Explore top 2026 5 Star Hotels in Otay Mesa West
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Top Otay Mesa West 5 Star hotels

Pendry San Diego
550 J Street San Diego CA
Fully refundableReserve now, pay when you stay
$340 nightly
The price is $395 total per night from Jan 5 to Jan 6
$395 total
Jan 5 - Jan 6
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,003 reviews)
The room was clean, tasteful, and quiet. The staff was very friendly and helpful. We had a wonderful time in Pendry.
Reviewed on Jan 1, 2026

The US Grant, a Luxury Collection Hotel, San Diego
326 Broadway San Diego CA
Fully refundableReserve now, pay when you stay
$271 nightly
The price is $315 total per night from Jan 9 to Jan 10
$315 total
Jan 9 - Jan 10
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...
9/10 Wonderful! (1,000 reviews)
Classic beautiful hotel
Reviewed on Dec 19, 2025

Shore House at The Del, LXR Hotels & Resorts
1500 Orange Avenue Coronado CA
$619 nightly
The price is $687 total per night from Jan 11 to Jan 12
$687 total
Jan 11 - Jan 12
Total with taxes and fees
A private beach, 7 restaurants, and 2 outdoor pools are all featured at this luxury resort. Relax with beach cabanas and sun loungers, and cool off with a drink ...
9.2/10 Wonderful! (118 reviews)
Luxurious
Reviewed on Dec 29, 2025

Beach Village at The Del, LXR Hotels & Resorts
1500 Orange Avenue Coronado CA
$783 nightly
The price is $863 total per night from Jan 18 to Jan 19
$863 total
Jan 18 - Jan 19
Total with taxes and fees
A private beach, 7 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy beachfront dining and relax with beach cabanas and sun ...
9/10 Wonderful! (122 reviews)
Great experience! Wonderful staff
Reviewed on Dec 9, 2025

The Bower Coronado
1417 Orange Ave Coronado CA
Fully refundableReserve now, pay when you stay
$279 nightly
The price is $302 total per night from Jan 5 to Jan 6
$302 total
Jan 5 - Jan 6
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
9.2/10 Wonderful! (156 reviews)
No breakfast was offered.The location could not be beat. The staff were so friendly and knowledge.
Reviewed on Dec 29, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Otay Mesa West hotel reviews by fellow wanderers

Sheraton San Diego Resort
5 out of 5
Posted 18 hours ago
Travelocity Verified Review
"Great "
A verified traveler stayed at Sheraton San Diego Resort
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