Explore top 2026 4 Star Hotels in Southern Indiana

Name: Louisville Marriott Downtown
Price range: $197 total
Rating: 9

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Top Southern Indiana 4 Star hotels

Galt House Hotel Trademark Collection by Wyndham

140 North Fourth Street Louisville KY

Fully refundableReserve now, pay when you stay

$119 nightly

$140 total

Jun 28 - Jun 29

Total with taxes and fees

A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

9/10 Wonderful! (4,194 reviews)

"Nice place to stay."

Reviewed on Jun 12, 2026

Omni Louisville Hotel

400 S. 2nd Street Louisville KY

Fully refundableReserve now, pay when you stay

$159 nightly

$187 total

Jun 28 - Jun 29

Total with taxes and fees

A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

9.4/10 Exceptional! (1,931 reviews)

"Pool, hot tub amazing and enough space for guests. Work out gym great options for everyone. Ideal location and market, restaurants and bowling on site was perfect!"

Reviewed on Jun 12, 2026

Embassy Suites Louisville Downtown

501 South Fourth Street Louisville KY

Fully refundableReserve now, pay when you stay

$112 nightly

$132 total

Jun 29 - Jun 30

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and a roundtrip airport shuttle. ...

9/10 Wonderful! (1,264 reviews)

"Huge renovated rooms and bathrooms. Connected to cvs and right downtown. Tv seemed to be broken but I survived one night just fine without."

Reviewed on Jun 11, 2026

21c Museum Hotel Louisville

700 W Main Street Louisville KY

Fully refundableReserve now, pay when you stay

$156 nightly

$184 total

Jul 3 - Jul 4

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9.4/10 Exceptional! (1,001 reviews)

"Loved this hotel and museum. Really enjoyed leisurely walking the museum with a bourbon in hand!"

Reviewed on Jun 7, 2026

The Brown Hotel

335 W Broadway Louisville KY

Fully refundableReserve now, pay when you stay

$163 nightly

$192 total

Jun 28 - Jun 29

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...

9.4/10 Exceptional! (1,252 reviews)

"Rooms were very comfortable and quiet. Furnishings are a little dated. Restaurant staff was very friendly and did try the Brown for dinner.. Yum!! Derby pie was great too!! Parking is in adjacent lot with hallway to access hotel straight to front desk."

Reviewed on Jun 12, 2026

Hyatt Regency Louisville

320 West Jefferson Street Louisville KY

Fully refundableReserve now, pay when you stay

$151 nightly

$178 total

Jun 28 - Jun 29

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

8.8/10 Excellent! (1,007 reviews)

"Great location and easy parking. The staff was very friendly as well."

Reviewed on Jun 11, 2026

Hotel Genevieve part of JdV by Hyatt

730 E Market St Louisville KY

Fully refundableReserve now, pay when you stay

$135 nightly

$159 total

Jun 28 - Jun 29

Total with taxes and fees

This hotel features a restaurant and 2 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a snack bar/deli are also offered.

9.2/10 Wonderful! (1,106 reviews)

"It was a lovely stay."

Reviewed on Jun 11, 2026

Hotel Distil, Autograph Collection

101 West Main Street Louisville KY

$193 nightly

$227 total

Jul 3 - Jul 4

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...

9.6/10 Exceptional! (471 reviews)

"Great experience. Walkable loved it"

Reviewed on Jun 8, 2026

The Grady

601 W Main St Louisville KY

Fully refundableReserve now, pay when you stay

$167 nightly

$197 total

Jun 26 - Jun 27

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a coffee shop, and a library are also offered.

9.4/10 Exceptional! (1,012 reviews)

"Parking is valet or a block away that needs to be paid ahead. Would have been nice to know ahead of time."

Reviewed on Jun 9, 2026

Louisville Marriott Downtown

280 West Jefferson Street Louisville KY

Fully refundableReserve now, pay when you stay

$168 nightly

$197 total

Jun 28 - Jun 29

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9/10 Wonderful! (1,000 reviews)

"Excellent customer service. Centrally located."

Reviewed on Jun 1, 2026

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4 Star Hotels Southern Indiana

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Southern Indiana 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Southern Indiana will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Southern Indiana, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.