Explore top 2025 4 Star Hotels in Jeffersonville - Clarksville

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Top Jeffersonville - Clarksville 4 Star hotels

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street, Louisville, KY
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $164 total per night from Nov 1 to Nov 2
$164 total
Nov 1 - Nov 2
Total with taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
8.8/10 Excellent! (3,648 reviews)
"Overall my stay was amazing. I expected a little more with it being more of an upscale hotel. The lobbies were upscale but the room was basic but nice and spacious. We were in the west tower and doors had to be basically slammed to shut. View from 21st floor was amazing. The shower and sink water ..."

Reviewed on Oct 5, 2025

Opens in a new windowGalt House Hotel Trademark Collection by Wyndham
Omni Louisville Hotel

Omni Louisville Hotel

4 out of 5
400 S. 2nd Street, Louisville, KY
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $234 total per night from Oct 20 to Oct 21
$234 total
Oct 20 - Oct 21
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,625 reviews)
"We enjoyed our stay. The staff at the front desk were very friendly and helpful. Our room was comfy, loved the shower. There were several choices for dinner within walking distance."

Reviewed on Sep 29, 2025

Opens in a new windowOmni Louisville Hotel
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

4 out of 5
501 South Fourth Street, Louisville, KY
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $163 total per night from Oct 13 to Oct 14
$163 total
Oct 13 - Oct 14
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and WiFi in public areas. Valet ...
8.8/10 Excellent! (1,047 reviews)
"Very clean"

Reviewed on Sep 30, 2025

Opens in a new windowEmbassy Suites Louisville Downtown
Derby City Gaming & Hotel -  A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

4 out of 5
4520 Poplar Level Rd, Louisville, KY
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $140 total per night from Oct 9 to Oct 10
$140 total
Oct 9 - Oct 10
Total with taxes and fees
This smoke-free hotel features 3 restaurants and 3 bars/lounges. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...
9.4/10 Exceptional! (1,486 reviews)
"Very clean. Beautiful 🌹 room Nice people Over all very happy with everything"

Reviewed on Oct 1, 2025

Opens in a new windowDerby City Gaming & Hotel - A Churchill Downs Property
Hyatt Regency Louisville

Hyatt Regency Louisville

4 out of 5
320 West Jefferson Street, Louisville, KY
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $187 total per night from Oct 9 to Oct 10
$187 total
Oct 9 - Oct 10
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.6/10 Excellent! (1,000 reviews)
"Within walking distance to many downtown sights. Comfortable rooms. The staff was great. They made us feel welcome."

Reviewed on Sep 30, 2025

Opens in a new windowHyatt Regency Louisville
The Brown Hotel

The Brown Hotel

4.5 out of 5
335 W Broadway, Louisville, KY
Fully refundableReserve now, pay when you stay
$168 nightly
The price is $198 total per night from Nov 1 to Nov 2
$198 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
9.2/10 Wonderful! (1,090 reviews)
"Pillows messed up my neck but overall nice room."

Reviewed on Sep 29, 2025

Opens in a new windowThe Brown Hotel
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 out of 5
700 W Main Street, Louisville, KY
$184 nightly
The price is $216 total per night from Oct 31 to Nov 1
$216 total
Oct 31 - Nov 1
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.2/10 Wonderful! (1,002 reviews)
"Price was too high compared to similar hotels."

Reviewed on Oct 3, 2025

Opens in a new window21c Museum Hotel Louisville
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

4 out of 5
730 E Market St, Louisville, KY
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $159 total per night from Oct 13 to Oct 14
$159 total
Oct 13 - Oct 14
Total with taxes and fees
This hotel features 2 restaurants and 3 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a snack bar/deli are also offered.
9/10 Wonderful! (971 reviews)
Eclectic, comfy stay
"Very clean, tidy room with an eclectic vibe. Room was very comfortable and spacious. Check in/check out was easy and front desk staff were kind and friendly. Hotel was located near multiple resturants and points of interest."

Reviewed on Sep 29, 2025

Opens in a new windowHotel Genevieve part of JdV by Hyatt
Marriott Louisville East

Marriott Louisville East

4 out of 5
1903 Embassy Square Blvd, Louisville, KY
$118 nightly
The price is $139 total per night from Oct 12 to Oct 13
$139 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9/10 Wonderful! (1,001 reviews)
"Easily accessible. I did not agree with having to pay to park in their parking lot but, over all, nice hotel and clean."

Reviewed on Sep 29, 2025

Opens in a new windowMarriott Louisville East
Louisville Marriott Downtown

Louisville Marriott Downtown

4 out of 5
280 West Jefferson Street, Louisville, KY
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $201 total per night from Oct 31 to Nov 1
$201 total
Oct 31 - Nov 1
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (1,000 reviews)
"Great Hotel. Great restaurant. Great bar."

Reviewed on Sep 16, 2025

Opens in a new windowLouisville Marriott Downtown
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4 Star Hotels Jeffersonville - Clarksville

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Jeffersonville - Clarksville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Jeffersonville - Clarksville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Jeffersonville - Clarksville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Jeffersonville - Clarksville hotel reviews by fellow wanderers

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