Explore 105 Luxury Hotels in St. Louis

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Best Luxury Hotels in St. Louis

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
$425 nightly
The price is $497 total per night from Oct 31 to Nov 1
$497 total
Oct 31 - Nov 1
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...
9.4/10 Exceptional! (1,003 reviews)
"The views from the pool were great as well as the access to the Spa with the whirlpool. Restaurant experience was underwhelming for a very nice hotel but it was kind of convenient although service was NOT fast or attentive. The room did have a comfortable bed. First room had a bath tub that was not ..."

Reviewed on Oct 5, 2025

Opens in a new windowFour Seasons Hotel St Louis
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $164 total per night from Oct 26 to Oct 27
$164 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
9.4/10 Exceptional! (3,167 reviews)
"We were very happy with the cleanliness of the hotel. The staff was very friendly and helpful! Great overall experience!"

Reviewed on Oct 16, 2025

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza, St. Louis, MO
Fully refundableReserve now, pay when you stay
$509 nightly
The price is $594 total per night from Oct 26 to Oct 27
$594 total
Oct 26 - Oct 27
Total with taxes and fees
This smoke-free hotel's 2 restaurants, 3 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
9.2/10 Wonderful! (550 reviews)
"Service is exceptional!!!"

Reviewed on Sep 2, 2025

Opens in a new windowThe Ritz-Carlton, St. Louis
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway, St. Louis, MO
Fully refundableReserve now, pay when you stay
$213 nightly
The price is $251 total per night from Nov 2 to Nov 3
$251 total
Nov 2 - Nov 3
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
8.8/10 Excellent! (1,005 reviews)
"Loud music till after midnight"

Reviewed on Oct 11, 2025

Opens in a new window The Royal Sonesta Chase Park Plaza St. Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $122 total per night from Nov 2 to Nov 3
$122 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
8.8/10 Excellent! (2,999 reviews)
"We traveled 10 hours away for an event we were going to. Clayton Hotel Plaza gave us everything we needed for our 2 night stay! When we come back to St Louis, we will be selecting this hotel again!"

Reviewed on Oct 19, 2025

Opens in a new windowClayton Plaza Hotel & Extended Stay
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St, St. Louis, MO
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $101 total per night from Oct 26 to Oct 27
$101 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.6/10 Excellent! (1,049 reviews)
"The valet is why I gave a 4/5"

Reviewed on Oct 20, 2025

Opens in a new windowMagnolia Hotel St. Louis, a Tribute Portfolio Hotel
The Westin St. Louis

The Westin St. Louis

811 Spruce St, St. Louis, MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $148 total per night from Oct 30 to Oct 31
$148 total
Oct 30 - Oct 31
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.4/10 Very Good! (1,008 reviews)
Loved our stay
"Very nice hotel close to everything. The staff is nice and friendly, the bar was nice and the bed was very comfortable. We will definitely be back!"

Reviewed on Oct 5, 2025

Opens in a new windowThe Westin St. Louis
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

1 Ameristar Blvd, St. Charles, MO
Fully refundableReserve now, pay when you stay
$192 nightly
The price is $224 total per night from Oct 26 to Oct 27
$224 total
Oct 26 - Oct 27
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside ...
8.2/10 Very Good! (1,021 reviews)
"Great place to stay.Will visit again."

Reviewed on Oct 19, 2025

Opens in a new windowAmeristar Casino Resort and Spa
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More 4 star hotels in St. Louis

5 star hotels in St. Louis

St. Louis Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the St. Louis luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in St. Louis to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in St. Louis will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in St. Louis, and plan your next opulent escape.


St. Louis hotels essential information

Accommodation
1,757 hotels
Lowest Price
$101
Highest Price
$594
Popular hotels
The Royal Sonesta Chase Park Plaza St. Louis, Ameristar Casino Resort and Spa, The Ritz-Carlton, St. Louis, Four Seasons Hotel St Louis, Clayton Plaza Hotel & Extended Stay, The Westin St. Louis, Drury Plaza Hotel St. Louis at the Arch, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Popular Luxury Stays in St. Louis

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