Book Hotels in Clarksdale, MO
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Top Clarksdale hotels

Drury Inn & Suites St Joseph
4213 Frederick Ave St. Joseph MO
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $127 total per night from Jun 14 to Jun 15
$127 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"The rooms were clean. Beds comfortable. Breakfast and happy hour were great!"
Reviewed on Jun 5, 2026

My Place Hotel St Joseph MO
3621 N Village Dr St. Joseph MO
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $100 total per night from Jun 7 to Jun 8
$100 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the 24-hour business center. ...
"Bed was comfy"
Reviewed on Jun 5, 2026

Home2 Suites By Hilton St. Joseph
3701 North Village Drive St. Joseph MO
$114 nightly
The price is $132 total per night from Jun 14 to Jun 15
$132 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Business travelers can take advantage of the business center. Guests will appreciate freebies like ...
"Had to wait a long time for check-in due to a computer problem that was causing overbooking of rooms. Did not like that the dishes for breakfast were ALL glass/ceramic so that patrons could not take anything from the breakfast area."
Reviewed on Jun 4, 2026

Stoney Creek Hotel St. Joseph
1201 N Woobine Rd St. Joseph MO
Fully refundableReserve now, pay when you stay
$121 nightly
The price is $140 total per night from Jun 7 to Jun 8
$140 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
"We only stayed one night. Wish we could have stayed longer this place is beautiful and the staff is amazing"
Reviewed on Jun 6, 2026

Red Roof Inn Cameron
501 Northland Drive Cameron MO
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $105 total per night from Jun 14 to Jun 15
$105 total
Jun 14 - Jun 15
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like continental breakfast and WiFi ...
"Good location. Did not have good street appeal."
Reviewed on Jun 5, 2026

Quality Inn Cameron
1803 Comfort Ln Cameron MO
Fully refundable
$117 nightly
The price is $130 total per night from Jul 5 to Jul 6
$130 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free buffet breakfast each morning. A computer station, luggage ...
"Clean, Brwakfast was really good."
Reviewed on May 10, 2026

Hampton Inn St. Joseph
3928 Frederick Ave St. Joseph MO
Fully refundableReserve now, pay when you stay
$37 nightly
The price is $43 total per night from Jun 28 to Jun 29
$43 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
"The hotel is a 5 out of 10. Very dated, not Hilton quality. Hilton has lowered their standards and Expedia also has lowered their expectations. Makes a person wonder who to use choosing a hotel."
Reviewed on Jun 4, 2026

SureStay Hotel by Best Western Cameron
2210 US Highway 36 Cameron MO
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Staff at the 24-hour front desk can provide ...
"The staff was friendly enough. I've NEVER had a flyswatter hanging on a thumbtack in a room before. We killed 4 flies. The curtains didn't have enough hooks, so they couldn't completely close. I used a hair clip to secure them. I hope that the spots on the wall was over spray from a soda and not ..."
Reviewed on Jun 1, 2026

AmeriStay Inn
4502 SE US HWY 169 St. Joseph MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $93 total per night from Jun 22 to Jun 23
$93 total
Jun 22 - Jun 23
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. Express check-out, ...
"The security lock on the door was broken, turned on TV had a picture turned off to go out to eat but when we returned NO picture but sound. Was told having issues with cable?.. Where you hang your clothes on was coming out of the wall. No clock in room, no kleenex box, the outlets on the lamp was ..."
Reviewed on Jun 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Clarksdale hotel reviews by fellow wanderers

Stoney Creek Hotel St. Joseph
5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"We only stayed one night. Wish we could have stayed longer this place is beautiful and the staff is amazing"
A verified traveler stayed at Stoney Creek Hotel St. Joseph
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