Book Hotels in Prairie Home, MO
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Top Prairie Home hotels

Drury Plaza Hotel Columbia East
3100 Interstate 70 Dr. SE Columbia MO
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $115 total per night from Nov 15 to Nov 16
$115 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"I loved the pool and kick off & Breakfast, wish the pool was open later or earlier and the same with the kick off would like it earlier for a snack then give you more time to enjoy the mixed drinks a little longer but it is a nice touch"
Reviewed on Nov 8, 2026

Wingate by Wyndham - Columbia
3101 Wingate Ct Columbia MO
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $97 total per night from Nov 15 to Nov 16
$97 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
"Clean. Friendly staff. Adequate gym equipment. Would stay here again."
Reviewed on Nov 6, 2026

Isle of Capri Casino Hotel Boonville & Casino - A Caesars Rewards Destination
100 Isle of Capri Blvd Boonville MO
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $99 total per night from Dec 7 to Dec 8
$99 total
Dec 7 - Dec 8
Total with taxes and fees
A casino, 2 restaurants, and a 24-hour gym are all featured at this hotel. Traveling on business? Take advantage of the 3 conference rooms, along with free WiFi ...
"If you’re a non-smoker like I am, whatever you do don’t select the option for room type assigned at check-in. That’s what I picked thinking the difference in room type would refer to the view. Wrong! There’s one floor with smoking rooms, and that’s what I got assigned when I checked in. The place ..."
Reviewed on Nov 8, 2026

Baymont by Wyndham Columbia, MO
2500 I 70 Dr Sw Columbia MO
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $69 total per night from Nov 15 to Nov 16
$69 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...

Stoney Creek Hotel Columbia
2601 S Providence Rd Columbia MO
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $129 total per night from Dec 8 to Dec 9
$129 total
Dec 8 - Dec 9
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling for business? Take advantage of the free WiFi in public areas, laundry service, and conference ...

Country Inn & Suites by Radisson, Columbia, MO
817 N Keene St Columbia MO
Fully refundable
$80 nightly
The price is $90 total per night from Nov 29 to Nov 30
$90 total
Nov 29 - Nov 30
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...

Hotel Blu
3402 Interstate 70 Dr SE Columbia MO
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $69 total per night from Nov 9 to Nov 10
$69 total
Nov 9 - Nov 10
Total with taxes and fees
An indoor pool, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. A grocery/convenience store, a lobby fireplace, ...

Wyndham Executive Center Columbia
2200 I-70 Drive SW Columbia MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $112 total per night from Nov 22 to Nov 23
$112 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

Best Western Plus Columbia Inn
2904 Clark Lane Columbia MO
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $85 total per night from Nov 12 to Nov 13
$85 total
Nov 12 - Nov 13
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Prairie Home hotel reviews by fellow wanderers

Drury Plaza Hotel Columbia East
5 out of 5
Posted 13 hours ago
Travelocity Verified Review
"I loved the pool and kick off & Breakfast, wish the pool was open later or earlier and the same with the kick off would like it earlier for a snack then give you more time to enjoy the mixed drinks a little longer but it is a nice touch"
A verified traveler stayed at Drury Plaza Hotel Columbia East
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