Book Hotels in Prairie Home, MO
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Top Prairie Home hotels

Drury Plaza Hotel Columbia East
3100 Interstate 70 Dr. SE Columbia MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Jul 19 to Jul 20
$106 total
Jul 19 - Jul 20
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Very Nice overall"
Reviewed on Jun 20, 2026

Wingate by Wyndham - Columbia
3101 Wingate Ct Columbia MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $101 total per night from Jun 28 to Jun 29
$101 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
"Great pool and hot tub. Neat location. Clean room. Amazing A/C. Good parking. Great breakfast. Amazing stay!!!"
Reviewed on Jun 21, 2026

Country Inn & Suites by Radisson, Columbia, MO
817 N Keene St Columbia MO
Fully refundable
$83 nightly
The price is $93 total per night from Jul 12 to Jul 13
$93 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"Great stay in the middle of a lot of options to eat"
Reviewed on Jun 20, 2026

Best Western Plus Columbia Inn
2904 Clark Lane Columbia MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jun 28 to Jun 29
$79 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
"Breakfast wasn’t bad. It was a little delayed because I guess whatever reasons I have no idea ID but anyways I didn’t happen until about 6: 15 in the morning, but that’s OK. Everything else was nice. The place was quiet place was clean and the staff was good. Everybody was helpful and no problems ..."
Reviewed on Jun 20, 2026

Baymont by Wyndham Columbia, MO
2500 I 70 Dr Sw Columbia MO
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $72 total per night from Jun 28 to Jun 29
$72 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Walking distance to the Route 66 museum. Staff was very personable. Nice room. Good water pressure for shower."
Reviewed on Jun 17, 2026

Wyndham Executive Center Columbia
2200 I-70 Drive SW Columbia MO
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $141 total per night from Jun 22 to Jun 23
$141 total
Jun 22 - Jun 23
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"No breakfast included is an archaic business model"
Reviewed on Jun 19, 2026

Ramada by Wyndham Columbia
901 Conley Rd Columbia MO
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $72 total per night from Jun 28 to Jun 29
$72 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"never again!"
Reviewed on Jun 19, 2026

Hotel Blu
3402 Interstate 70 Dr SE Columbia MO
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $69 total per night from Jun 23 to Jun 24
$69 total
Jun 23 - Jun 24
Total with taxes and fees
An indoor pool, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. A grocery/convenience store, a lobby fireplace, ...
"Transitioning from Motel 6 to Hotel Blu but much better than a Motel 6. Staff was helping and flexible when I asked for late check-out then ended up leaving in time, they didn’t charge me."
Reviewed on Jun 20, 2026

Stoney Creek Hotel Columbia
2601 S Providence Rd Columbia MO
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $127 total per night from Jun 22 to Jun 23
$127 total
Jun 22 - Jun 23
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling for business? Take advantage of the free WiFi in public areas, laundry service, and conference ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Prairie Home hotel reviews by fellow wanderers

Wingate by Wyndham - Columbia
5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Great pool and hot tub. Neat location. Clean room. Amazing A/C. Good parking. Great breakfast. Amazing stay!!!"
A verified traveler stayed at Wingate by Wyndham - Columbia
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