Book Hotels in Clarksdale, MO
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Top Clarksdale hotels

Fairfield Inn & Suites by Marriott St. Joseph
4779 Tuscany Drive St. Joseph MO
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $133 total per night from Dec 19 to Dec 20
$133 total
Dec 19 - Dec 20
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the free ...
The hotel was nice and seemed newer. Breakfast had great options for all. We weren't thrilled about the flies and Asian beetles that somehow were in our room when we arrived. There was a beam in the suite that creates a doorway/separation from the sitting area and sleeping area that was absolutely ...
Reviewed on Nov 12, 2025

Drury Inn & Suites St Joseph
4213 Frederick Ave St. Joseph MO
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $116 total per night from Dec 12 to Dec 13
$116 total
Dec 12 - Dec 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Friendly staff, clean ro
Reviewed on Dec 1, 2025

Stoney Creek Hotel St. Joseph
1201 N Woobine Rd St. Joseph MO
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $123 total per night from Dec 9 to Dec 10
$123 total
Dec 9 - Dec 10
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
Wonderful place will definitely stay here again
Reviewed on Dec 5, 2025

My Place Hotel St Joseph MO
3621 N Village Dr St. Joseph MO
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $83 total per night from Dec 28 to Dec 29
$83 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the 24-hour business center. ...
Nice room
Reviewed on Nov 30, 2025

Holiday Inn Express Hotel & Suites St. Joseph by IHG
3600 N. Village Dr. St. Joseph MO
Fully refundable
$97 nightly
The price is $112 total per night from Dec 13 to Dec 14
$112 total
Dec 13 - Dec 14
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Staff not very friendly
Reviewed on Dec 1, 2025

Ant’s Waterfront 2 Bdrm Cabin w/ Best Sunset View!
Saint Joseph MO
$145 nightly
The price is $161 total per night from Dec 15 to Dec 16
$161 total
Dec 15 - Dec 16
Total with taxes and fees
This cabin features a garden, laundry facilities, and barbecue grills.
Enjoyed our stay
Reviewed on Oct 19, 2025

Red Roof Inn Cameron
501 Northland Drive Cameron MO
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $97 total per night from Dec 8 to Dec 9
$97 total
Dec 8 - Dec 9
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like continental breakfast and WiFi ...
Friendly staff, very clean room. Close to restaurants. Glad this room was booked.
Reviewed on Dec 2, 2025

Hampton Inn St. Joseph
3928 Frederick Ave St. Joseph MO
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $101 total per night from Dec 14 to Dec 15
$101 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
The young man who checked us in was friendly and welcoming. When we got to our room it was spotless. Very good breakfast next day. Friendly staff in the dining room. Would stay here again.
Reviewed on Nov 29, 2025

Days Inn by Wyndham Cameron
601 E. Bryan Road Cameron MO
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $74 total per night from Dec 29 to Dec 30
$74 total
Dec 29 - Dec 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
Breakfast was good,they were outta eggd let front desk know and they refilled it promptly...
Reviewed on Nov 22, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Clarksdale hotel reviews by fellow wanderers

Stoney Creek Hotel St. Joseph
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Wonderful place will definitely stay here again "
A verified traveler from Goodman stayed at Stoney Creek Hotel St. Joseph
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