Explore top 2026 5 Star Hotels in Otay Mesa West
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top Otay Mesa West 5 Star hotels

Pendry San Diego
550 J Street San Diego CA
$342 nightly
The price is $397 total per night from Jun 3 to Jun 4
$397 total
Jun 3 - Jun 4
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,000 reviews)
Cathy In concierge was exceptional.
Reviewed on May 11, 2026

The US Grant, a Luxury Collection Hotel, San Diego
326 Broadway San Diego CA
Fully refundableReserve now, pay when you stay
$239 nightly
The price is $278 total per night from May 25 to May 26
$278 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...
9/10 Wonderful! (1,000 reviews)
The MOST COMFORTABLE BED I’ve ever slept in. We will definitely be back!!!
Reviewed on May 10, 2026

Shore House at The Del, LXR Hotels & Resorts
1500 Orange Avenue Coronado CA
$714 nightly
The price is $792 total per night from May 19 to May 20
$792 total
May 19 - May 20
Total with taxes and fees
A private beach, 7 restaurants, and 2 outdoor pools are all featured at this luxury resort. Relax with beach cabanas and sun loungers, and cool off with a drink ...
9.2/10 Wonderful! (146 reviews)
Professional and attentive staff.
Reviewed on May 12, 2026

The Bower Coronado
1417 Orange Ave Coronado CA
Fully refundableReserve now, pay when you stay
$349 nightly
The price is $385 total per night from May 25 to May 26
$385 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
9.2/10 Wonderful! (228 reviews)
Great hotel choice. modern, comfortable,new and clean. great location right next across the street from the Del Coronado. Friendly and helpful staff
Reviewed on May 13, 2026

Beach Village at The Del, LXR Hotels & Resorts
1500 Orange Avenue Coronado CA
$930 nightly
The price is $1,023 total per night from May 18 to May 19
$1,023 total
May 18 - May 19
Total with taxes and fees
A private beach, 7 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy beachfront dining and relax with beach cabanas and sun ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Otay Mesa West hotel reviews by fellow wanderers

Wyndham San Diego Bayside
2 out of 5
Posted 2 hours ago
Travelocity Verified Review
"The room was not as cleanly as I had hoped. The shower particularly. The floor of the shower was slimy which was really disturbing. I was scared that I’d pick up some disease on my feet.
There was no kleenex in the tissue dispenser
The elevator smelled less than fresh"
A verified traveler stayed at Wyndham San Diego Bayside
More ways to wander Otay Mesa West
Explore More Ways to Travel with Travelocity
- Apartments in Iris Avenue Trolley Station
- Condos in Iris Avenue Trolley Station
- Guest Houses in Iris Avenue Trolley Station
- Hotels near Iris Avenue Trolley Station
- 3 Star Hotels in Chula Vista
- 4 Star Hotels in Chula Vista
- 5 Star Hotels in Chula Vista
- 3 Star Hotels in National City
- B&B in San Ysidro
- Cabins in San Ysidro
- Condos in San Ysidro
- Cottages in San Ysidro
- Extended Stay Hotels in San Ysidro
- Guest Houses in San Ysidro
- Hostels in San Ysidro
- Beach Resorts & in San Ysidro
- Casino Resorts & in San Ysidro
- Cheap Hotels in San Ysidro
- Convention Center Hotels in San Ysidro
- Kid Friendly Hotels in San Ysidro
- Hotels with Airport Transfers in San Ysidro
- Hotels with Free Airport Shuttle in San Ysidro
- Hotels with Free Parking in San Ysidro
- Hotels with Hot Tubs in San Ysidro
- La Quinta Inn & Suites Hotels in San Ysidro
- Luxury Hotels in San Ysidro
- Oakwood Hotels in San Ysidro
- Pet Friendly Hotels in San Ysidro
- Spa Resorts & in San Ysidro
- Vagabond Inn Hotels in San Ysidro
- San Ysidro Hotels
- Motels in San Ysidro
- Rv Parks in San Ysidro
- Resorts in San Ysidro
- Hotels near Kaiser Permanente Otay Mesa Medical Offices
- 2 Star Hotels in Normal Heights
- 5 Star Hotels in San Diego Coast
- 4 Star Hotels in Otay
- Golf Resorts & in Otay
- Hotels with Pools in Otay
- Spa Resorts & in Otay
- Otay Hotels
- Hotels near San Ysidro Border Crossing
- Hotels near Sesame Place San Diego
- Hotels near San Ysidro Transit Center Station
- Apartments in Beyer Blvd Trolley Station
- Hotels near Beyer Blvd Trolley Station
- 3 Star Hotels in Hillcrest
- 4 Star Hotels in Hillcrest
- Golf Resorts & in Castle Park
- 4 Star Hotels in Otay Mesa
- 5 Star Hotels in Otay Mesa
- Beach Resorts & in Ocean View Hills
- Luxury Hotels in Ocean View Hills
- Spa Resorts & in Ocean View Hills
- Ocean View Hills Hotels
- 5 Star Hotels in Encanto
- 3 Star Hotels in San Diego
- 4 Star Hotels in San Diego
- 5 Star Hotels in San Diego
- Hotels near Las Americas Premium Outlets
- Motels in Palomar St Trolley Station
- 5 Star Hotels in Coronado
- 4 Star Hotels in Imperial Beach
- Arcade Hotels in South San Diego
- Extended Stay America Hotels in South San Diego
- Pet Friendly Hotels in South San Diego
- Romantic Getaways & Hotels in South San Diego
- Waterpark Hotels and Resorts in South San Diego
- South San Diego Hotels
- Rv Parks in South San Diego
- Hotels near Palm Ave Trolley Station
- Houseboats in Palm Ave Trolley Station
- Motels in Palm Ave Trolley Station
- Palm City Hotels
- 4 Star Hotels in North Park
- 3 Star Hotels in Downtown San Diego
- 2 Star Hotels in Asian Pacific Thematic Historic District
- 3 Star Hotels in Golden Hill
- 5 Star Hotels in Golden Hill
- 4 Star Hotels in Little Italy
- 4 Star Hotels in Spring Valley
- 5 Star Hotels in Spring Valley
- 4 Star Hotels in Point Loma
- 3 Star Hotels in Gaslamp Quarter
- 4 Star Hotels in Gaslamp Quarter
- 5 Star Hotels in Gaslamp Quarter
- 3 Star Hotels in Coronado Island





