Find a Hotel in Fort Myers River District

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top hotels in Fort Myers River District

Luminary Hotel & Co., Autograph Collection

Luminary Hotel & Co., Autograph Collection

4 out of 5
2200 Edwards Drive Fort Myers FL
Fully refundableReserve now, pay when you stay
$195 nightly
The price is $217 total per night from Nov 1 to Nov 2
$217 total
Nov 1 - Nov 2
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
"Great hotel! Wonderful staff"

Reviewed on Oct 21, 2026

Opens in a new windowLuminary Hotel & Co., Autograph Collection
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$210 nightly
The price is $234 total per night from Oct 26 to Oct 27
$234 total
Oct 26 - Oct 27
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
"Everything was good. The Island/Beach is struggling aince Hurricane Ian, so Margaritaville is about it. They need to clean their dirty and broken pool lounge chairs. $35 for overnight parking (no other option). 20% mandatory tip on all food and beverage purchases. Food and Drinks are $14-$19."

Reviewed on Oct 24, 2026

Opens in a new windowMargaritaville Beach Resort Fort Myers
The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

3 out of 5
1051 5th St Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $164 total per night from Oct 27 to Oct 28
$164 total
Oct 27 - Oct 28
Total with taxes and fees
This hotel features 2 outdoor pools, a restaurant, and a bar/lounge. Relax with a drink at the poolside bar and enjoy perks like free self parking and free WiFi. ...
"The staff was awesome. The front desk staff helped us through our many requests and changes for our stay, with a smile and a laugh. The room was way larger (and cleaner) than expected. The A/C was ice cold all weekend. The full sized fridge was an unexpected plus. We would recommend the Lighthouse ..."

Reviewed on Oct 24, 2026

Opens in a new windowThe Lighthouse Resort Inn & Suites
Hampton Inn Fort Myers Downtown

Hampton Inn Fort Myers Downtown

3 out of 5
2151 Johnson Street Fort Myers FL
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $126 total per night from Nov 22 to Nov 23
$126 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Opens in a new windowHampton Inn Fort Myers Downtown
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
$239 nightly
The price is $266 total per night from Nov 8 to Nov 9
$266 total
Nov 8 - Nov 9
Total with taxes and fees
A full-service spa, 4 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy the 5 outdoor tennis courts and indoor pool, and unwind ...
Opens in a new windowMarriott Sanibel Harbour Resort & Spa
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2.5 out of 5
1538 Cape Coral Pkwy E Cape Coral FL
Fully refundable
$101 nightly
The price is $113 total per night from Nov 1 to Nov 2
$113 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Opens in a new windowHoliday Inn Express Cape Coral-Fort Myers Area by IHG
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$165 nightly
The price is $184 total per night from Nov 3 to Nov 4
$184 total
Nov 3 - Nov 4
Total with taxes and fees
This smoke-free hotel features 3 restaurants, 3 beach bars, and 6 bars/lounges. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Enjoy ...
Opens in a new windowLani Kai Beachfront Resort
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
Fully refundableReserve now, pay when you stay
$204 nightly
The price is $227 total per night from Oct 26 to Oct 27
$227 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink ...
Opens in a new windowSanibel Island Beach Resort
Hyatt Vacation Club at Coconut Cove, Bonita Springs

Hyatt Vacation Club at Coconut Cove, Bonita Springs

4 out of 5
11800 Coconut Cove Drive Bonita Springs FL
$170 nightly
The price is $190 total per night from Oct 28 to Oct 29
$190 total
Oct 28 - Oct 29
Total with taxes and fees
3 outdoor pools, a lazy river, and a gym are all featured at this smoke-free hotel. There's fun for all ages with a children's pool and an arcade/game room, ...
Opens in a new windowHyatt Vacation Club at Coconut Cove, Bonita Springs
Don't see what you're looking for?
See all available properties in Fort Myers River District
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fort Myers River District Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Fort Myers River District area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Fort Myers River District to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Fort Myers River District are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Fort Myers River District hotel reviews by fellow wanderers

The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

5 out of 5
Posted 12 hours ago
Travelocity Verified Review
"The staff was awesome. The front desk staff helped us through our many requests and changes for our stay, with a smile and a laugh. The room was way larger (and cleaner) than expected. The A/C was ice cold all weekend. The full sized fridge was an unexpected plus. We would recommend the Lighthouse Resort to anyone and everyone that asks us. (We are full time residents in Lee County FL, BTW) This stay would have been perfect...if only the elevator had been repaired and we didn't have to carry our bags up two flights of stairs to the third floor. We'll be back!"
A verified traveler stayed at The Lighthouse Resort Inn & Suites
The Lighthouse Resort Inn & Suites

Explore More Ways to Travel with Travelocity