Book Hotels in Scott City, MO
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Scott City hotels

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Aug 24 to Aug 25
$102 total
Aug 24 - Aug 25
Total includes taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Enjoy my stay here. Very nice room and the breakfast was nice"
Reviewed on Aug 18, 2025

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street, Cape Girardeau, MO
Fully refundable
$103 nightly
The price is $116 total per night from Sep 1 to Sep 2
$116 total
Sep 1 - Sep 2
Total includes taxes and fees
A full-service spa and an indoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public ...
"It was great had a wonderful time with my in-laws."
Reviewed on Aug 17, 2025

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $103 total per night from Aug 24 to Aug 25
$103 total
Aug 24 - Aug 25
Total includes taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Great location"
Reviewed on Aug 14, 2025

The Riverview
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $132 total per night from Aug 20 to Aug 21
$132 total
Aug 20 - Aug 21
Total includes taxes and fees
This hotel features a casino and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference space. ...
"Nice place to stay! everything was fun and clean."
Reviewed on Aug 14, 2025

Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Aug 20 to Aug 21
$79 total
Aug 20 - Aug 21
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Ok hotel. Good for a single night stop over. Next to outback."
Reviewed on Aug 17, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Aug 21 to Aug 22
$79 total
Aug 21 - Aug 22
Total includes taxes and fees
Free WiFi in public areas and express check-out are available at this hotel. Staff at the 24-hour front desk can provide around-the-clock assistance.
The go to!
"Always friendly and clean. My go to in the Cape!"
Reviewed on Aug 13, 2025

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $86 total per night from Sep 1 to Sep 2
$86 total
Sep 1 - Sep 2
Total includes taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Clean and friendly staff."
Reviewed on Aug 16, 2025

Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $92 total per night from Aug 24 to Aug 25
$92 total
Aug 24 - Aug 25
Total includes taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...
I would stay again
"We did not use the internet or have the breakfast so I have no feedback on those. The room seemed clean and so did the bathroom. The bathroom did have some paint peeling in one spot. The worst thing I can say is the mattress was firmer than I like. The hotel was quiet, easily accessible, equipped ..."
Reviewed on Aug 10, 2025

Building at Cape Girardeau Regional Airport
Scott City
$571 nightly
The price is $611 total per night from Aug 20 to Aug 21
$611 total
Aug 20 - Aug 21
Total includes taxes and fees
Stay at this vacation home in Scott City. Enjoy air conditioning. Popular attractions Fort D Historic Site and Riverfront Bridge Park are located nearby.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Scott City hotel reviews by fellow wanderers

Drury Plaza Hotel Cape Girardeau Conference Center
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Enjoy my stay here. Very nice room and the breakfast was nice"
A verified traveler stayed at Drury Plaza Hotel Cape Girardeau Conference Center
Explore More Ways to Travel with Travelocity
Explore More Ways to Travel with Travelocity
Accommodation Types
An Attraction
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Ohio River
- Hotels near Southeast Missouri State University
- Hotels near Isle Casino Cape Girardeau
- Hotels near Riverfront Bridge Park
- Hotels near Trail of Tears State Park
- Hotels near Cape Splash Family Aquatic Center
- Hotels near Cape Girardeau Conservation Nature Center
- Hotels near Sikeston Depot Museum
- Hotels near Central Park
- Hotels near Mound City National Cemetery
- Hotels near Lazy L Safari Park
- Hotels near Front Street Studio & Art Gallery
- Cape Girardeau Hotels
- Sikeston Hotels
- Ozarks Hotels
- Southern Illinois Hotels
- Jackson Hotels
- Cobden Hotels
- Anna Hotels
- Cairo Hotels
- Charleston Hotels
- Alto Pass Hotels
- Southeast Missouri Hotels
- Miner Hotels
- Jonesboro Hotels
- Central United States Hotels
- The South Hotels
- Dongola Hotels
- Benton Hotels
- Ullin Hotels
- Oran Hotels
- Tamms Hotels
- Advance Hotels
- Great River Road Hotels
- Mounds Hotels
- East Prairie Hotels
- Barlow Hotels
- Chaffee Hotels
- Fruitland Hotels
- Mound City Hotels
- Bertrand Hotels
- East Cape Girardeau Hotels
- Thebes Hotels
- Villa Ridge Hotels
- Dutchtown Hotels
- Southwest Illinois Hotels
- Gordonville Hotels
Most popular
Hotels
- Cheap Hotels in Joplin
- Cheap Hotels in Jefferson City
- Branson Pet Friendly Hotels
- Cheap Hotels in Fulton
- Cheap Hotels in Lebanon
- Cheap Hotels in Springfield
- Branson Kid Friendly Hotels
- Cheap Hotels in St. Joseph
- Cheap Hotels in Clinton
- Cheap Hotels in Camdenton
- Branson Hotels with an Indoor Pool
- Branson Hotels with Hot Tubs
- Cheap Hotels in Lake Ozark
- Cheap Hotels in Poplar Bluff
- Cheap Hotels in Farmington
- Cheap Hotels in Rolla
- Cheap Hotels in Washington
- Cheap Hotels in Columbia
- Cheap Hotels in Sedalia
- Cheap Hotels in Cape Girardeau
- Cheap Hotels in Branson
- Cheap Hotels in Osage Beach
- Cheap Hotels in Hannibal
Activities
Packages