Book Hotels in Saint Charles, IA
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Top Saint Charles hotels

Des Lux Hotel
800 Locust St Des Moines IA
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $167 total per night from Dec 29 to Dec 30
$167 total
Dec 29 - Dec 30
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy ...
Beautiful hotel!
Reviewed on Dec 20, 2025

Hotel Fort Des Moines, Curio Collection by Hilton
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $160 total per night from Jan 4 to Jan 5
$160 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. WiFi in public areas is free. Valet parking, a business center, and a coffee shop are also ...
As always an excellent choice. Our room was gorgeous. Breakfast was fantastic. Christmas get away was better because of this hotel.
Reviewed on Dec 26, 2025

Drury Inn & Suites West Des Moines
5505 Mills Civic Pkwy West Des Moines IA
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Jan 1 to Jan 2
$112 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Staff is always great ! And of course always in tip top shape
Reviewed on Dec 25, 2025

Home2 Suites by Hilton Des Moines at Drake University
2650 University Ave. Des Moines IA
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from Jan 1 to Jan 2
$105 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Friendly staff
Reviewed on Dec 26, 2025

Fairfield Inn and Suites by Marriott Des Moines West
7225 Vista Dr West Des Moines IA
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $93 total per night from Jan 4 to Jan 5
$93 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Staff was very welcoming
Reviewed on Dec 26, 2025

Hyatt Place West Des Moines Jordan Creek
295 South 64th st West Des Moines IA
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $111 total per night from Dec 29 to Dec 30
$111 total
Dec 29 - Dec 30
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Clean, quiet, and breakfast was prob 7/10.
Reviewed on Dec 24, 2025

Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $71 total per night from Jan 4 to Jan 5
$71 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
Nothing bad to say at all
Reviewed on Dec 21, 2025

Motel 6 West Des Moines, IA
7655 Office Plaza Dr N West Des Moines IA
Fully refundableReserve now, pay when you stay
$51 nightly
The price is $57 total per night from Jan 11 to Jan 12
$57 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A terrace, a snack bar/deli, and laundry facilities are also on ...
Nice clean room, friendly staff.
Reviewed on Dec 21, 2025

AmericInn by Wyndham Des Moines Airport
1920 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $70 total per night from Jan 7 to Jan 8
$70 total
Jan 7 - Jan 8, 2026
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free self parking, and a free airport shuttle. Traveling on business? Take advantage ...
Room was great, customer service was amazing. Easy shuttle to airport.
Reviewed on Dec 22, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Saint Charles hotel reviews by fellow wanderers

Home2 Suites by Hilton Des Moines at Drake University
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Friendly staff"
A verified traveler stayed at Home2 Suites by Hilton Des Moines at Drake University
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