Cheap Flights to Sikeston from $28
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How Much Does it Cost To Fly To Sikeston?
The cheapest prices found with in the last 7 days for return flights were $56 and $28 for one-way flights to Sikeston for the period specified. Prices and availability are subject to change. Additional terms apply
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$56 Roundtrip, found 1 hour ago
$56
Roundtrip
found 1 hour ago
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| ATL | St. Louis | July 19 to July 22 | $56 |
| DEN | St. Louis | June 2 to June 9 | $90 |
| DFW | St. Louis | July 7 to July 8 | $136 |
| DFW | Scott City | July 17 to July 23 | $178 |
| TPA | St. Louis | July 21 to July 28 | $190 |
| LGA | St. Louis | August 11 to August 12 | $200 |
| LGA | St. Louis | August 11 to August 12 | $200 |
| LAX | St. Louis | May 26 to June 3 | $220 |
| SEA | St. Louis | June 4 to June 9 | $285 |
| TPA | West Paducah | July 9 to July 12 | $294 |
| DFW | West Paducah | May 30 to June 2 | $489 |
| LAX | Scott City | May 20 to May 24 | $682 |
| FCO | St. Louis | May 20 to May 24 | $908 |
| DEN | Scott City | May 24 to May 26 | $1,072 |
| ATL | Scott City | July 19 to July 31 | $1,325 |
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| DEN | St. Louis | May 17 to May 24 | $286 |
| TPA | St. Louis | May 17 to May 23 | $287 |
| DFW | St. Louis | May 17 to May 23 | $320 |
| ATL | St. Louis | May 17 to May 18 | $324 |
| EWR | St. Louis | May 17 to May 19 | $378 |
| SEA | St. Louis | May 15 to May 19 | $416 |
| PHL | St. Louis | May 15 to May 17 | $419 |
| LGA | St. Louis | May 16 to May 18 | $436 |
| DFW | Scott City | May 15 to May 18 | $447 |
| LAX | St. Louis | May 16 to May 18 | $463 |
Sikeston Flight Information
Traveling to | Sikeston |
|---|---|
Lowest Price | $56 |
Number of Airlines Serving | |
Airlines Serving | Frontier Airlines |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Sikeston Accommodation Deals
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
$72 nightly
The price is $81 total per night from May 17 to May 18
$81 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,008 reviews)
People were allowed to party and laugh and rev their engines outside our room. When we complained to the front desk we were told that they are just relaxing. after a second call to the desk they finally went to their room where they played loud music. The desk showed no interest in helping us. All ...
Reviewed on May 10, 2026
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$64 nightly
The price is $73 total per night from May 17 to May 18
$73 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
$105 nightly
The price is $118 total per night from May 17 to May 18
$118 total
May 17 - May 18
Total with taxes and fees
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,006 reviews)
Room was very clean. Breakfast was good with several options. Would recommend staying here.
Reviewed on May 6, 2026
Save an average of 15% on thousands of hotels when you're signed in
Eagle Inn Charleston
2811 East Marshall Street Charleston MO
$69 nightly
The price is $77 total per night from May 11 to May 12
$77 total
May 11 - May 12
Total with taxes and fees
Stay at this motel in Charleston. Enjoy free WiFi, free parking, and a health club.
6.6/10 (106 reviews)
Great
Reviewed on Apr 14, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Luxury Hotels in Sikeston
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$64 nightly
The price is $73 total per night from May 17 to May 18
$73 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Cape Girardeau MO
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Riverfront Park and eDen Spa & Salon are located ...
10/10 Exceptional! (225 reviews)
Amazing place to stay at the Cape!
Reviewed on Apr 12, 2026
Quality Inn Cape Girardeau North
2011 North Kingshighway Cape Girardeau MO
$67 nightly
The price is $75 total per night from May 17 to May 18
$75 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7.2/10 Good! (739 reviews)
The place was not good at all. If it wasn't for it being so late at night when we arrived, I would have left and demanded a refund. Room was as if someone before me had just left 5 minutes prior to me going in. Not clean at all!!
Reviewed on May 6, 2026
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Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$111 nightly
The price is $128 total per night from May 15 to May 16
$128 total
May 15 - May 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,013 reviews)
Breakfast was good
Reviewed on May 9, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Sikeston
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$111 nightly
The price is $128 total per night from May 15 to May 16
$128 total
May 15 - May 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,013 reviews)
Breakfast was good
Reviewed on May 9, 2026
Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
$81 nightly
The price is $92 total per night from May 20 to May 21
$92 total
May 20 - May 21
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,004 reviews)
We had a one night stay. The staff was very friendly. Quiet. Slept comfortably. Breakfast was plentiful & enjoyable. The only issue we had was that our room keys kept messing up. Oh, the water could have been hotter. No biggies though. We would definitely stay again.
Reviewed on May 10, 2026
Drury Inn & Suites Cape Girardeau
3303 Campster Drive Cape Girardeau MO
$90 nightly
The price is $102 total per night from May 17 to May 18
$102 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (1,007 reviews)
Clean room all good
Reviewed on May 8, 2026
Save an average of 15% on thousands of hotels when you're signed in
Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd Jackson MO
$92 nightly
The price is $100 total per night from May 17 to May 18
$100 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
8.2/10 Very Good! (765 reviews)
Air Conditioning was noisy, the bathroom door did not close. The linens were dingy. The furniture was subpar, lots of damage on them scratches and dings. The carpet was stained and dirty, the bathroom had water damage around the tub and there were cracks in the ceiling drywall.
Reviewed on Apr 27, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best Sikeston Flight and Hotel Packages
Sikeston flight + hotel packages - economy flights
Price found within the past 48 hours. Click for updated prices.
Need a Car For After Your Flight?
Compact SUV
St Louis, Missouri, USA
$43
$112 total
found 3 days ago
Midsize SUV
St Louis, Missouri, USA
$45
$117 total
found 3 days ago
Special
Saint Ann, Missouri, USA
$47
$128 total
found 3 days ago
Standard SUV
St Louis, Missouri, USA
$48
$124 total
found 3 days ago
Lowest prices found within the past 3 days. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Plane Tickets To Sikeston
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