Book Hotels in Clarksdale, MO

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Top Clarksdale hotels

Drury Inn & Suites St Joseph

Drury Inn & Suites St Joseph

3 out of 5
4213 Frederick Ave St. Joseph MO
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $127 total per night from Jul 26 to Jul 27
$127 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"Staff was friendly and helpful. The hotel was nice and clean. Our room was clean and comfortable. Breakfast was good. The food was displayed nice. Nice variety. Coffee was hot. I would stay again and recommend."

Reviewed on Jul 22, 2026

Opens in a new windowDrury Inn & Suites St Joseph
Holiday Inn Express Hotel & Suites St. Joseph by IHG

Holiday Inn Express Hotel & Suites St. Joseph by IHG

2.5 out of 5
3600 N. Village Dr. St. Joseph MO
Fully refundable
$89 nightly
The price is $103 total per night from Aug 16 to Aug 17
$103 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Breakfast was excellent"

Reviewed on Jul 19, 2026

Opens in a new windowHoliday Inn Express Hotel & Suites St. Joseph by IHG
Red Roof Inn Cameron

Red Roof Inn Cameron

2 out of 5
501 Northland Drive Cameron MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $104 total per night from Jul 26 to Jul 27
$104 total
Jul 26 - Jul 27
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like continental breakfast and WiFi ...
"Greeted with friendly faces and conversations. Very clean place."

Reviewed on Jul 20, 2026

Opens in a new windowRed Roof Inn Cameron
Hampton Inn St. Joseph

Hampton Inn St. Joseph

2.5 out of 5
3928 Frederick Ave St. Joseph MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $103 total per night from Aug 16 to Aug 17
$103 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
"Good location with shopping and restaurants nearby."

Reviewed on Jul 21, 2026

Opens in a new windowHampton Inn St. Joseph
Stoney Creek Hotel St. Joseph

Stoney Creek Hotel St. Joseph

3.5 out of 5
1201 N Woobine Rd St. Joseph MO
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $138 total per night from Jul 26 to Jul 27
$138 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
Opens in a new windowStoney Creek Hotel St. Joseph
My Place Hotel St Joseph MO

My Place Hotel St Joseph MO

2 out of 5
3621 N Village Dr St. Joseph MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $103 total per night from Aug 16 to Aug 17
$103 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the 24-hour business center. ...
Opens in a new windowMy Place Hotel St Joseph MO
SureStay Hotel by Best Western Cameron

SureStay Hotel by Best Western Cameron

2.5 out of 5
2210 US Highway 36 Cameron MO
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $86 total per night from Jul 28 to Jul 29
$86 total
Jul 28 - Jul 29
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Staff at the 24-hour front desk can provide ...
Opens in a new windowSureStay Hotel by Best Western Cameron
Home2 Suites By Hilton St. Joseph

Home2 Suites By Hilton St. Joseph

3 out of 5
3701 North Village Drive St. Joseph MO
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $118 total per night from Aug 2 to Aug 3
$118 total
Aug 2 - Aug 3
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Business travelers can take advantage of the business center. Guests will appreciate freebies like ...
Opens in a new windowHome2 Suites By Hilton St. Joseph
Quality Inn Cameron

Quality Inn Cameron

2.5 out of 5
1803 Comfort Ln Cameron MO
Fully refundable
$105 nightly
The price is $117 total per night from Aug 21 to Aug 22
$117 total
Aug 21 - Aug 22
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free buffet breakfast each morning. A computer station, luggage ...
Opens in a new windowQuality Inn Cameron
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Clarksdale?
Family trips are where amazing memories are made, but it's no secret that traveling with young ones can be daunting. These kid-friendly Clarksdale hotels come with perks that aim to keep guests of all ages comfortable and happy: Cozy Country Farm house, 12 minutes from I-35 will help make your next trip the most memorable one yet. It features a variety of conveniences geared toward families, such as a barbecue grill and a fridge. Econo Lodge Cameron is another top place to stay. After a fun day of exploring, come home to your cozy room and amenities like complimentary breakfast and a picnic area.
Where can I find cheap hotels in Clarksdale?
At Travelocity you'll find really nice hotels in Clarksdale at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Clarksdale rather than in Clarksdale. We may find you even better rates, too.
How do I find the best Clarksdale hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Clarksdale then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Clarksdale?
The cheapest hotel in Clarksdale is $86. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Clarksdale?
There are 158 hotels in Clarksdale on Travelocity.
What are the best hotels in Clarksdale?
Clarksdale has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Clarksdale for you!
When is the best time to visit Clarksdale?
If you want the joy of a fun-filled trip in peak season, visit Clarksdale during March, June and July. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, April and December.
When is the cheapest time to stay in Clarksdale?
Based on historic data is usually the cheapest month to visit Clarksdale. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Clarksdale?
There are multiple hotels in Clarksdale that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Clarksdale. We have plenty of kid-friendly hotels in Clarksdale to choose from on Travelocity!
Why book a hotel in Clarksdale through Travelocity?
Because we have the top hotels in Clarksdale! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Clarksdale on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Clarksdale hotel reviews by fellow wanderers

Drury Inn & Suites St Joseph

Drury Inn & Suites St Joseph

5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"Staff was friendly and helpful. The hotel was nice and clean. Our room was clean and comfortable. Breakfast was good. The food was displayed nice. Nice variety. Coffee was hot. I would stay again and recommend."
A verified traveler stayed at Drury Inn & Suites St Joseph
Drury Inn & Suites St Joseph

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