Book Hotels in Prairie Home, MO
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Top Prairie Home hotels

Drury Plaza Hotel Columbia East
3100 Interstate 70 Dr. SE Columbia MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $111 total per night from Jan 25 to Jan 26
$111 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Clean room, staff was courteous and friendly.
Reviewed on Jan 11, 2026

Drury Inn & Suites Columbia Stadium Boulevard
1000 Knipp St Columbia MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Jan 25 to Jan 26
$102 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Clean as always and the staff is always great!
Reviewed on Jan 5, 2026

Country Inn & Suites by Radisson, Columbia, MO
817 N Keene St Columbia MO
Fully refundable
$78 nightly
The price is $88 total per night from Feb 8 to Feb 9
$88 total
Feb 8 - Feb 9
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Extremely clean room with helpful appliances and the staff are very pleasant. Great value for how nice my stay was.
Reviewed on Jan 12, 2026

Best Western Plus Columbia Inn
2904 Clark Lane Columbia MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jan 19 to Jan 20
$79 total
Jan 19 - Jan 20
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
Fast and friendly
Reviewed on Jan 13, 2026

Wingate by Wyndham - Columbia
3101 Wingate Ct Columbia MO
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $92 total per night from Jan 25 to Jan 26
$92 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the express ...
Clean room, friendly staff, good breakfast, comfortable bed & pillows.
Reviewed on Jan 15, 2026

Hampton Inn & Suites Columbia at University
1225 Fellows Pl Columbia MO
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $123 total per night from Feb 8 to Feb 9
$123 total
Feb 8 - Feb 9
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the gym and free perks like buffet breakfast and free self parking. There's a hot tub ...
Room was excellent, staff was nice!! Bed was hard but everything else was great!!!
Reviewed on Jan 7, 2026

Stoney Creek Hotel Columbia
2601 S Providence Rd Columbia MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Jan 18 to Jan 19
$114 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling for business? Take advantage of the free WiFi in public areas, laundry service, and conference ...
Great staff
Reviewed on Jan 10, 2026

Wyndham Executive Center Columbia
2200 I-70 Drive SW Columbia MO
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $107 total per night from Jan 18 to Jan 19
$107 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Staff was great very nice young lady
Reviewed on Jan 13, 2026

Baymont by Wyndham Columbia, MO
2500 I 70 Dr Sw Columbia MO
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $72 total per night from Jan 25 to Jan 26
$72 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Clean room. Good healthy breakfast options. Safe parking. Friendly staff.
Reviewed on Jan 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Prairie Home hotel reviews by fellow wanderers

Wingate by Wyndham - Columbia
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Clean room, friendly staff, good breakfast, comfortable bed & pillows."
A verified traveler from Harrisburg stayed at Wingate by Wyndham - Columbia
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