Book Lodges in Southeast Missouri, MO

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Featured Southeast Missouri Lodges

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southeast Missouri Mountain Accommodation

Southeast Missouri Ski Accommodation

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

4800 U.S. Highway 67, De Soto, MO
9.4/10 Exceptional! (143 reviews)

Top Trending Hotels in Southeast Missouri

Book a Lodge in Southeast Missouri

If what you’re missing most is the peacefulness of being out in nature, you might want to think about planning an easy staycation nearby. Over the years you’ve spent time fishing at stunning blue lakes, waking up at dawn to watch the sun rise in dense forests, and even hiking to the top of mountains just to get an incredible view. Booking a lodge accommodation nearby can be a great way to escape reality for a little bit, while keeping to yourself. On your next trip out of town, enjoy a little staycation in nature by booking your stay at a lodge resort in Southeast Missouri.


Southeast Missouri is known for its natural wonders, and lodge bookings can be one of the best ways to get the perfect blend of nature and relaxation you’ve been looking for. Whether you plan to spend your entire trip hiking, working, or simply meditating outdoors, you’ll be happy to return to one of our lodge rentals at the end of the day. Your room will be ultra-comfortable, but we’re fairly certain you won’t spend too much time inside. Reach into your mini-fridge and grab the iced coffee you stashed for your morning hike—there’s nothing like caffeinating while taking in sweeping views of towering trees and spotting birds.


Choose from a variety of lodging offered in Southeast Missouri, from rustic rentals to luxury lodges perfect for impressing your significant other. Spa tubs and kitchenettes? Why yes, we’ll join you for a romantic breakfast.


Searching for some peace and quiet? Whatever brings you to Southeast Missouri, there’s a lodge that’ll make you feel right at home. Trust Travelocity to help you find the place that makes your wandering heart sing.

Southeast Missouri Lodges essential information

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Wilderness Lodge, YMCA Trout Lodge, Secluded 5-Bedroom Lodge with Private Lake – Perfect for Large Groups!, Spring Lake Ranch has a Private, Rustic Lodge perfect for family/group retreats!, Alpaca Farm Stay, Sunnen Lodge YMCA Lofted Room | Meals Included, The Lodge @ Stormy Mountain Ranch Close drive to Emience and surrounding springs, SOLAR ECLIPSE! Lodge on10ac open field. 4 bed, 1 bath. Family/Pet friendly, Lake View | 3 Meals Per Day Included