Book Hotels in Prairie Home, MO
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Top Prairie Home hotels

Drury Plaza Hotel Columbia East
3100 Interstate 70 Dr. SE Columbia MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Jul 12 to Jul 13
$106 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Excellent hotel. Modern amenities. Breakfast very on point, however I need all staff members serving and preparing foods to where hair nets. Also, please make to-go silverware available without having to request it."
Reviewed on Jul 4, 2026

Country Inn & Suites by Radisson, Columbia, MO
817 N Keene St Columbia MO
Fully refundable
$80 nightly
The price is $90 total per night from Jul 26 to Jul 27
$90 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"Good hotel. We’ll stay here again"
Reviewed on Jul 4, 2026

Wingate by Wyndham - Columbia
3101 Wingate Ct Columbia MO
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $92 total per night from Jul 12 to Jul 13
$92 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
"Staff is very helpful and kind. Room was clean. We have used this hotel several times. Price is competitive."
Reviewed on Jul 3, 2026

Best Western Plus Columbia Inn
2904 Clark Lane Columbia MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jul 13 to Jul 14
$79 total
Jul 13 - Jul 14
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
"Great room, very convenient locations. Everything was very clean. Staff friendly and helpful."
Reviewed on Jul 4, 2026

Tru By Hilton Columbia South
4401 S Ponderosa Street Columbia MO
$85 nightly
The price is $97 total per night from Aug 2 to Aug 3
$97 total
Aug 2 - Aug 3
Total with taxes and fees
A 24-hour gym is featured at this hotel, along with free self parking. Guests will appreciate free perks like buffet breakfast and WiFi in public areas. Staff ...
"One day trip. Clean room, good breakfast!"
Reviewed on Jun 30, 2026

Stoney Creek Hotel Columbia
2601 S Providence Rd Columbia MO
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $134 total per night from Jul 12 to Jul 13
$134 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling for business? Take advantage of the free WiFi in public areas, laundry service, and conference ...
"it's a really great place to stay rooms were nice and clean the building itself is very modern looking their outdoor theme gives the hotel a very relaxing and calming feeling you'll love the decor staff was very friendly and helpful out of 10 stars i would give it a 9 the reason why their tv was ..."
Reviewed on Jul 1, 2026

Wyndham Executive Center Columbia
2200 I-70 Drive SW Columbia MO
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $152 total per night from Jul 6 to Jul 7
$152 total
Jul 6 - Jul 7
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Overall an okay hotel to stay at for a night or two. Had to wait 30 mins past check in time to check in because they said a room wasn’t available."
Reviewed on Jul 1, 2026

Hotel Blu
3402 Interstate 70 Dr SE Columbia MO
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $66 total per night from Jul 6 to Jul 7
$66 total
Jul 6 - Jul 7
Total with taxes and fees
An indoor pool, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. A grocery/convenience store, a lobby fireplace, ...
"The property was wonderful. The staff was polite and accommodating. The room was very nice and spacious. The issues I experienced were with Expedia, not the hotel. I couldn’t have asked for a better hotel experience."
Reviewed on Jul 3, 2026

Baymont by Wyndham Columbia, MO
2500 I 70 Dr Sw Columbia MO
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $72 total per night from Jul 12 to Jul 13
$72 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Prairie Home hotel reviews by fellow wanderers

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination
5 out of 5
Posted 7 hours ago
Travelocity Verified Review
"Had a great time"
A verified traveler stayed at Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination
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