Book Hotels in Lupus, MO
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Top Lupus hotels

Step Back in Time Near The Missouri River
Jamestown MO
$230 nightly
The price is $230 total per night from Jan 4 to Jan 5
$230 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This cottage features a garden, laundry facilities, and barbecue grills.
It was truly a step back in time. The house was very quaint and relaxing. Had a wonderful time with my family, thanks to Andrew for being an excellent host. Planning on coming back another trip down home!
Reviewed on Sep 24, 2025

Drury Plaza Hotel Columbia East
3100 Interstate 70 Dr. SE Columbia MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $111 total per night from Jan 4 to Jan 5
$111 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Rooms were clean! Staff was upbeat and enthusiastic which was very nice to see! My first time at a Drury, but not my last!
Reviewed on Dec 15, 2025

Quiet Riverfront Cottage on Missouri River
Jamestown MO
This cottage features a garden, laundry facilities, and barbecue grills.
Birthday getaway
Very cute place. Enjoyed our walk down to the river and watching the water flow
Reviewed on Mar 7, 2025

Country Inn & Suites by Radisson, Columbia, MO
817 N Keene St Columbia MO
Fully refundable
$78 nightly
The price is $88 total per night from Jan 14 to Jan 15
$88 total
Jan 14 - Jan 15, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Everything was great
Reviewed on Dec 20, 2025

Wingate by Wyndham - Columbia
3101 Wingate Ct Columbia MO
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $92 total per night from Dec 31 to Jan 1
$92 total
Dec 31 - Jan 1, 2026
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the express ...
Clean room, helpful staff, room was noisy at night due to traffic outside but other than that great for the price.
Reviewed on Dec 22, 2025

Best Western Plus Columbia Inn
2904 Clark Lane Columbia MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Dec 29 to Dec 30
$79 total
Dec 29 - Dec 30
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
Yes room spotless
Reviewed on Dec 21, 2025

Stoney Creek Hotel Columbia
2601 S Providence Rd Columbia MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Dec 28 to Dec 29
$114 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling for business? Take advantage of the free WiFi in public areas, laundry service, and conference ...
noce atmosphere
Reviewed on Dec 19, 2025

Wyndham Executive Center Columbia
2200 I-70 Drive SW Columbia MO
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $96 total per night from Jan 25 to Jan 26
$96 total
Jan 25 - Jan 26, 2026
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Location. Big room.
Reviewed on Dec 16, 2025

Ramada by Wyndham Columbia
901 Conley Rd Columbia MO
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $73 total per night from Dec 26 to Dec 27
$73 total
Dec 26 - Dec 27
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Fine
Reviewed on Dec 18, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Lupus hotel reviews by fellow wanderers

Wingate by Wyndham - Columbia
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Clean room, helpful staff, room was noisy at night due to traffic outside but other than that great for the price."
A verified traveler stayed at Wingate by Wyndham - Columbia
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