Explore top 2026 4 Star Hotels in Jeffersonville - Clarksville

Name: Hotel Distil, Autograph Collection
Price range: $237 total

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Top Jeffersonville - Clarksville 4 Star hotels

Galt House Hotel Trademark Collection by Wyndham

140 North Fourth Street Louisville KY

Fully refundableReserve now, pay when you stay

$136 nightly

$160 total

Nov 8 - Nov 9

Total with taxes and fees

A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

The Brown Hotel

335 W Broadway Louisville KY

Fully refundableReserve now, pay when you stay

$130 nightly

$153 total

Nov 25 - Nov 26

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...

Derby City Gaming & Hotel - A Churchill Downs Property (Adults Only)

4520 Poplar Level Rd Louisville KY

Fully refundableReserve now, pay when you stay

$89 nightly

$105 total

Nov 16 - Nov 17

Total with taxes and fees

This smoke-free hotel features 3 restaurants and 3 bars/lounges. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...

9.4/10 Exceptional! (2,615 reviews)

"Awesome front desk team that was so friendly. Made me feel welcome. Bed is elite when compared to most hotels."

Reviewed on Oct 30, 2026

Omni Louisville Hotel

400 S. 2nd Street Louisville KY

Fully refundableReserve now, pay when you stay

$203 nightly

$239 total

Nov 16 - Nov 17

Total with taxes and fees

A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

Louisville Marriott Downtown

280 West Jefferson Street Louisville KY

Fully refundableReserve now, pay when you stay

$168 nightly

$197 total

Nov 22 - Nov 23

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9/10 Wonderful! (1,002 reviews)

"The hotel is walking distance to 4th Street Live which has plenty of restaurants and bars. Staff was professional, valet service was worth it, hotel is well kept. The glaring negative is that no matter what floor you are on, you are subjected to Fast and Furious car driving, excessively loud music ..."

Reviewed on Oct 27, 2026

Hyatt Regency Louisville

320 West Jefferson Street Louisville KY

Fully refundableReserve now, pay when you stay

$126 nightly

$148 total

Nov 27 - Nov 28

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

8.8/10 Excellent! (1,000 reviews)

"There was no room available for my accommodation after I drove 6 hours and notifies the hotel of my arrival time. When I got to the registration desk I was notified that the hotel was full and I needed to stay at an hotel that was substandard to the Hyatt. I was then directed to a holiday inn that ..."

Reviewed on Oct 24, 2026

Embassy Suites Louisville Downtown

501 South Fourth Street Louisville KY

Fully refundableReserve now, pay when you stay

$130 nightly

$153 total

Nov 23 - Nov 24

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and a roundtrip airport shuttle. ...

The Grady

601 W Main St Louisville KY

Fully refundableReserve now, pay when you stay

$171 nightly

$201 total

Nov 29 - Nov 30

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a coffee shop, and a library are also offered.

21c Museum Hotel Louisville

700 W Main Street Louisville KY

Fully refundableReserve now, pay when you stay

$156 nightly

$184 total

Nov 23 - Nov 24

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

Hotel Distil, Autograph Collection

101 West Main Street Louisville KY

Fully refundableReserve now, pay when you stay

$202 nightly

$237 total

Nov 22 - Nov 23

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Jeffersonville - Clarksville

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Jeffersonville - Clarksville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Jeffersonville - Clarksville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Jeffersonville - Clarksville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.