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Best Luxury Hotels in St. Louis

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$162 nightly
The price is $189 total per night from May 17 to May 18
$189 total
May 17 - May 18
Total with taxes and fees
2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...
9.6/10 Exceptional! (3,421 reviews)
Thank you for making it a great weekend getaway to St Louis!!

Reviewed on May 11, 2026

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO
Fully refundableReserve now, pay when you stay
$335 nightly
The price is $392 total per night from May 12 to May 13
$392 total
May 12 - May 13
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...
9.4/10 Exceptional! (1,001 reviews)
Food was excellent! Room was clean and wonderful!

Reviewed on Apr 22, 2026

Opens in a new windowFour Seasons Hotel St Louis
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO
Fully refundableReserve now, pay when you stay
$499 nightly
The price is $583 total per night from May 24 to May 25
$583 total
May 24 - May 25
Total with taxes and fees
This smoke-free hotel's 2 restaurants, 3 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
9.2/10 Wonderful! (567 reviews)
No swimming pool.....whole experience didn't seem top level

Reviewed on May 10, 2026

Opens in a new windowThe Ritz-Carlton, St. Louis
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$180 nightly
The price is $212 total per night from May 25 to May 26
$212 total
May 25 - May 26
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
9/10 Wonderful! (1,018 reviews)
The staff we encountered during our stay were delightful. It was a very pleasant experience.

Reviewed on May 11, 2026

Opens in a new window The Royal Sonesta Chase Park Plaza St. Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $116 total per night from May 31 to Jun 1
$116 total
May 31 - Jun 1
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
8.8/10 Excellent! (3,210 reviews)
The hotel is beautiful and a safe place to stay but in my 3 week stay, my room was cleaned twice (even after requesting more). I asked to have the parking fee removed for the 1 1/2 weeks that I was there since the parking garage gates were open the whole time and everyone in the city could park for ...

Reviewed on May 11, 2026

Opens in a new windowClayton Plaza Hotel & Extended Stay
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $126 total per night from May 27 to May 28
$126 total
May 27 - May 28
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.8/10 Excellent! (1,267 reviews)
COFFEE: Hotel does not have Decaf coffee. FIRE: In-room Fire Alarm BLASTED out "THIS IS NOT A DRILL. NOT A FALSE ALARM. A FIRE HAS BEEN REPORTED IN THE BUILDING. PLEASE EXIT THE BUILDING ASAP USING THE NEAREST STAIRS TO YOU”. We frantically gather essentials, in our pajamas, key belongings running ...

Reviewed on May 11, 2026

Opens in a new windowMagnolia Hotel St. Louis, a Tribute Portfolio Hotel
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
$193 nightly
The price is $226 total per night from May 12 to May 13
$226 total
May 12 - May 13
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and outdoor pool, and unwind with a drink at the poolside ...
8.6/10 Excellent! (1,011 reviews)
Never ever will go back. Go somewhere else. This was horrible. Went for a mother’s day weekend and the experience was truly awful.

Reviewed on May 10, 2026

Opens in a new windowAmeristar Casino Resort and Spa
The Westin St. Louis

The Westin St. Louis

811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $169 total per night from May 24 to May 25
$169 total
May 24 - May 25
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.6/10 Excellent! (1,010 reviews)
The room we stayed in needed a lot of maintenance. Broken curtain rod, fridge didn’t work, deadbolt lock broken, doors with mysterious brown splatter and the air vent was covered with dust. This

Reviewed on May 10, 2026

Opens in a new windowThe Westin St. Louis
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St. Louis Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the St. Louis luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in St. Louis to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in St. Louis will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in St. Louis, and plan your next opulent escape.


St. Louis hotels essential information

Accommodation
1,873 hotels
Lowest Price
$116
Highest Price
$583
Popular hotels
The Royal Sonesta Chase Park Plaza St. Louis, Ameristar Casino Resort and Spa, The Ritz-Carlton, St. Louis, Four Seasons Hotel St Louis, Clayton Plaza Hotel & Extended Stay, The Westin St. Louis, Drury Plaza Hotel St. Louis at the Arch, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Popular Luxury Stays in St. Louis

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