Book Hotels in Lupus, MO
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top Lupus hotels

Step Back in Time Near The Missouri River
Jamestown MO
$218 nightly
The price is $218 total per night from Dec 15 to Dec 16
$218 total
Dec 15 - Dec 16
Total with taxes and fees
This cottage features a garden, laundry facilities, and barbecue grills.
It was truly a step back in time. The house was very quaint and relaxing. Had a wonderful time with my family, thanks to Andrew for being an excellent host. Planning on coming back another trip down home!
Reviewed on Sep 24, 2025

Drury Plaza Hotel Columbia East
3100 Interstate 70 Dr. SE Columbia MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Dec 25 to Dec 26
$106 total
Dec 25 - Dec 26
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Everything was what we hoped for?
Reviewed on Dec 6, 2025

Quiet Riverfront Cottage on Missouri River
Jamestown MO
$177 nightly
The price is $177 total per night from Dec 12 to Dec 13
$177 total
Dec 12 - Dec 13
Total with taxes and fees
This cottage features a garden, laundry facilities, and barbecue grills.
Birthday getaway
Very cute place. Enjoyed our walk down to the river and watching the water flow
Reviewed on Mar 7, 2025

Country Inn & Suites by Radisson, Columbia, MO
817 N Keene St Columbia MO
Fully refundable
$78 nightly
The price is $88 total per night from Dec 31 to Jan 1
$88 total
Dec 31 - Jan 1, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Property was clean! Room was excellent and comfortable. Easy check in. Staff was friendly.
Reviewed on Dec 7, 2025

Best Western Plus Columbia Inn
2904 Clark Lane Columbia MO
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $81 total per night from Dec 18 to Dec 19
$81 total
Dec 18 - Dec 19
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
Everything was very good.
Reviewed on Dec 8, 2025

Stoney Creek Hotel Columbia
2601 S Providence Rd Columbia MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Dec 14 to Dec 15
$114 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling for business? Take advantage of the free WiFi in public areas, laundry service, and conference ...
I love staying at Stoney Creek. It is always clean. The staff is great. This was the first time that we stayed and our bed in room 153 was not comfortable. The head of the bed was couple inches lower than the foot. So my husband rotated mattress but did not help. Was a restless night.
Reviewed on Dec 9, 2025

Wyndham Executive Center Columbia
2200 I-70 Drive SW Columbia MO
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $109 total per night from Jan 2 to Jan 3
$109 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Awesome service
Reviewed on Dec 8, 2025

Baymont by Wyndham Columbia, MO
2500 I 70 Dr Sw Columbia MO
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $62 total per night from Dec 17 to Dec 18
$62 total
Dec 17 - Dec 18
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Was a very late stop. Was glad the front desk person didnt mind checking us in at 4am with a smile on there face.
Reviewed on Dec 7, 2025

Ramada by Wyndham Columbia
901 Conley Rd Columbia MO
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $69 total per night from Dec 14 to Dec 15
$69 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Breakfast wasn’t bad but hot food was still cold at 615 am so was just being put out room was very very warm
Reviewed on Dec 8, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Lupus hotel reviews by fellow wanderers

Wyndham Executive Center Columbia
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Awesome service "
A verified traveler stayed at Wyndham Executive Center Columbia
Explore More Ways to Travel with Travelocity
- Apartments in Wooldridge
- B&B in Wooldridge
- Eagle Bluffs Conservation Area Hotels
- Hotels near Serenity Valley Winery
- Speed Hotels
- Prairie Home Hotels
- Hotels near Finger Lakes State Park
- Hotels near Mizzou Arena
- Hotels near Columbia Regional
- Hotels near Main Street Baptist Church
- Windsor Place Hotels
- Hotels near Rock Bridge Memorial State Park
- Hotels with Pools in Boone County
- Boone County Hotels
- Thornbrook Hotels
- Cabins in Rocheport
- Rocheport Hotels
- Vacation Homes in Rocheport
- Hotels near Stephens College
- Hartsburg Hotels
- Farmstay in Jamestown
- Cabins in Jamestown
- Hotels near Daniel Boone Regional Library
- Hotels near Harley Park
- Hotels near Lions Park Aquatic Center
- 3 Star Hotels in Columbia
- 4 Star Hotels in Columbia
- Apartments in Columbia
- B&B in Columbia
- Cabins in Columbia
- Pod Hotels in Columbia
- Condos in Columbia
- Extended Stay Hotels in Columbia
- Guest Houses in Columbia
- Adults Only Resorts & in Columbia
- Best Western Hotels in Columbia
- Boutique Hotels in Columbia
- Casino Resorts & in Columbia
- Cheap Hotels in Columbia
- Convention Center Hotels in Columbia
- Kid Friendly Hotels in Columbia
- Gay Friendly Hotels in Columbia
- Golf Resorts & in Columbia
- Historic Hotels in Columbia
- Hotels with Pools in Columbia
- Hotels with Balconies in Columbia
- Hotels with Bar in Columbia
- Hotels with Hot Tubs in Columbia
- Hotels with an Indoor Pool in Columbia
- Hotels with Waterslides in Columbia
- Luxury Hotels in Columbia
- Pet Friendly Hotels in Columbia
- Romantic Getaways & Hotels in Columbia
- Spa Resorts & in Columbia
- Waterpark Hotels and Resorts in Columbia
- Hotel Wedding Venues Hotels in Columbia
- Winery Hotels in Columbia
- Columbia Hotels
- Motels in Columbia
- Vacation Homes in Columbia
- Hotels near Warm Springs Ranch
- Hotels near Women's and Children's Hospital
- Boonville Hotels
- Hotels near Isle of Capri Casino
- New Franklin Hotels
- Hotels near Faurot Field at Memorial Stadium
- Hotels near University of Missouri
- California Hotels
- Hotels near Columbia College
- Hotels near Columbia Mall
- 4 Star Hotels in Ashland
- Cabins in Ashland
- Condos in Ashland
- Ashland Hotels
- Motels in Ashland
- Vacation Homes in Ashland
- Flights from Columbia Regional
- American Airlines Denver (DEN) to Columbia (COU) flights
- American Airlines Nashville (BNA) to Columbia (COU) flights
- Delta Atlanta (ATL) to Columbia (COU) flights
- Flights from Cincinnati (CVG) to Columbia (COU)
- Flights from Dallas (DFW) to Columbia (COU)
- Flights from Chicago (ORD) to Columbia (COU)
- Flights from Phoenix (PHX) to Columbia (COU)
- Flights from St. Louis (STL) to Columbia (COU)
- Flights from Fayetteville (XNA) to Columbia (COU)
- Flights to Columbia
- Flights to Ashland






