Explore top 2026 5 Star Hotels in Otay Mesa West
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Top Otay Mesa West 5 Star hotels

Pendry San Diego
550 J Street San Diego CA
$342 nightly
The price is $397 total per night from Jun 7 to Jun 8
$397 total
Jun 7 - Jun 8
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,005 reviews)
Cathy In concierge was exceptional.
Reviewed on May 11, 2026

The US Grant, a Luxury Collection Hotel, San Diego
326 Broadway San Diego CA
Fully refundableReserve now, pay when you stay
$247 nightly
The price is $287 total per night from May 31 to Jun 1
$287 total
May 31 - Jun 1
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...
9/10 Wonderful! (1,001 reviews)
The MOST COMFORTABLE BED I’ve ever slept in. We will definitely be back!!!
Reviewed on May 10, 2026

Shore House at The Del, LXR Hotels & Resorts
1500 Orange Avenue Coronado CA
$812 nightly
The price is $901 total per night from May 24 to May 25
$901 total
May 24 - May 25
Total with taxes and fees
A private beach, 7 restaurants, and 2 outdoor pools are all featured at this luxury resort. Relax with beach cabanas and sun loungers, and cool off with a drink ...
9.2/10 Wonderful! (147 reviews)
Perfect view of the ocean! The room was very clean! The grounds are absolutely beautiful!
Reviewed on May 15, 2026

The Bower Coronado
1417 Orange Ave Coronado CA
Fully refundableReserve now, pay when you stay
$349 nightly
The price is $385 total per night from May 25 to May 26
$385 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
9.2/10 Wonderful! (232 reviews)
Nice staff, was pretty quite here all things considered
Reviewed on May 15, 2026

Beach Village at The Del, LXR Hotels & Resorts
1500 Orange Avenue Coronado CA
$952 nightly
The price is $1,047 total per night from May 25 to May 26
$1,047 total
May 25 - May 26
Total with taxes and fees
A private beach, 7 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy beachfront dining and relax with beach cabanas and sun ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Otay Mesa West hotel reviews by fellow wanderers

Sheraton San Diego Resort
4 out of 5
Posted 1 hour ago
Travelocity Verified Review
"The coffee maker pods did not fit the coffee maker in our room so we could not make coffee!
The shower switch that moves water flow from the shower head to the hand held device did not work. It was corroded probably due to
excessive minerals in the water."
A verified traveler stayed at Sheraton San Diego Resort
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