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Top Dupo hotels

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
The price is $106 total per night from May 3 to May 4
$106 total
per night
May 3 - May 4
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
Upon arriving at the property, we were told we were at the wrong property. I didn't realize there were 2. Stephanie proceeded to switch the reservation so we wouldn't have to go across town after driving 8 hours already. I think she was sent from Heaven. We were pleasantly surprised to hear there ...

Reviewed on Apr 22, 2026

Opens in a new windowPear Tree Inn St. Louis Airport
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $189 total per night from May 3 to May 4
$189 total
per night
May 3 - May 4
2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...
Overall, a great value for the price. I would absolutely stay there again. Perfectly located. Easy to find. Incredible staff. The breakfast ladies are the best. I'm not a morning person & I left smiling every morning. Good food. Evening appetizers were easily a meal. We enjoyed visiting with other ...

Reviewed on Apr 21, 2026

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
The price is $189 total per night from May 10 to May 11
$189 total
per night
May 10 - May 11
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
Perfectly located

Reviewed on Apr 20, 2026

Opens in a new windowLive by Loews - St.Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $116 total per night from May 3 to May 4
$116 total
per night
May 3 - May 4
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Parking was secure and convenient. Breakfast was great!

Reviewed on Apr 22, 2026

Opens in a new windowClayton Plaza Hotel & Extended Stay
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $173 total per night from May 24 to May 25
$173 total
per night
May 24 - May 25
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
The staff was great and willing to help. They even ran my uber eats up to my room and new key cards. This hotel will be my go-to when back in St. Louis.

Reviewed on Apr 22, 2026

Opens in a new window21C Museum Hotel St Louis
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

2.5 out of 5
333 Washington Ave St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $143 total per night from May 3 to May 4
$143 total
per night
May 3 - May 4
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Staff was super friendly. I felt safe there. It just is a very old building and it wasn’t extremely clean and it was kind of annoying because they were letting somebody play loud music in the lobby when we were checking in on their phone. The breakfast was just OK. It was worth it for the price. ...

Reviewed on Apr 23, 2026

Opens in a new windowHampton Inn St. Louis-Downtown (At the Gateway Arch)
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $161 total per night from May 8 to May 9
$161 total
per night
May 8 - May 9
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
Great location

Reviewed on Apr 20, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
The price is $103 total per night from May 17 to May 18
$103 total
per night
May 17 - May 18
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Room was clean but mold in Soap dispenser in bathroom should’ve been replaced before room was sold.

Reviewed on Apr 22, 2026

Opens in a new windowHeritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $143 total per night from May 8 to May 9
$143 total
per night
May 8 - May 9
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
Opens in a new windowRenaissance St. Louis Airport Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Dupo Hotel & Travel Guide\n

Finally taking that trip and looking for hotels in the heart of Dupo? Dupo lists 3 hotels within 6 miles (10 kilometers) of the downtown area.

The Comfort Inn & Suites Cahokia is the nearest to the center of Dupo and the only option just a short drive away.

8 miles (13 kilometers) away from central Dupo, you can find the Four Seasons Hotel St Louis. The The Ritz-Carlton, St. Louis can be found 11 miles (18 kilometers) away. Another option is to book the Grand Center Inn or the The Chase Park Plaza.

After you and your traveling partner have found all the secrets of Dupo, how about you tour a little further afield? The Southern Illinois area is home to lots of places to discover. Move around Southern Illinois's farms. Those drawn to nature can also make the time to admire the region's rural landscapes, rolling hills and prairies. Popular pastimes in this particular region of United States of America include rock climbing.

30 miles (48 kilometers) from Dupo, you'll reach Alton, where you can spend the day enjoying Argosy Casino and Alton Square Mall. The Atrium Hotel and Conference Center and Comfort Inn are just a handful of the Travelocity hotel and apartment alternatives in Alton. 12 miles (20 kilometers) northeast of Dupo, you will reach Fairview Heights, which features the Holiday Inn St. Louis Fairview Heights and Fairfield Inn by Marriott Fairview Heights. The Stonewolf Golf Course and St. Claire Square Mall are more popular places to discover when you're in Fairview Heights.

If watching stadium sport is the love of your life, pay a visit to Busch Stadium, located 8 miles (12 kilometers) to the north of Dupo. Book Travelocity-listed accommodation nearby to the action at the The Westin St. Louis or the Embassy Suites St. Louis - Downtown.

If you're traveling through Lambert-St. Louis International Airport and want to find somewhere to stay nearby, try Marriott St. Louis Airport or Holiday Inn St. Louis-Airport.

Frequently asked questions

What are the top kid-friendly hotels in Dupo?
Take some of the troubles out of traveling with young ones by booking a family-friendly hotel in Dupo. From entertaining amenities to services that bring a smile, these properties offer perks that'll make your visit an effortless one: You'll be well looked after at Quality Inn & Suites near St. Louis and I-255. It comes with complimentary breakfast, pet-friendly facilities and a knack for making families feel welcome. Also consider staying at Comfortable home if your visiting the St. Louis area for work or play. It comes with a king bed, pet-friendly facilities and lots of opportunities for precious family time.
Where can I find cheap hotels in Dupo?
At Travelocity you'll find really nice hotels in Dupo at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Dupo rather than in Dupo. We may find you even better rates, too.
How do I find the best Dupo hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Dupo then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Dupo?
The cheapest hotel in Dupo is $103. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Dupo?
There are 1,715 hotels in Dupo on Travelocity.
What are the best hotels in Dupo?
Dupo has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Dupo for you!
When is the best time to visit Dupo?
If you want the joy of a fun-filled trip in peak season, visit Dupo during March, May and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Dupo?
Based on historic data is usually the cheapest month to visit Dupo. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Dupo?
There are multiple hotels in Dupo that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Dupo. We have plenty of kid-friendly hotels in Dupo to choose from on Travelocity!
Why book a hotel in Dupo through Travelocity?
Because we have the top hotels in Dupo! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Dupo on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

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