Explore top 2026 5 Star Hotels in Otay Mesa West
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Top Otay Mesa West 5 Star hotels

Pendry San Diego
550 J Street San Diego CA
Fully refundableReserve now, pay when you stay
$342 nightly
The price is $397 total per night from Apr 6 to Apr 7
$397 total
Apr 6 - Apr 7
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,003 reviews)
Excellent, extended my stay.
Reviewed on Mar 15, 2026

The US Grant, a Luxury Collection Hotel, San Diego
326 Broadway San Diego CA
Fully refundableReserve now, pay when you stay
$294 nightly
The price is $341 total per night from Apr 5 to Apr 6
$341 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...
9/10 Wonderful! (1,003 reviews)
Wonderful hotel and staff. Greatest stay ever.
Reviewed on Mar 13, 2026

The Bower Coronado
1417 Orange Ave Coronado CA
Fully refundableReserve now, pay when you stay
$349 nightly
The price is $385 total per night from Apr 5 to Apr 6
$385 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
9.2/10 Wonderful! (191 reviews)
This property is fantastic. I would recommend to anyone I know. It is a great location with amazing staff and the property is stunning. Feels like a very fancy home away from home.
Reviewed on Mar 10, 2026

Shore House at The Del, LXR Hotels & Resorts
1500 Orange Avenue Coronado CA
$605 nightly
The price is $672 total per night from Apr 13 to Apr 14
$672 total
Apr 13 - Apr 14
Total with taxes and fees
A private beach, 7 restaurants, and 2 outdoor pools are all featured at this luxury resort. Relax with beach cabanas and sun loungers, and cool off with a drink ...
9.2/10 Wonderful! (130 reviews)
EVERYTHING!!!! Although parking price if $79.00 a day is a little steep and was not lisywd when i made reservation
Reviewed on Mar 2, 2026

Beach Village at The Del, LXR Hotels & Resorts
1500 Orange Avenue Coronado CA
$765 nightly
The price is $842 total per night from Apr 12 to Apr 13
$842 total
Apr 12 - Apr 13
Total with taxes and fees
A private beach, 7 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy beachfront dining and relax with beach cabanas and sun ...
9.2/10 Wonderful! (130 reviews)
The room was perfect and we had a direct view of the beach and ocean. We are looking forward to our next stay.
Reviewed on Mar 15, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Otay Mesa West hotel reviews by fellow wanderers

Paradise Point Resort & Spa
5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Beautiful resort great customer service. I would highly recommend staying here."
A verified traveler stayed at Paradise Point Resort & Spa
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