Explore top 2026 4 Star Hotels in Jeffersonville - Clarksville

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Top Jeffersonville - Clarksville 4 Star hotels

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $175 total per night from Mar 22 to Mar 23
$175 total
Mar 22 - Mar 23
Total with taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
9/10 Wonderful! (4,099 reviews)
It was great

Reviewed on Mar 6, 2026

Opens in a new windowGalt House Hotel Trademark Collection by Wyndham
Omni Louisville Hotel

Omni Louisville Hotel

4 out of 5
400 S. 2nd Street Louisville KY
$183 nightly
The price is $216 total per night from Mar 29 to Mar 30
$216 total
Mar 29 - Mar 30
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,788 reviews)
!

Reviewed on Mar 7, 2026

Opens in a new windowOmni Louisville Hotel
Derby City Gaming & Hotel -  A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

4 out of 5
4520 Poplar Level Rd Louisville KY
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $133 total per night from Mar 9 to Mar 10
$133 total
Mar 9 - Mar 10
Total with taxes and fees
This smoke-free hotel features 3 restaurants and 3 bars/lounges. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...
9.4/10 Exceptional! (1,859 reviews)
Working in the area, so this was a fun, clean hotel to hang out in. Clean room, helpful staff, cold A/C. Very nice for the price.

Reviewed on Mar 8, 2026

Opens in a new windowDerby City Gaming & Hotel - A Churchill Downs Property
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

4 out of 5
501 South Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $135 total per night from Mar 15 to Mar 16
$135 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and a roundtrip airport shuttle. ...
9/10 Wonderful! (1,160 reviews)
Tried to cancel due to a venue change. The manager basically refused to talk to us. I have had hundreds of hotel stays . 1st time a manager has ghosted us. I am so upset with this out come I may quit Expedia and never stay in a embassy suites again.

Reviewed on Mar 7, 2026

Opens in a new windowEmbassy Suites Louisville Downtown
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

4 out of 5
730 E Market St Louisville KY
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $159 total per night from Mar 15 to Mar 16
$159 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant and 2 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a snack bar/deli are also offered.
9.2/10 Wonderful! (1,052 reviews)
Great location. Clean. Friendly staff.

Reviewed on Mar 7, 2026

Opens in a new windowHotel Genevieve part of JdV by Hyatt
The Brown Hotel

The Brown Hotel

4.5 out of 5
335 W Broadway Louisville KY
Fully refundableReserve now, pay when you stay
$178 nightly
The price is $210 total per night from Mar 19 to Mar 20
$210 total
Mar 19 - Mar 20
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
9.4/10 Exceptional! (1,188 reviews)
Second time around for our anniversary. Room wasn’t as nice,but still comfortable. Restaurant bar and servers were great! I’m sure we’ll be back again.

Reviewed on Mar 2, 2026

Opens in a new windowThe Brown Hotel
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 out of 5
700 W Main Street Louisville KY
Fully refundableReserve now, pay when you stay
$183 nightly
The price is $216 total per night from Mar 15 to Mar 16
$216 total
Mar 15 - Mar 16
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.4/10 Exceptional! (1,008 reviews)
Lovely hotel. Would stay there again.

Reviewed on Mar 5, 2026

Opens in a new window21c Museum Hotel Louisville
Hyatt Regency Louisville

Hyatt Regency Louisville

4 out of 5
320 West Jefferson Street Louisville KY
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $151 total per night from Apr 5 to Apr 6
$151 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.8/10 Excellent! (1,004 reviews)
Nice property, friendly staff, great downtown location

Reviewed on Mar 7, 2026

Opens in a new windowHyatt Regency Louisville
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

4 out of 5
143 West Market St Louisville KY
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $169 total per night from Apr 3 to Apr 4
$169 total
Apr 3 - Apr 4
Total with taxes and fees
This smoke-free hotel's 2 restaurants, 3 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (80 reviews)
If you want to sleep don’t stay here. Insanely loud cars race down the street next to the hotel all night. Absolutely insane noise and then the way the room is lighted boggled my mind, all off on one switch it is the switch is on you have to shut them all off except the one under the bed attached ...

Reviewed on Mar 8, 2026

Opens in a new windowHotel Bourré Bonne Louisville, Curio Collection by Hilton
Louisville Marriott Downtown

Louisville Marriott Downtown

4 out of 5
280 West Jefferson Street Louisville KY
Fully refundableReserve now, pay when you stay
$168 nightly
The price is $197 total per night from Apr 5 to Apr 6
$197 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (1,002 reviews)
Great place and very clean and professional

Reviewed on Feb 28, 2026

Opens in a new windowLouisville Marriott Downtown
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4 Star Hotels Jeffersonville - Clarksville

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Jeffersonville - Clarksville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Jeffersonville - Clarksville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Jeffersonville - Clarksville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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