Book Hotels in Saint Charles, IA

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Top Saint Charles hotels

Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $200 total per night from Jun 14 to Jun 15
$200 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy ...
"The day was terrific and the parking is very convenient across the street. The breakfast was unbelievable. The weight staff was very friendly. The bartenders were amazing and all in all I would say 10 out of 10."

Reviewed on Jun 9, 2026

Opens in a new windowDes Lux Hotel
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $146 total per night from Jul 3 to Jul 4
$146 total
Jul 3 - Jul 4
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
"It was great"

Reviewed on Jun 11, 2026

Opens in a new windowHotel Fort Des Moines, Curio Collection by Hilton
Drury Inn & Suites West Des Moines

Drury Inn & Suites West Des Moines

3 out of 5
5505 Mills Civic Pkwy West Des Moines IA
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Jun 21 to Jun 22
$112 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Quick stop for 1 night. Very friendly staff and great location - it's nestled in a property like an outdoor mall. Experience a little affected by one side of the elevators being out, combined with a flock of traveling kid baseball teams, so we ended up skipping any kick back. 20 minutes from down ..."

Reviewed on Jun 11, 2026

Opens in a new windowDrury Inn & Suites West Des Moines
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $118 total per night from Jun 21 to Jun 22
$118 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Love staying here. Staff is very friendly and helpful. I don't care for the pets but that's just me"

Reviewed on Jun 12, 2026

Opens in a new windowHome2 Suites by Hilton Des Moines at Drake University
Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West

3 out of 5
7225 Vista Dr West Des Moines IA
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Jun 21 to Jun 22
$114 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Clean and friendly stuff"

Reviewed on Jun 12, 2026

Opens in a new windowFairfield Inn and Suites by Marriott Des Moines West
Fairfield Inn & Suites by Marriott Des Moines Downtown

Fairfield Inn & Suites by Marriott Des Moines Downtown

4 out of 5
207 Crocker Street Des Moines IA
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $107 total per night from Jul 5 to Jul 6
$107 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
"Very nice , clean and modern hotel in the downtown area. Fairly quiet and comfortable. We got in late and there were few places nearby to eat. Not good for walking around after dark there anyway. Great breakfast! Nice staff."

Reviewed on Jun 10, 2026

Opens in a new windowFairfield Inn & Suites by Marriott Des Moines Downtown
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $81 total per night from Jun 15 to Jun 16
$81 total
Jun 15 - Jun 16
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"Hotel was fine for a night’s stay. The bed was comfortable and the shower was hot."

Reviewed on Jun 10, 2026

Opens in a new windowDays Inn & Suites by Wyndham Des Moines Airport
Holiday Inn Downtown - Mercy Area by IHG

Holiday Inn Downtown - Mercy Area by IHG

3 out of 5
1050 6th Ave Des Moines IA
Fully refundable
$128 nightly
The price is $143 total per night from Jun 28 to Jun 29
$143 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the gym and perks like free WiFi and a free airport shuttle. A 24-hour business center, ...
"Had to change rooms because is ac units inoperable and the other noisy."

Reviewed on Jun 5, 2026

Opens in a new windowHoliday Inn Downtown - Mercy Area by IHG
Clarion Inn Des Moines Airport

Clarion Inn Des Moines Airport

3 out of 5
1810 Army Post Road Des Moines IA
Fully refundable
$65 nightly
The price is $73 total per night from Jul 5 to Jul 6
$73 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
"Service was good main lobby was good but but room is very old crappie the only outlet that worked was the bathroom, pillows were to small, the roo felt dirty"

Reviewed on Jun 12, 2026

Opens in a new windowClarion Inn Des Moines Airport
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See all available properties in Saint Charles
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Where can I find cheap hotels in Saint Charles?
At Travelocity you'll find really nice hotels in Saint Charles at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Saint Charles rather than in Saint Charles. We may find you even better rates, too.
How do I find the best Saint Charles hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Saint Charles then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Saint Charles?
The cheapest hotel in Saint Charles is $73. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Saint Charles?
There are 637 hotels in Saint Charles on Travelocity.
What are the best hotels in Saint Charles?
Saint Charles has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Saint Charles for you!
When is the best time to visit Saint Charles?
If you want the joy of a fun-filled trip in peak season, visit Saint Charles during February, April and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Saint Charles?
Based on historic data is usually the cheapest month to visit Saint Charles. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Saint Charles?
There are multiple hotels in Saint Charles that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Saint Charles. We have plenty of kid-friendly hotels in Saint Charles to choose from on Travelocity!
Why book a hotel in Saint Charles through Travelocity?
Because we have the top hotels in Saint Charles! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Saint Charles on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Saint Charles hotel reviews by fellow wanderers

Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

5 out of 5
Posted 5 hours ago
Travelocity Verified Review
"Love staying here. Staff is very friendly and helpful. I don't care for the pets but that's just me"
A verified traveler stayed at Home2 Suites by Hilton Des Moines at Drake University
Home2 Suites by Hilton Des Moines at Drake University

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