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Top Madison 4 Star hotels

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$141 nightly
The price is $167 total per night from Jun 12 to Jun 13
$167 total
Jun 12 - Jun 13
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
8.6/10 Excellent! (4,073 reviews)
"The hotel staff is the friendliest I have ever experienced."

Reviewed on Jun 2, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Jun 28 to Jun 29
$158 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
Opens in a new windowRenaissance St. Louis Airport Hotel
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
$156 nightly
The price is $183 total per night from Jun 14 to Jun 15
$183 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,878 reviews)
"Gorgeous, clean, unique, and within walking distance of everything fun! Valets were so helpful and friendly, right off the bat. They set an excellent first impression. The hotel alone provided a fantastic experience with the art exhibit and the main floor entertainment options. The gym area was the ..."

Reviewed on Jun 3, 2026

Opens in a new window21C Museum Hotel St Louis
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $189 total per night from Jun 21 to Jun 22
$189 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9.4/10 Exceptional! (1,201 reviews)
"Everything was wonderful"

Reviewed on Jun 2, 2026

Opens in a new windowLive by Loews - St.Louis
River City Casino & Hotel

River City Casino & Hotel

4 out of 5
777 River City Casino Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $107 total per night from Jun 8 to Jun 9
$107 total
Jun 8 - Jun 9
Total with taxes and fees
This hotel features a casino, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the business center, conference center, and conference ...
9/10 Wonderful! (1,592 reviews)
"Everything was great"

Reviewed on Jun 2, 2026

Opens in a new windowRiver City Casino & Hotel
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $155 total per night from Jun 28 to Jun 29
$155 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.8/10 Excellent! (1,287 reviews)
"Great place! Super comfortable"

Reviewed on Jun 2, 2026

Opens in a new windowMagnolia Hotel St. Louis, a Tribute Portfolio Hotel
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$209 nightly
The price is $246 total per night from Jun 14 to Jun 15
$246 total
Jun 14 - Jun 15
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
9/10 Wonderful! (1,006 reviews)
"Very nice all around, staff was very friendly and helpful, the rooms was clean, the hotel was beautiful"

Reviewed on Jun 1, 2026

Opens in a new window The Royal Sonesta Chase Park Plaza St. Louis
Hilton St. Louis Frontenac

Hilton St. Louis Frontenac

4 out of 5
1335 S Lindbergh Blvd Frontenac MO
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $157 total per night from Jun 21 to Jun 22
$157 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.8/10 Excellent! (1,000 reviews)
"Great location for us, all the staff were very helpful and friendly. Breakfast was different to what we are use to in the UK and Europe, but it was still really good, plenty to choose from and our kids loved it. Parking was close to the room, which was great cause we had lots of bags. Definitely ..."

Reviewed on Jun 2, 2026

Opens in a new windowHilton St. Louis Frontenac
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

4 out of 5
1820 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $169 total per night from Jun 20 to Jun 21
$169 total
Jun 20 - Jun 21
Total with taxes and fees
This luxury hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free WiFi. ...
Opens in a new windowSt. Louis Union Station Hotel, Curio Collection by Hilton
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
$193 nightly
The price is $226 total per night from Jul 1 to Jul 2
$226 total
Jul 1 - Jul 2
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and outdoor pool, and unwind with a drink at the poolside ...
8.6/10 Excellent! (1,000 reviews)
"The door on the toilet room is a really tight squeeze and actually stubbed my toe but other than that (oh and I thought there was a microwave but there was not) it was a good stay with a cool view of the river. Will take more advantage of the pool next time. We were there for a wedding this ..."

Reviewed on Jun 1, 2026

Opens in a new windowAmeristar Casino Resort and Spa
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4 Star Hotels Madison

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Madison 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Madison will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Madison, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Madison hotel reviews by fellow wanderers