Explore top 2025 4 Star Hotels in Gulf of Mexico

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Top Gulf of Mexico 4 Star hotels

The Westin New Orleans

The Westin New Orleans

4.5 out of 5
100 Rue Iberville, New Orleans, LA
Fully refundableReserve now, pay when you stay
$178 nightly
The price is $210 total per night from Oct 19 to Oct 20
$210 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (2,069 reviews)
"View of the river from my room was so nice, breakfast was very good, and bed was extremely comfy :) Would definitely visit again!"

Reviewed on Sep 21, 2025

Opens in a new windowThe Westin New Orleans
Bourbon Orleans Hotel

Bourbon Orleans Hotel

4 out of 5
717 Orleans St., New Orleans, LA
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $184 total per night from Sep 29 to Sep 30
$184 total
Sep 29 - Sep 30
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Relax with a drink at the bar/lounge and enjoy perks like free WiFi. Valet parking, a coffee shop, ...
9/10 Wonderful! (3,995 reviews)
Beautiful Boutique Hotel
"The Bourbon Orleans is a gorgeous boutique hotel steps from everything in the French Quarter. The lobby is a beautiful place to relax, the courtyard pool is tranquil and the rooms are clean and comfortable. Centrally located to everything in the FQ- it was easy to park the car and have a relaxing ..."

Reviewed on Sep 25, 2025

Opens in a new windowBourbon Orleans Hotel
Hilton Tampa Airport Westshore

Hilton Tampa Airport Westshore

4 out of 5
2225 N Lois Ave, Tampa, FL
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $129 total per night from Oct 5 to Oct 6
$129 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, express check-in, and free ...
8.4/10 Very Good! (1,036 reviews)
"Very nice hotel"

Reviewed on Sep 22, 2025

Opens in a new windowHilton Tampa Airport Westshore
IP Casino Resort Spa - Biloxi

IP Casino Resort Spa - Biloxi

4 out of 5
850 Bayview Ave, Biloxi, MS
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $104 total per night from Oct 2 to Oct 3
$104 total
Oct 2 - Oct 3
Total with taxes and fees
This resort features a casino, a full-service spa, and a nightclub. Enjoy a meal in one of the 7 restaurants and free perks like valet parking and WiFi in public ...
8.4/10 Very Good! (5,031 reviews)
Fabulous stay
"My Particular room was newly remodeled. It is beautiful .. no tub-nice marbled walk in shower. Nikia at check in very nice. This is our go-to hotel for most weekend getaways for great concerts. I really enjoyed The Chill Lounge after the concert. Live band -Fever Dream was there. Absolutely fabulous! ..."

Reviewed on Sep 21, 2025

Opens in a new windowIP Casino Resort Spa - Biloxi
Hyatt Regency New Orleans

Hyatt Regency New Orleans

4 out of 5
601 Loyola Avenue, New Orleans, LA
Fully refundableReserve now, pay when you stay
$170 nightly
The price is $201 total per night from Oct 3 to Oct 4
$201 total
Oct 3 - Oct 4
Total with taxes and fees
This smoke-free hotel features 3 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the 24-hour business center, free ...
9/10 Wonderful! (1,288 reviews)
Great stay
"Food was great! Staff were very friendly. Rooms were clean. Only thing was the A/C was a little slow to cool and bathroom was small. We will definitely be back!"

Reviewed on Sep 24, 2025

Opens in a new windowHyatt Regency New Orleans
Hilton St. Petersburg Bayfront

Hilton St. Petersburg Bayfront

4 out of 5
333 1st St S, St. Petersburg, FL
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $119 total per night from Oct 1 to Oct 2
$119 total
Oct 1 - Oct 2
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, express check-in, and valet parking. There's ...
7.6/10 Good! (1,020 reviews)
Love this hotel
"Amazing hotel walkable to restaurants and everything st Pete has to offer! Clean rooms and amenities. Very nice and will stay here again"

Reviewed on Sep 19, 2025

Opens in a new windowHilton St. Petersburg Bayfront
New Orleans Marriott

New Orleans Marriott

4 out of 5
555 Canal St, New Orleans, LA
Fully refundableReserve now, pay when you stay
$204 nightly
The price is $241 total per night from Oct 1 to Oct 2
$241 total
Oct 1 - Oct 2
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...
8.8/10 Excellent! (1,700 reviews)
"A hotel in downtown NOLA"

Reviewed on Sep 19, 2025

Opens in a new windowNew Orleans Marriott
Hard Rock Hotel & Casino Biloxi

Hard Rock Hotel & Casino Biloxi

4 out of 5
777 Beach Blvd., Biloxi, MS
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $96 total per night from Sep 30 to Oct 1
$96 total
Sep 30 - Oct 1
Total with taxes and fees
This hotel features a casino, a nightclub, and 5 restaurants. Enjoy the 4 outdoor pools and perks like free self parking and free WiFi. Make the most of the ...
8.2/10 Very Good! (3,220 reviews)
"Everything was great"

Reviewed on Sep 25, 2025

Opens in a new windowHard Rock Hotel & Casino Biloxi
Margaritaville Beach Resort South Padre Island

Margaritaville Beach Resort South Padre Island

4 out of 5
310 Padre Blvd, South Padre Island, TX
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $121 total per night from Oct 26 to Oct 27
$121 total
Oct 26 - Oct 27
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the express check-out, ...
8.6/10 Excellent! (1,657 reviews)
"Room was very clean and spacious for 2 of us. Room service staff was very friendly and helpful. Front desk staff was ok but need more pleasant personality. Overall resort is good and definitely return."

Reviewed on Sep 24, 2025

Opens in a new windowMargaritaville Beach Resort South Padre Island
The Island Resort at Fort Walton Beach

The Island Resort at Fort Walton Beach

4 out of 5
Miracle Strip Parkway Southeast, 1500, Fort Walton Beach, FL
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $150 total per night from Oct 26 to Oct 27
$150 total
Oct 26 - Oct 27
Total with taxes and fees
This resort features 2 restaurants, 2 outdoor pools, and a gym. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Bring the family and ...
8.2/10 Very Good! (2,881 reviews)
"The property was very nice and the staff was very very friendly. Everyone went above and beyond to make our stay wonderful. The only thing I would say I was unhappy with was the bathroom in our room. I don’t know if all the rooms are the same, but there was no countertop space whatsoever to really ..."

Reviewed on Sep 19, 2025

Opens in a new windowThe Island Resort at Fort Walton Beach
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4 Star Hotels Gulf of Mexico

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Gulf of Mexico 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Gulf of Mexico will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Gulf of Mexico, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Gulf of Mexico hotel reviews by fellow wanderers