Explore 35 Luxury Hotels in Key West Historic District

Name: H2O Suites - Adults Only
Price range: $471 total

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Best Luxury Hotels in Key West Historic District

The Gardens Hotel

526 Angela Street Key West FL

$299 nightly

$336 total

Dec 1 - Dec 2

Total with taxes and fees

2 outdoor pools, 2 bars/lounges, and a restaurant are among this bed & breakfast's featured amenities. Business travelers can take advantage of the free WiFi ...

9.8/10 Exceptional! (1,003 reviews)

"Best place we have stayed. The staff was amazing location perfect and the room was perfect"

Reviewed on Nov 3, 2026

The Marquesa Hotel

600 Fleming Street Key West FL

$457 nightly

$514 total

Nov 29 - Nov 30

Total with taxes and fees

This hotel features 3 outdoor pools, a restaurant, and a bar/lounge. Business travelers can take advantage of the laundry service. Self parking, a terrace, and ...

9.8/10 Exceptional! (1,001 reviews)

"The property is beautiful! The staff is great!"

Reviewed on Oct 30, 2026

Silver Palms Inn & Historic Homes

830 Truman Ave Key West FL

Fully refundableReserve now, pay when you stay

$229 nightly

$258 total

Dec 1 - Dec 2

Total with taxes and fees

An outdoor pool is featured at this hotel, along with free WiFi in public areas and luggage storage. Enjoy the free continental breakfast each morning. There's ...

9.4/10 Exceptional! (1,031 reviews)

"I enjoyed our stay until the last night. At 5pm I called the front desk to report that our rooms toilet was backed up. The lady at the front desk said that I could come down and get. A plunger. I explained ther we were out for Halloween. She then said is it clean or dirty? I told her I don't care, ..."

Reviewed on Nov 1, 2026

The Marker Key West Harbor Resort

200 William Street Key West FL

Fully refundable

$291 nightly

$327 total

Nov 29 - Nov 30

Total with taxes and fees

This smoke-free hotel features 3 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...

9.2/10 Wonderful! (1,042 reviews)

"Really nice boutique hotel with a great location, delicious food, pleasant service and lovely pool area. Will definitely return and recommend to others."

Reviewed on Nov 3, 2026

The Cabana Inn Key West - Adults Only

413 Applerouth Lane Key West FL

$235 nightly

$265 total

Nov 8 - Nov 9

Total with taxes and fees

This guesthouse features an outdoor pool and a hot tub. Enjoy the free continental breakfast each morning. Self parking, a terrace, and a garden are also ...

9/10 Wonderful! (1,004 reviews)

"Great location and friendly staff. Room size varies greatly at this inn so be sure to you understand which accommodations you are booking. The pool, hot tub and room were clean and the breakfast offerings are good. We arrived after hours to check in but called the number indicated and got our room ..."

Reviewed on Nov 3, 2026

La Concha Key West, Autograph Collection

430 Duval St Key West FL

$293 nightly

$330 total

Nov 24 - Nov 25

Total with taxes and fees

This smoke-free hotel includes 3 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express ...

8.8/10 Excellent! (511 reviews)

"It's in the CENTER OF EVERYTHING, LITERALLY!!! Great staff, good bar and food, and TRULY, it's in the best place to be cuz you can easily walk to everywhere..."

Reviewed on Nov 3, 2026

H2O Suites - Adults Only

1212 Simonton Street Key West FL

$419 nightly

$471 total

Nov 30 - Dec 1

Total with taxes and fees

This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Business travelers can take advantage of the laundry service. There's a gym on site, and ...

Duval House

815 Duval St Key West FL

$211 nightly

$234 total

Nov 29 - Nov 30

Total with taxes and fees

This bed & breakfast features a terrace, concierge services, and self parking. A garden, a picnic area, and express check-in are also on offer.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Key West Historic District

The Gardens Hotel

526 Angela Street Key West FL

$299 nightly

$336 total

Dec 1 - Dec 2

Total with taxes and fees

9.8/10 Exceptional! (1,003 reviews)

Key West Historic District Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Key West Historic District luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Key West Historic District to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Key West Historic District will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Key West Historic District, and plan your next opulent escape.

Key West Historic District hotels essential information

Accommodation	1,657 hotels
Lowest Price	$214
Highest Price	$514
Popular hotels	The Marker Key West Harbor Resort, H2O Suites - Adults Only, La Concha Key West, Autograph Collection, Silver Palms Inn & Historic Homes, Duval House, The Cabana Inn Key West - Adults Only, The Gardens Hotel, The Marquesa Hotel