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Top hotels in Sanctuary

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
BED WERE VERY COMFOTABLE AND EXCELLENT SHOWER BEST EVER.
Reviewed on Mar 12, 2026

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Room smelled really bad
Reviewed on Mar 12, 2026

Sanibel Island Beach Resort
This is a lovely place. You step out onto the beach from the tiki bar and pool. Staff was very helpful. There’s a restaurant on site and was very good. The only thing I would recommend is if you can stay on the 2nd floor, there isn’t much in the way of sound proofing between the floors. You could ...
Reviewed on Mar 9, 2026

DiamondHead Beach Resort
Great place very nice. Music was too loud
Reviewed on Mar 12, 2026

Margaritaville Beach Resort Fort Myers
Clean room
Reviewed on Mar 11, 2026

Lani Kai Beachfront Resort
Great view from our balcony. No hairdryer. No iron in the roomn no full size ironing board. Room wasn't ready for 3:00 check in. Room was clean and neat. Restaurants were good. Only gave 4 star because there's always room for improvement. I would recommend.
Reviewed on Mar 12, 2026

The Westin Cape Coral Resort At Marina Village
Loved having 3 pools to choose from
Reviewed on Mar 9, 2026

Hilton Garden Inn Ft Myers
Clean room and nice staff. Didn't spend much time at the property.
Reviewed on Mar 12, 2026

Marriott Sanibel Harbour Resort & Spa
Pool was very enjoyable. Room was clean and spacious. We enjoyed the balcony. Great location to travel over bridge to Sanibel.
Reviewed on Mar 12, 2026
Sanctuary Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Sanctuary area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Sanctuary to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Sanctuary are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Sanctuary hotel reviews by fellow wanderers

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
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