Book Hotels in Lupus, MO

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight
Apr 11 - Apr 12
Tomorrow
Apr 12 - Apr 13
Next weekend
Apr 17 - Apr 19
In two weeks
Apr 24 - Apr 26

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Lupus hotels

Step Back in Time Near The Missouri River

Step Back in Time Near The Missouri River

Jamestown MO
$258 nightly
The price is $274 total per night from Apr 14 to Apr 15
$274 total
Apr 14 - Apr 15
Total with taxes and fees
This cottage features a garden, laundry facilities, and barbecue grills.
Had a great time. The place was big enough for our family holiday gathering and the Kitty is the best.

Reviewed on Dec 22, 2025

Opens in a new windowStep Back in Time Near The Missouri River
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

3 out of 5
3100 Interstate 70 Dr. SE Columbia MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from May 3 to May 4
$106 total
May 3 - May 4
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Positives- free breakfast and light dinner buffet available including one free alcoholic drink daily. Friendly staff. Clean enough. Good facility for conference (why I was there). Negatives- I like to walk a lot in a new place and there is VERY little that is walkable. I walked from downtown Columbia/Univ ...

Reviewed on Apr 10, 2026

Opens in a new windowDrury Plaza Hotel Columbia East
Quiet Riverfront Cottage on Missouri River

Quiet Riverfront Cottage on Missouri River

Jamestown MO
$185 nightly
The price is $197 total per night from Apr 12 to Apr 13
$197 total
Apr 12 - Apr 13
Total with taxes and fees
This cottage features a garden, laundry facilities, and barbecue grills.
Birthday getaway
Very cute place. Enjoyed our walk down to the river and watching the water flow

Reviewed on Mar 7, 2025

Opens in a new windowQuiet Riverfront Cottage on Missouri River
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

2.5 out of 5
817 N Keene St Columbia MO
Fully refundable
$87 nightly
The price is $98 total per night from May 3 to May 4
$98 total
May 3 - May 4
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
This property was definitely a bargain at the price point I was able to book my single room.

Reviewed on Apr 11, 2026

Opens in a new windowCountry Inn & Suites by Radisson, Columbia, MO
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

3 out of 5
3101 Wingate Ct Columbia MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Apr 19 to Apr 20
$102 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
As always, clean room, nice staff.

Reviewed on Apr 11, 2026

Opens in a new windowWingate by Wyndham - Columbia
Best Western Plus Columbia Inn

Best Western Plus Columbia Inn

2.5 out of 5
2904 Clark Lane Columbia MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Apr 19 to Apr 20
$79 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
The hotel was ok. Room 114 was not good. Stains on the chairs, bed was basically a bowl, next door to exercise room, and a huge air conditioner unit outside the window. I’d also like to thank the enthusiastic athlete that felt 3:30 am was a good time to run on the treadmill!

Reviewed on Apr 9, 2026

Opens in a new windowBest Western Plus Columbia Inn
Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

2.5 out of 5
2601 S Providence Rd Columbia MO
Fully refundableReserve now, pay when you stay
$112 nightly
The price is $127 total per night from Apr 26 to Apr 27
$127 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling for business? Take advantage of the free WiFi in public areas, laundry service, and conference ...
Clean quiet room. Had a dog with us and we had easy access to outside facilities.

Reviewed on Apr 8, 2026

Opens in a new windowStoney Creek Hotel Columbia
Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

2.5 out of 5
2500 I 70 Dr Sw Columbia MO
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $72 total per night from Apr 19 to Apr 20
$72 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Nice room. Comfy bed, nice bed linens. Clean. Towels should be replaced. Would stay here again

Reviewed on Apr 9, 2026

Opens in a new windowBaymont by Wyndham Columbia, MO
Wyndham Executive Center Columbia

Wyndham Executive Center Columbia

3.5 out of 5
2200 I-70 Drive SW Columbia MO
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $127 total per night from Apr 12 to Apr 13
$127 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Took over an hour to check in because internet was down. Staff was apologetic but just surprised there was no other way to check in.

Reviewed on Apr 10, 2026

Opens in a new windowWyndham Executive Center Columbia
Don't see what you're looking for?
See all available properties in Lupus
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Lupus?
From cool amenities to bigger rooms, kid-friendly hotels come with features that can help transform an everyday family vacation into a sensational one. These Lupus options make vacationing with young ones easier: You'll be well looked after at Quiet Riverfront Cottage on Missouri River. It comes with a playground, animal viewing activities and a flair for making families feel at home. Alternatively, spend your Lupus break at Step Back in Time Near The Missouri River. Take advantage of a firepit, a fireplace and more here.
Where can I find cheap hotels in Lupus?
At Travelocity you'll find really nice hotels in Lupus at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Lupus rather than in Lupus. We may find you even better rates, too.
How do I find the best Lupus hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Lupus then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Lupus?
The cheapest hotel in Lupus is $72. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Lupus?
There are 246 hotels in Lupus on Travelocity.
What are the best hotels in Lupus?
Lupus has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Lupus for you!
When is the best time to visit Lupus?
If you want the joy of a fun-filled trip in peak season, visit Lupus during May, June and July. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Lupus?
Based on historic data is usually the cheapest month to visit Lupus. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Lupus?
There are multiple hotels in Lupus that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Lupus. We have plenty of kid-friendly hotels in Lupus to choose from on Travelocity!
Why book a hotel in Lupus through Travelocity?
Because we have the top hotels in Lupus! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Lupus on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Lupus hotel reviews by fellow wanderers

Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

5 out of 5
Posted 3 hours ago
Travelocity Verified Review
"This property was definitely a bargain at the price point I was able to book my single room."
A verified traveler stayed at Country Inn & Suites by Radisson, Columbia, MO
Country Inn & Suites by Radisson, Columbia, MO

Explore More Ways to Travel with Travelocity