Book a hotel near Santee National Wildlife Refuge, Summerton
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Top hotels close to Santee National Wildlife Refuge

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly.
Summerton SC
Free Cancellation
2.27 mi from Santee National Wildlife Refuge
$133 nightly
The price is $148 total per night
$148 total
Nov 16 - Nov 17
Total with taxes and fees
Stay at this cabin in Summerton. Enjoy patios, an in-room coffeemaker, and air conditioning. Popular attractions Santee Indian Mound and Fort Watson Site and Santee National Wildlife Refuge are located nearby.
Kitchen
Pet friendly

Relax and unwind near Lake Marion - 2-bedroom 1.5 bath cabin getaway.
Summerton SC
2.78 mi from Santee National Wildlife Refuge
$243 nightly
The price is $270 total per night
$270 total
Nov 17 - Nov 18
Total with taxes and fees
This cabin includes a garden and laundry facilities.
Kitchen
Washer

Lakefront Retreat on Lake Marion – Perfect for Fishing & Relaxation
Santee SC
3.34 mi from Santee National Wildlife Refuge
This condo featured laundry facilities and barbecue grills.
Kitchen
Washer

Quality Inn & Suites Santee I-95
8929 Old Number Six Highway Santee SC
Free Cancellation
4.26 mi from Santee National Wildlife Refuge
$59 nightly
The price is $65 total per night
$65 total
Dec 3 - Dec 4
Total with taxes and fees
This hotel features 7 restaurants and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Relax with a drink at the bar/lounge and enjoy free perks like full breakfast and free self parking.
Pool
Breakfast included

Hampton Inn Santee-I-95
9060 Old Number Six Hwy Santee SC
Free Cancellation
Reserve now, pay when you stay
4.36 mi from Santee National Wildlife Refuge
$124 nightly
The price is $138 total per night
$138 total
Dec 13 - Dec 14
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. A 24-hour business center, a terrace, and laundry facilities are also on offer.
Pool
Breakfast included

Best Western Plus Santee Inn
I 95 Exit 98 Santee SC
Free Cancellation
Reserve now, pay when you stay
4.36 mi from Santee National Wildlife Refuge
$119 nightly
The price is $132 total per night
$132 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.
Pool
Breakfast included

Fairfield Inn & Suites by Marriott Santee
9074 Old Number Six Hwy Santee SC
Free Cancellation
Reserve now, pay when you stay
4.36 mi from Santee National Wildlife Refuge
$130 nightly
The price is $144 total per night
$144 total
Nov 19 - Nov 20
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business center, a snack bar/deli, and a picnic area are also on offer.
Pool
Breakfast included

Travelodge by Wyndham Santee
9117 Old Number Six Hwy Santee SC
Free Cancellation
Reserve now, pay when you stay
4.38 mi from Santee National Wildlife Refuge
$65 nightly
The price is $72 total per night
$72 total
Nov 15 - Nov 16
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A safe deposit box is also provided.
Breakfast included
Pet friendly

Holiday Inn Santee by IHG
139 Bradford Blvd Santee SC
Free Cancellation
4.45 mi from Santee National Wildlife Refuge
$121 nightly
The price is $134 total per night
$134 total
Dec 13 - Dec 14
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the gym and perks like free self parking.
Pool
Pet friendly

Tru By Hilton Santee
263 Britain St. and 273 Britain St. Santee SC
Free Cancellation
Reserve now, pay when you stay
4.46 mi from Santee National Wildlife Refuge
$105 nightly
The price is $116 total per night
$116 total
Nov 29 - Nov 30
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide around-the-clock assistance.
Pool
Breakfast included

Baymont by Wyndham Santee
249 Britain Street Santee SC
Free Cancellation
Reserve now, pay when you stay
4.48 mi from Santee National Wildlife Refuge
$80 nightly
The price is $89 total per night
$89 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the express check-in and free internet in public areas. There's express check-out and multilingual staff can provide around-the-clock assistance.
Breakfast included
Pet friendly

Comfort Inn & Suites Santee
221 Britain St Santee SC
Free Cancellation
4.49 mi from Santee National Wildlife Refuge
$108 nightly
The price is $120 total per night
$120 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business center, a lobby fireplace, and laundry facilities are also on offer.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in Santee National Wildlife Refuge
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Santee National Wildlife Refuge hotels essential information
Accommodation | 433 hotels |
|---|---|
Lowest Price | $65 |
Highest Price | $270 |
Popular hotels | Tru By Hilton Santee, Baymont by Wyndham Santee, Fairfield Inn & Suites by Marriott Santee, Lakefront tiny cabin amazing view on Lake Marion! Pet friendly., Best Western Plus Santee Inn, Hampton Inn Santee-I-95, Comfort Inn & Suites Santee, Relax and unwind near Lake Marion - 2-bedroom 1.5 bath cabin getaway., Quality Inn & Suites Santee I-95, Holiday Inn Santee by IHG, Lakefront Retreat on Lake Marion – Perfect for Fishing & Relaxation, Travelodge by Wyndham Santee |
Recent Santee National Wildlife Refuge hotel reviews by fellow wanderers

Fairfield Inn & Suites by Marriott Santee
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"X"
A verified traveler stayed at Fairfield Inn & Suites by Marriott Santee
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