Book Hotels in Lupus, MO
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top Lupus hotels

Step Back in Time Near The Missouri River
Jamestown MO
$237 nightly
The price is $237 total per night from Jan 15 to Jan 16
$237 total
Jan 15 - Jan 16
Total with taxes and fees
This cottage features a garden, laundry facilities, and barbecue grills.
Had a great time. The place was big enough for our family holiday gathering and the Kitty is the best.
Reviewed on Dec 22, 2025

Drury Plaza Hotel Columbia East
3100 Interstate 70 Dr. SE Columbia MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $111 total per night from Jan 18 to Jan 19
$111 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Clean room, staff was courteous and friendly.
Reviewed on Jan 11, 2026

Quiet Riverfront Cottage on Missouri River
Jamestown MO
This cottage features a garden, laundry facilities, and barbecue grills.
Birthday getaway
Very cute place. Enjoyed our walk down to the river and watching the water flow
Reviewed on Mar 7, 2025

Country Inn & Suites by Radisson, Columbia, MO
817 N Keene St Columbia MO
Fully refundable
$78 nightly
The price is $88 total per night from Feb 2 to Feb 3
$88 total
Feb 2 - Feb 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Conveniently located property. Room was clean and spacious. Bed was comfortable. Breakfast was awesome. Dining options nearby.
Reviewed on Jan 5, 2026

Best Western Plus Columbia Inn
2904 Clark Lane Columbia MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jan 16 to Jan 17
$79 total
Jan 16 - Jan 17
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
Clean room. Staff was helpful. The toilet was clogged and they fixed it quickly. Breakfast was solid.
Reviewed on Jan 4, 2026

Wingate by Wyndham - Columbia
3101 Wingate Ct Columbia MO
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $92 total per night from Jan 19 to Jan 20
$92 total
Jan 19 - Jan 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the express ...
Room and bathroom nice and clean. Bed and pillows fluffy and comfortable. All around a good nights stay at a convenient location.
Reviewed on Jan 9, 2026

Stoney Creek Hotel Columbia
2601 S Providence Rd Columbia MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Jan 18 to Jan 19
$114 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling for business? Take advantage of the free WiFi in public areas, laundry service, and conference ...
Staff was nice
Reviewed on Jan 5, 2026

Wyndham Executive Center Columbia
2200 I-70 Drive SW Columbia MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Jan 14 to Jan 15
$106 total
Jan 14 - Jan 15
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Everything was great except for the construction going on at the front of the hotel.
Reviewed on Jan 6, 2026

Baymont by Wyndham Columbia, MO
2500 I 70 Dr Sw Columbia MO
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $66 total per night from Jan 19 to Jan 20
$66 total
Jan 19 - Jan 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Clean room. Good healthy breakfast options. Safe parking. Friendly staff.
Reviewed on Jan 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Lupus hotel reviews by fellow wanderers

Drury Plaza Hotel Columbia East
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Clean room, staff was courteous and friendly. "
A verified traveler stayed at Drury Plaza Hotel Columbia East
Explore More Ways to Travel with Travelocity
- Apartments in Wooldridge
- B&B in Wooldridge
- Eagle Bluffs Conservation Area Hotels
- Hotels near Serenity Valley Winery
- Speed Hotels
- Prairie Home Hotels
- Hotels near Finger Lakes State Park
- Hotels near Mizzou Arena
- Hotels near Columbia Regional
- Hotels near Main Street Baptist Church
- Windsor Place Hotels
- Hotels near Rock Bridge Memorial State Park
- Hotels with Pools in Boone County
- Boone County Hotels
- Thornbrook Hotels
- Cabins in Rocheport
- Rocheport Hotels
- Vacation Homes in Rocheport
- Hotels near Stephens College
- Hartsburg Hotels
- Farmstay in Jamestown
- Cabins in Jamestown
- Hotels near Daniel Boone Regional Library
- Hotels near Harley Park
- Hotels near Lions Park Aquatic Center
- 3 Star Hotels in Columbia
- 4 Star Hotels in Columbia
- Apartments in Columbia
- B&B in Columbia
- Cabins in Columbia
- Pod Hotels in Columbia
- Condos in Columbia
- Extended Stay Hotels in Columbia
- Guest Houses in Columbia
- Adults Only Resorts & in Columbia
- Best Western Hotels in Columbia
- Boutique Hotels in Columbia
- Casino Resorts & in Columbia
- Cheap Hotels in Columbia
- Convention Center Hotels in Columbia
- Kid Friendly Hotels in Columbia
- Gay Friendly Hotels in Columbia
- Golf Resorts & in Columbia
- Historic Hotels in Columbia
- Hotels with Pools in Columbia
- Hotels with Balconies in Columbia
- Hotels with Bar in Columbia
- Hotels with Hot Tubs in Columbia
- Hotels with an Indoor Pool in Columbia
- Hotels with Waterslides in Columbia
- Luxury Hotels in Columbia
- Pet Friendly Hotels in Columbia
- Romantic Getaways & Hotels in Columbia
- Spa Resorts & in Columbia
- Waterpark Hotels and Resorts in Columbia
- Hotel Wedding Venues Hotels in Columbia
- Winery Hotels in Columbia
- Columbia Hotels
- Motels in Columbia
- Vacation Homes in Columbia
- Hotels near Warm Springs Ranch
- Hotels near Women's and Children's Hospital
- Boonville Hotels
- Hotels near Isle of Capri Casino
- New Franklin Hotels
- Hotels near Faurot Field at Memorial Stadium
- Hotels near University of Missouri
- California Hotels
- Hotels near Columbia College
- Hotels near Columbia Mall
- 4 Star Hotels in Ashland
- Cabins in Ashland
- Condos in Ashland
- Ashland Hotels
- Motels in Ashland
- Vacation Homes in Ashland
- Flights from Columbia Regional
- American Airlines Denver (DEN) to Columbia (COU) flights
- American Airlines Nashville (BNA) to Columbia (COU) flights
- Delta Atlanta (ATL) to Columbia (COU) flights
- Flights from Cincinnati (CVG) to Columbia (COU)
- Flights from Dallas (DFW) to Columbia (COU)
- Flights from Chicago (ORD) to Columbia (COU)
- Flights from Phoenix (PHX) to Columbia (COU)
- Flights from St. Louis (STL) to Columbia (COU)
- Flights from Fayetteville (XNA) to Columbia (COU)
- Flights to Columbia
- Flights to Ashland






