Explore 105 Luxury Hotels in St. Louis

Name: Ameristar Casino Resort and Spa
Price range: $215 total
Rating: 8.4

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Best Luxury Hotels in St. Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO

Fully refundableReserve now, pay when you stay

$325 nightly

$380 total

Mar 17 - Mar 18

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...

9.4/10 Exceptional! (1,001 reviews)

Top notch in every way. From the moment you walk in, it’s what you would expect from a 5-Star Hotel. Highly recommended.

Reviewed on Mar 9, 2026

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street St. Louis MO

$150 nightly

$175 total

Mar 17 - Mar 18

Total with taxes and fees

2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...

9.4/10 Exceptional! (3,354 reviews)

Wi-fi was great, location was great and staff were really nice!

Reviewed on Mar 15, 2026

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO

Fully refundableReserve now, pay when you stay

$499 nightly

$583 total

Mar 22 - Mar 23

Total with taxes and fees

This smoke-free hotel's 2 restaurants, 3 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...

9.2/10 Wonderful! (559 reviews)

Excellent staff! I was upgraded to a deluxe room from a standard at check-in. Servers and bartenders were kind and helpful and the food and drinks were delicious.

Reviewed on Mar 13, 2026

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway St. Louis MO

$184 nightly

$217 total

Apr 5 - Apr 6

Total with taxes and fees

This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...

9/10 Wonderful! (1,004 reviews)

We were not told about the $15 credit. We were also overcharged both for the remaining balance and for a meal in one of their restaurants. We were not given any receipt or told that we would be charged a different amount, also our $15 credit was not removed. Only after looking at my credit card statement ...

Reviewed on Mar 16, 2026

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO

Fully refundableReserve now, pay when you stay

$98 nightly

$114 total

Mar 22 - Mar 23

Total with taxes and fees

This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...

8.8/10 Excellent! (3,120 reviews)

Room was nice. Bathroom was great in the suite we had. I think the best part was the breakfast. Made to order omelets and waffles. We stayed here to see Zack Bryan in concert. It was a drive to the Americas Dome but we liked this hotel. We will be staying here anytime we come to St. Louis.

Reviewed on Mar 15, 2026

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St St. Louis MO

$134 nightly

$159 total

Mar 22 - Mar 23

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...

8.8/10 Excellent! (1,262 reviews)

The room was about the only good thing about this hotel. The parking was a nightmare. Ridiculously expensive. The food wasnt that good and it was very over priced. They are short staffed very badly in the restaurant so wait times were so long. The condition of the hotel was pretty trashy. It just ...

Reviewed on Mar 14, 2026

The Westin St. Louis

811 Spruce St St. Louis MO

$135 nightly

$158 total

Apr 5 - Apr 6

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...

8.6/10 Excellent! (1,005 reviews)

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Reviewed on Mar 16, 2026

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO

Fully refundableReserve now, pay when you stay

$184 nightly

$215 total

Apr 5 - Apr 6

Total with taxes and fees

This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside ...

8.4/10 Very Good! (1,009 reviews)

Room was clean and very nice! Casino was nice. We didn’t use the spa or weight room.

Reviewed on Mar 16, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway St. Louis MO

$184 nightly

$217 total

Apr 5 - Apr 6

Total with taxes and fees

9/10 Wonderful! (1,004 reviews)

5 star hotels in St. Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO

$325 nightly

$380 total

Mar 17 - Mar 18

Total with taxes and fees

9.4/10 Exceptional! (1,001 reviews)

St. Louis Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the St. Louis luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in St. Louis to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in St. Louis will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in St. Louis, and plan your next opulent escape.

St. Louis hotels essential information

Accommodation	1,887 hotels
Lowest Price	$114
Highest Price	$583
Popular hotels	The Royal Sonesta Chase Park Plaza St. Louis, Ameristar Casino Resort and Spa, The Ritz-Carlton, St. Louis, Four Seasons Hotel St Louis, Clayton Plaza Hotel & Extended Stay, The Westin St. Louis, Drury Plaza Hotel St. Louis at the Arch, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel