Explore top 2026 4 Star Hotels in Jeffersonville - Clarksville

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Apr 27 - Apr 28
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Top Jeffersonville - Clarksville 4 Star hotels

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from May 23 to May 24
$143 total
May 23 - May 24
Total with taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
9/10 Wonderful! (4,205 reviews)
Really nice facilities but the rooms themselves could be cleaner. My initial room had pee stains all over the toilet upon entering and though they happily gave me a new room, the bathroom had a clothes tag in the new room. It just felt like they didn't clean the rooms properly. The facilities are ...

Reviewed on Apr 27, 2026

Opens in a new windowGalt House Hotel Trademark Collection by Wyndham
Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

4 out of 5
4520 Poplar Level Rd Louisville KY
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $133 total per night from May 18 to May 19
$133 total
May 18 - May 19
Total with taxes and fees
This smoke-free hotel features 3 restaurants and 3 bars/lounges. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...
9.4/10 Exceptional! (2,013 reviews)
Spacious room and bathroom, including the shower.

Reviewed on Apr 27, 2026

Opens in a new windowDerby City Gaming & Hotel - A Churchill Downs Property
Omni Louisville Hotel

Omni Louisville Hotel

4 out of 5
400 S. 2nd Street Louisville KY
Fully refundableReserve now, pay when you stay
$249 nightly
The price is $293 total per night from May 3 to May 4
$293 total
May 3 - May 4
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,858 reviews)
Great!

Reviewed on Apr 27, 2026

Opens in a new windowOmni Louisville Hotel
The Brown Hotel

The Brown Hotel

4.5 out of 5
335 W Broadway Louisville KY
Fully refundableReserve now, pay when you stay
$154 nightly
The price is $182 total per night from May 27 to May 28
$182 total
May 27 - May 28
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
9.4/10 Exceptional! (1,177 reviews)
Excellent all around

Reviewed on Apr 27, 2026

Opens in a new windowThe Brown Hotel
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

4 out of 5
501 South Fourth Street Louisville KY
$122 nightly
The price is $143 total per night from May 26 to May 27
$143 total
May 26 - May 27
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and a roundtrip airport shuttle. ...
9/10 Wonderful! (1,202 reviews)
Great place, secure and super clean. The rooms are Hugh and was made to feel like home

Reviewed on Apr 26, 2026

Opens in a new windowEmbassy Suites Louisville Downtown
Louisville Marriott Downtown

Louisville Marriott Downtown

4 out of 5
280 West Jefferson Street Louisville KY
$171 nightly
The price is $201 total per night from May 22 to May 23
$201 total
May 22 - May 23
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (1,003 reviews)
Perfect location

Reviewed on Apr 27, 2026

Opens in a new windowLouisville Marriott Downtown
Hyatt Regency Louisville

Hyatt Regency Louisville

4 out of 5
320 West Jefferson Street Louisville KY
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from Apr 29 to Apr 30
$149 total
Apr 29 - Apr 30
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.8/10 Excellent! (1,007 reviews)
Everything was nice

Reviewed on Apr 26, 2026

Opens in a new windowHyatt Regency Louisville
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

4 out of 5
730 E Market St Louisville KY
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $159 total per night from May 10 to May 11
$159 total
May 10 - May 11
Total with taxes and fees
This hotel features a restaurant and 2 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a snack bar/deli are also offered.
9.2/10 Wonderful! (1,081 reviews)
The rooftop bar was beautiful on the inside! The outside portion was just ok, was hoping for a bit nicer and better service. Overall, a fine enough experience though.

Reviewed on Apr 23, 2026

Opens in a new windowHotel Genevieve part of JdV by Hyatt
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 out of 5
700 W Main Street Louisville KY
Fully refundableReserve now, pay when you stay
$156 nightly
The price is $184 total per night from May 25 to May 26
$184 total
May 25 - May 26
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.4/10 Exceptional! (1,002 reviews)
Unique venue with some many amenities. Staff are super helpful and hospital. Will stay again when I’m in town.

Reviewed on Apr 23, 2026

Opens in a new window21c Museum Hotel Louisville
Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection

4 out of 5
101 West Main Street Louisville KY
Fully refundableReserve now, pay when you stay
$175 nightly
The price is $206 total per night from May 25 to May 26
$206 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...
9.6/10 Exceptional! (463 reviews)
Hotel was great. Staff amazing. We stayed in Louisville on a Sunday night and were surprised that most restaurants and bars were closed Sunday/Mondays.

Reviewed on Apr 22, 2026

Opens in a new windowHotel Distil, Autograph Collection
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Jeffersonville - Clarksville

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Jeffersonville - Clarksville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Jeffersonville - Clarksville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Jeffersonville - Clarksville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Jeffersonville - Clarksville hotel reviews by fellow wanderers

Radisson Hotel Louisville North

Radisson Hotel Louisville North

2 out of 5
Posted 5 hours ago
Travelocity Verified Review
"The room was outdated, smelled slightly and gave us an unclean feeling. The room was cleaned but it was very worn. When we booked our room, we booked double beds but somehow our booking was taken/ sold before our arrival. The one staff on duty gave us a King sized bed and a roll out bed in comparison to the double beds we requested. This is not comparable. The roll out bed was made of wires and little cushion. It had no covers so they gave us like 25 pillow cases and a mattress protector to use for covers. CRAZYY! I could barely walk the next morning after sleeping on the roll out couch. I paid for a bed and got FAR less than what I asked or paid for even though they tried to convince us that the King sized suite would be "an upgrade". NOT AT ALL"
A verified traveler stayed at Radisson Hotel Louisville North
Radisson Hotel Louisville North

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