Book Hotels in Lupus, MO
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Top Lupus hotels

Step Back in Time Near The Missouri River
Jamestown MO
$258 nightly
The price is $274 total per night from Apr 14 to Apr 15
$274 total
Apr 14 - Apr 15
Total with taxes and fees
This cottage features a garden, laundry facilities, and barbecue grills.
Had a great time. The place was big enough for our family holiday gathering and the Kitty is the best.
Reviewed on Dec 22, 2025

Drury Plaza Hotel Columbia East
3100 Interstate 70 Dr. SE Columbia MO
$94 nightly
The price is $106 total per night from Apr 12 to Apr 13
$106 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
This hotel was fantastic! We will definitely stay again!!! Food and service were phenomenal! So easy and close to get on and off 70 to get to hotel We normally book with Hilton but this was an even better experience!
Reviewed on Mar 26, 2026

Quiet Riverfront Cottage on Missouri River
Jamestown MO
$186 nightly
The price is $198 total per night from Mar 30 to Mar 31
$198 total
Mar 30 - Mar 31
Total with taxes and fees
This cottage features a garden, laundry facilities, and barbecue grills.
Birthday getaway
Very cute place. Enjoyed our walk down to the river and watching the water flow
Reviewed on Mar 7, 2025

Country Inn & Suites by Radisson, Columbia, MO
817 N Keene St Columbia MO
Fully refundable
$85 nightly
The price is $96 total per night from Apr 5 to Apr 6
$96 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
The bed was too tall and the toilet was too short for seniors. Breakfast was great.
Reviewed on Mar 28, 2026

Wingate by Wyndham - Columbia
3101 Wingate Ct Columbia MO
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $97 total per night from Apr 5 to Apr 6
$97 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
Excellent stay
Reviewed on Mar 26, 2026

Best Western Plus Columbia Inn
2904 Clark Lane Columbia MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Apr 1 to Apr 2
$79 total
Apr 1 - Apr 2
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
Clean room. Staff was very nice and helpful. Good breakfast.
Reviewed on Mar 27, 2026

Stoney Creek Hotel Columbia
2601 S Providence Rd Columbia MO
Fully refundableReserve now, pay when you stay
$112 nightly
The price is $127 total per night from Apr 26 to Apr 27
$127 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling for business? Take advantage of the free WiFi in public areas, laundry service, and conference ...
We made a reservation a few months before our trip and when we got to the hotel, we were told they overbooked so we had no room. Since we booked through a third party we were the ones to get cut. 6 hours away from home and we were scrambling to find somewhere to stay
Reviewed on Mar 27, 2026

Baymont by Wyndham Columbia, MO
2500 I 70 Dr Sw Columbia MO
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $72 total per night from Apr 5 to Apr 6
$72 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Very friendly staff and clean room.
Reviewed on Mar 25, 2026

Wyndham Executive Center Columbia
2200 I-70 Drive SW Columbia MO
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $127 total per night from Mar 29 to Mar 30
$127 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
The room was out dated.
Reviewed on Mar 23, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Lupus hotel reviews by fellow wanderers

Country Inn & Suites by Radisson, Columbia, MO
4 out of 5
Posted 9 hours ago
Travelocity Verified Review
"The bed was too tall and the toilet was too short for seniors. Breakfast was great."
A verified traveler stayed at Country Inn & Suites by Radisson, Columbia, MO
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