Book Hotels in Lupus, MO
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Top Lupus hotels

Step Back in Time Near The Missouri River
Jamestown
$286 nightly
The price is $286 total per night from Sep 28 to Sep 29
$286 total
Sep 28 - Sep 29
Total with taxes and fees
This cottage features a garden, laundry facilities, and barbecue grills.
"It was very beautiful well stocked, and the owner was very mindful and considerate as to what people needed to be well accommodated and comfortable. I like that."
Reviewed on Sep 17, 2025

Drury Plaza Hotel Columbia East
3100 Interstate 70 Dr. SE, Columbia, MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Oct 19 to Oct 20
$106 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Always a great place to stay when in CoMo."
Reviewed on Sep 22, 2025

Quiet Riverfront Cottage on Missouri River
Jamestown
$186 nightly
The price is $186 total per night from Sep 28 to Sep 29
$186 total
Sep 28 - Sep 29
Total with taxes and fees
This cottage features a garden, laundry facilities, and barbecue grills.
Birthday getaway
"Very cute place. Enjoyed our walk down to the river and watching the water flow"
Reviewed on Mar 7, 2025

Country Inn & Suites by Radisson, Columbia, MO
817 N Keene St, Columbia, MO
Fully refundable
$83 nightly
The price is $93 total per night from Oct 9 to Oct 10
$93 total
Oct 9 - Oct 10
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"Safe, quite, friendly staff, nice room."
Reviewed on Sep 24, 2025

Wingate by Wyndham - Columbia
3101 Wingate Ct, Columbia, MO
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $99 total per night from Oct 2 to Oct 3
$99 total
Oct 2 - Oct 3
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"We only stayed one night. Ryan, the manager, was so nice after I messed up the reservation. The hotel was very accommodating. There's a lot of road noise, but it did not prevent us from getting a good night's sleep. Would stay here again."
Reviewed on Sep 17, 2025

Best Western Plus Columbia Inn
2904 Clark Lane, Columbia, MO
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $81 total per night from Oct 6 to Oct 7
$81 total
Oct 6 - Oct 7
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
"Amazing stay easy access to food"
Reviewed on Sep 21, 2025

Stoney Creek Hotel Columbia
2601 S Providence Rd, Columbia, MO
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $134 total per night from Sep 28 to Sep 29
$134 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling for business? Take advantage of the free WiFi in public areas, laundry service, and conference ...
"Unique decor, home-like atmosphere"
Reviewed on Sep 21, 2025

Wyndham Executive Center Columbia
2200 I-70 Drive SW, Columbia, MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $111 total per night from Oct 5 to Oct 6
$111 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"One night stay and had 1am check in. But the staff was so nice, got us to our room quickly. Clean room, good beds."
Reviewed on Sep 21, 2025

Baymont by Wyndham Columbia, MO
2500 I 70 Dr Sw, Columbia, MO
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $69 total per night from Oct 2 to Oct 3
$69 total
Oct 2 - Oct 3
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"The staff was very friendly! The bed was very nice! Our room seemed to be newly updated. Overall very clean except I happened to notice what appeared to be soda splatters on the under side of the lamp shade, I can’t say I would ever notice that in my own house. My biggest issue was the humidity in ..."
Reviewed on Sep 22, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Lupus hotel reviews by fellow wanderers

Country Inn & Suites by Radisson, Columbia, MO
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Safe, quite, friendly staff, nice room."
A verified traveler stayed at Country Inn & Suites by Radisson, Columbia, MO
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