Cheap Flights to Sikeston from $29
Wander Wisely with exceptional service, 24/7 supportOpens in a new window
Feel at ease with free flight cancellations within 24 hours of booking
Change your flight without a fee on select flights
How Much Does it Cost To Fly To Sikeston?
The cheapest prices found with in the last 7 days for return flights were $58 and $29 for one-way flights to Sikeston for the period specified. Prices and availability are subject to change. Additional terms apply
MCO
Orlando Intl.
STL
Lambert-St. Louis Intl.
$58 Roundtrip, found 17 hours ago
$58
Roundtrip
found 17 hours ago
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| ATL | St. Louis | March 31 to April 7 | $59 |
| JFK | St. Louis | January 31 to February 7 | $128 |
| PHL | St. Louis | February 10 to February 18 | $128 |
| DFW | St. Louis | January 31 to February 7 | $128 |
| DFW | Scott City | February 2 to February 11 | $139 |
| LGA | St. Louis | January 24 to January 26 | $146 |
| LAX | St. Louis | January 28 to January 31 | $148 |
| SEA | St. Louis | February 11 to February 18 | $159 |
| DEN | Scott City | February 18 to February 23 | $338 |
| DEN | West Paducah | February 15 to February 18 | $397 |
| SEA | Scott City | January 29 to February 2 | $416 |
| EWR | West Paducah | January 16 to January 17 | $517 |
| PHL | Scott City | January 11 to January 18 | $540 |
| FCO | St. Louis | March 13 to March 21 | $749 |
| TPA | Scott City | March 13 to March 22 | $6,081 |
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| DFW | St. Louis | January 10 to January 17 | $191 |
| PHL | St. Louis | January 10 to January 12 | $204 |
| DFW | Scott City | January 11 to January 18 | $209 |
| ATL | St. Louis | January 10 to January 12 | $217 |
| DEN | St. Louis | January 10 to January 11 | $229 |
| JFK | St. Louis | January 11 to January 14 | $236 |
| TPA | St. Louis | January 9 to January 14 | $239 |
| SEA | St. Louis | January 11 to January 15 | $263 |
| LGA | St. Louis | January 9 to January 11 | $305 |
| LAX | St. Louis | January 11 to January 15 | $308 |
| PHL | Scott City | January 11 to January 18 | $540 |
Sikeston Flight Information
Traveling to | Sikeston |
|---|---|
Lowest Price | $58 |
Number of Airlines Serving | |
Airlines Serving | Frontier Airlines |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Sikeston Accommodation Deals
Pear Tree Inn Sikeston
2602 E Malone Avenue Sikeston MO
$75 nightly
The price is $86 total per night from Jan 8 to Jan 9
$86 total
Jan 8 - Jan 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,006 reviews)
Everything was good. Clean, fast internet. Good food. Friendly staff.
Reviewed on Jan 3, 2026
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
$70 nightly
The price is $79 total per night from Jan 8 to Jan 9
$79 total
Jan 8 - Jan 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,002 reviews)
The rooms super immaculate super clean extremely comfortable the staff was very kind courteous and very competent in every way
Reviewed on Jan 2, 2026
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$63 nightly
The price is $72 total per night from Jan 6 to Jan 7
$72 total
Jan 6 - Jan 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,001 reviews)
Staff was very nice. Room layout with two separate rooms was appreciated, especially at this price point. Good bed and bedding. Not super high end or careful about the rehab, and the breakfast was a carb fest, but overall we still felt it was a very good value
Reviewed on Dec 26, 2025
Save an average of 15% on thousands of hotels when you're signed in
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
$91 nightly
The price is $103 total per night from Jan 11 to Jan 12
$103 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,001 reviews)
Nice!
Reviewed on Jan 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Luxury Hotels in Sikeston
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$63 nightly
The price is $72 total per night from Jan 6 to Jan 7
$72 total
Jan 6 - Jan 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,001 reviews)
Staff was very nice. Room layout with two separate rooms was appreciated, especially at this price point. Good bed and bedding. Not super high end or careful about the rehab, and the breakfast was a carb fest, but overall we still felt it was a very good value
Reviewed on Dec 26, 2025
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Cape Girardeau MO
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, a water park, and laundry facilities. Popular attractions Riverfront Park and eDen Spa & Salon are ...
9.8/10 Exceptional! (172 reviews)
Great location, quality bedding and pillows, and other comfortable amenities for a short getaway in historic downtown Cape Girardeau. Excellent value!
Reviewed on Dec 15, 2025
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St Cape Girardeau MO
$70 nightly
The price is $79 total per night from Jan 8 to Jan 9
$79 total
Jan 8 - Jan 9
Total with taxes and fees
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (1,003 reviews)
Everything was wonderful. Staff (especially Debbie) was the best. This is a nice quiet comfortable pplace to stay
Reviewed on Dec 26, 2025
Save an average of 15% on thousands of hotels when you're signed in
Quality Inn
2011 North Kingshighway Cape Girardeau MO
$59 nightly
The price is $67 total per night from Jan 22 to Jan 23
$67 total
Jan 22 - Jan 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7/10 Good! (689 reviews)
The room was clean and nice. The breakfast was really good.
Reviewed on Dec 28, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Sikeston
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$90 nightly
The price is $103 total per night from Jan 8 to Jan 9
$103 total
Jan 8 - Jan 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,003 reviews)
Everything was great
Reviewed on Dec 29, 2025
Pear Tree Inn Sikeston
2602 E Malone Avenue Sikeston MO
$75 nightly
The price is $86 total per night from Jan 8 to Jan 9
$86 total
Jan 8 - Jan 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,006 reviews)
Everything was good. Clean, fast internet. Good food. Friendly staff.
Reviewed on Jan 3, 2026
Best Western Plus Sikeston
120 S Interstate Drive Sikeston MO
$77 nightly
The price is $88 total per night from Jan 8 to Jan 9
$88 total
Jan 8 - Jan 9
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,003 reviews)
Nice and affordable option! Quiet place with clean facility throughout. Great people and good service.
Reviewed on Dec 29, 2025
Save an average of 15% on thousands of hotels when you're signed in
Drury Inn & Suites Cape Girardeau
3303 Campster Drive Cape Girardeau MO
$90 nightly
The price is $102 total per night from Jan 8 to Jan 9
$102 total
Jan 8 - Jan 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (1,006 reviews)
Clean one night stay
Reviewed on Jan 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best Sikeston Flight and Hotel Packages
Sikeston flight + hotel packages - economy flights
Price found within the past 48 hours. Click for updated prices.
Don't see what you're looking for?
See all available trips from Newark Liberty Intl. Airport to Sikeston
View all tripsNeed a Car For After Your Flight?
Economy Special
St Louis, Missouri, USA
$33
$85 total
found 2 days ago
Compact
St Louis, Missouri, USA
$36
$93 total
found 2 days ago
Midsize
St Louis, Missouri, USA
$38
$98 total
found 1 day ago
Special
Saint Ann, Missouri, USA
$38
$104 total
found 5 hours ago
Lowest prices found within the past 2 days. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Plane Tickets To Sikeston
Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Sikeston. Browse through our inventory to explore a wide range of cheap flights to Sikeston to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Sikeston as you anxiously await to exit the plane and explore what Sikeston has to offer. Considering all the amazing local food and culture in Sikeston, we won't hold this against you.
When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Sikeston to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Sikeston without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Sikeston with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Sikeston today!
Explore More Ways to Travel with Travelocity
- Hotels near Sikeston Depot Museum
- Hotels near New Madrid Historical Museum
- Hotels near Dexter Welcome Center Depot and Museum
- Hotels near Stoddard County Civil War Memorial Cemetery
- Lodges in Benton
- Hotels near Hunter-Dawson State Historic Site
- Bertrand Hotels
- Blodgett Hotels
- Cabins in Dexter
- Cheap Hotels in Dexter
- Historic Hotels in Dexter
- Hotels with Pools in Dexter
- Hotels with Free Breakfast in Dexter
- Dexter Hotels
- Motels in Dexter
- Vacation Homes in Dexter
- Chaffee Hotels
- Hotels near Central Park
- Cabins in Scott City
- Parma Hotels
- Cabins in Bloomfield
- Bloomfield Hotels
- Motels in Bloomfield
- Catron Hotels
- East Prairie Hotels
- Motels in East Prairie
- Vacation Homes in East Prairie
- Hotels with smoking rooms in Charleston
- Pet Friendly Hotels in Charleston
- Spa Resorts & in Charleston
- Charleston Hotels
- Motels in Charleston
- New Madrid Hotels
- Houseboats in New Madrid
- Motels in New Madrid
- Vacation Homes in New Madrid
- Hotels near River Ridge Winery
- Hotels near Sikeston Memorial Municipal
- Hotels near Big Oak Tree State Park
- 3 Star Hotels in Oran
- Apartments in Oran
- Oran Hotels
- Motels in Oran
- Hotels near Front Street Studio & Art Gallery
- Flights to Flat River
- Flights to Southeast Missouri
- Flights to Poplar Bluff
- Flights to Eminence
- Flights to Alton
- Flights to Cape Girardeau
- Flights to Jackson
- Flights from Cape Girardeau Municipal
- United Chicago (ORD) to Cape Girardeau (CGI) flights
- Flights from Atlanta (ATL) to Cape Girardeau (CGI)
- Flights from Nashville (BNA) to Cape Girardeau (CGI)
- Flights from Columbia (COU) to Cape Girardeau (CGI)
- Flights from Dallas (DFW) to Cape Girardeau (CGI)
- Flights from Kansas City (MCI) to Cape Girardeau (CGI)
- Flights from Chicago (ORD) to Cape Girardeau (CGI)
- Flights from St. Louis (STL) to Cape Girardeau (CGI)
- Flights to Farmington
- Flights to Bertrand
- Flights to Dexter
- Flights from Chicago to Dexter
- Flights from Houston to Dexter
- Flights from Miami to Dexter
- Flights from Washington to Dexter
- Flights to Malden
- Flights to East Prairie
- Flights from Boston to Charleston
- Flights to Ste Genevieve
- Flights to Doniphan
- Flights to New Madrid
- Flights to Fredericktown
- Flights to Ellington
- Flights to Kennett
- Flights from Sikeston Memorial Municipal
- Flights to Caruthersville
- Flights to Annapolis
- Flights to Hayti
- Flights to Steele
- Flights to Festus
- Flights to Couch
- Flights to Perryville
- Flights to Potosi
- Avis Rental Cars in Cape Girardeau Municipal
- Budget Rental Cars in Cape Girardeau Municipal
- Enterprise Rental Cars in Cape Girardeau Municipal
- Thrifty Car Rental Rental Cars in Cape Girardeau Municipal
- Car rental Dexter
- Luxury Car Rentals in Dexter
- Premium Car Rentals in Dexter
- Van Car Rentals in Dexter
- Car rental Catron
- Car rental East Prairie
- Car rental Charleston
- Fullsize Car Rentals in Charleston
- Premium Car Rentals in New Madrid