Book Hotels in Lupus, MO
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Top Lupus hotels

Step Back in Time Near The Missouri River
Jamestown MO
$281 nightly
The price is $298 total per night from Jun 8 to Jun 9
$298 total
Jun 8 - Jun 9
Total with taxes and fees
This cottage features a garden, laundry facilities, and barbecue grills.
Quaint town. Old house very nicely decorated and clean. We grilled both nights and then sat out on the front porch. Awesome
Reviewed on Apr 13, 2026

Drury Plaza Hotel Columbia East
3100 Interstate 70 Dr. SE Columbia MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from May 24 to May 25
$102 total
May 24 - May 25
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Comfortable bed!
Reviewed on May 11, 2026

Quiet Riverfront Cottage on Missouri River
Jamestown MO
$185 nightly
The price is $197 total per night from Jun 8 to Jun 9
$197 total
Jun 8 - Jun 9
Total with taxes and fees
This cottage features a garden, laundry facilities, and barbecue grills.
Birthday getaway
Very cute place. Enjoyed our walk down to the river and watching the water flow
Reviewed on Mar 7, 2025

Country Inn & Suites by Radisson, Columbia, MO
817 N Keene St Columbia MO
Fully refundable
$83 nightly
The price is $93 total per night from Jun 7 to Jun 8
$93 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Room was extremely clean pool and hot tub was amazing breakfast was great
Reviewed on May 16, 2026

Wingate by Wyndham - Columbia
3101 Wingate Ct Columbia MO
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $92 total per night from Jun 7 to Jun 8
$92 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
Breakfast offered a good selection. Easy access off freeway. Quiet
Reviewed on May 15, 2026

Stoney Creek Hotel Columbia
2601 S Providence Rd Columbia MO
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $134 total per night from May 17 to May 18
$134 total
May 17 - May 18
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling for business? Take advantage of the free WiFi in public areas, laundry service, and conference ...
This has unfortunately gone down here. Had our wedding reception here 17 years ago and have stayed multiple times since and has been wonderful. The edges of carpets in hall are visibly dirty. We tried 3 rooms- all were visibly filthy around the edges of carpet- area by microwave had broken tiles, ...
Reviewed on May 16, 2026

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination
100 Isle of Capri Blvd Boonville MO
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $101 total per night from May 18 to May 19
$101 total
May 18 - May 19
Total with taxes and fees
A casino, 2 restaurants, and a 24-hour gym are all featured at this hotel. Traveling on business? Take advantage of the 3 conference rooms, along with free WiFi ...
Casino
Reviewed on May 14, 2026

Baymont by Wyndham Columbia, MO
2500 I 70 Dr Sw Columbia MO
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $66 total per night from May 24 to May 25
$66 total
May 24 - May 25
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
We stopped for the night while traveling cross country. Clean room, full breakfast area, available staff, and ample parking. I would stay here again.
Reviewed on May 12, 2026

Wyndham Executive Center Columbia
2200 I-70 Drive SW Columbia MO
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $127 total per night from May 21 to May 22
$127 total
May 21 - May 22
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Very underrated for the price. Great hotel overall.
Reviewed on May 10, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Lupus hotel reviews by fellow wanderers

Best Western Plus Columbia Inn
4 out of 5
Posted 5 hours ago
Travelocity Verified Review
"The room was very clean. It came equipped with a small refrigerator. I fixed the toilet from leaking all night long. The chain to the flapper would get caught underneath and cause the toilet to run all night long. It never happened again. The parking lot was being repainted while we were there. It was an inconvenience, but shows that the owner was maintaining this hotel. The indoor pool was clean,but the odor of chlorine was too strong for me. Most of the cleaning staff only spoke Spanish. All of the front desk staff were great helpful people. The man who takes care of the breakfast is very attentive and never allowed anything to be depleted. My only complaint is that the eggs are made from a yellow liquid inside a plastic bag. The bag with the egg liquid is microwaved in the bag. Everything is kept clean and tidy for breakfast. He does a great job.
One other complaint is the air conditioner goes into some type of power saving mode in the middle of the night that caused me to wake up hot."
A verified traveler stayed at Best Western Plus Columbia Inn
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