45 minutes and I didn't know how to shut it off."
A verified traveler stayed at Days Inn by Wyndham Perryville
Days Inn by Wyndham Perryville

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