Book Hotels in Prairie Home, MO

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Prairie Home hotels

Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

3 out of 5
3100 Interstate 70 Dr. SE Columbia MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $111 total per night from Jan 11 to Jan 12
$111 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Hands down best hotel I’ve ever stayed in …. Front desk check-in was amazing to the amazing fitness center pool spa room was very clean and they are pet friendly.! They feed you dinner. They feed you breakfast and they hand you three free drink card. Food was amazing. Can’t wait for breakfast in ...

Reviewed on Dec 29, 2025

Opens in a new windowDrury Plaza Hotel Columbia East
Drury Inn & Suites Columbia Stadium Boulevard

Drury Inn & Suites Columbia Stadium Boulevard

3 out of 5
1000 Knipp St Columbia MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Jan 11 to Jan 12
$102 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Room clean. Staff friendly helpful. Got us blanket & xtra pillows.

Reviewed on Dec 31, 2025

Opens in a new windowDrury Inn & Suites Columbia Stadium Boulevard
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

2.5 out of 5
817 N Keene St Columbia MO
Fully refundable
$78 nightly
The price is $88 total per night from Jan 25 to Jan 26
$88 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Need more fruit options and maybe some ceral or oatmeal.

Reviewed on Jan 1, 2026

Opens in a new windowCountry Inn & Suites by Radisson, Columbia, MO
Best Western Plus Columbia Inn

Best Western Plus Columbia Inn

2.5 out of 5
2904 Clark Lane Columbia MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jan 7 to Jan 8
$79 total
Jan 7 - Jan 8
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
.

Reviewed on Jan 1, 2026

Opens in a new windowBest Western Plus Columbia Inn
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

3 out of 5
3101 Wingate Ct Columbia MO
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $92 total per night from Jan 11 to Jan 12
$92 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the express ...
the pool and hot tub was under repair. Our room was very clean and the bed incredibly comfortable. Great pillows. How do I get one of these mattresses? We were there just before Christmas and the lobby was decorated very nice. You could tell they took a lot of time to decorate, which was appreciated. ...

Reviewed on Jan 4, 2026

Opens in a new windowWingate by Wyndham - Columbia
Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

2.5 out of 5
2601 S Providence Rd Columbia MO
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $121 total per night from Jan 18 to Jan 19
$121 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling for business? Take advantage of the free WiFi in public areas, laundry service, and conference ...
It was a fun place. Columbia as a city sucked.

Reviewed on Jan 2, 2026

Opens in a new windowStoney Creek Hotel Columbia
Wyndham Executive Center Columbia

Wyndham Executive Center Columbia

3.5 out of 5
2200 I-70 Drive SW Columbia MO
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $96 total per night from Jan 25 to Jan 26
$96 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Everything was clean and the staff was very on top of it!

Reviewed on Dec 27, 2025

Opens in a new windowWyndham Executive Center Columbia
Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

2.5 out of 5
2500 I 70 Dr Sw Columbia MO
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $64 total per night from Jan 11 to Jan 12
$64 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Room was clean and in good order. The staff was friendly. The breakfast was decent, but the coffee was atrocious.

Reviewed on Dec 29, 2025

Opens in a new windowBaymont by Wyndham Columbia, MO
Ramada by Wyndham Columbia

Ramada by Wyndham Columbia

2.5 out of 5
901 Conley Rd Columbia MO
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $73 total per night from Feb 2 to Feb 3
$73 total
Feb 2 - Feb 3
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Love this little gem in the cut, nice room area is coinvent to local shops. easy access to the highways as well.

Reviewed on Dec 31, 2025

Opens in a new windowRamada by Wyndham Columbia
Don't see what you're looking for?
See all available properties in Prairie Home
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Prairie Home?
Take some of the challenges out of traveling with kids by booking a family-friendly Prairie Home hotel. From special amenities to services that bring a smile, these properties come with perks that'll make your trip smooth sailing: The whole team will enjoy staying at The Shouse. A travel crib and a firepit are just a few of the things that help make this hotel a sought-after option. Also consider Super 8 by Wyndham Boonville. It comes with complimentary breakfast, pet-friendly facilities and lots of opportunities to hang out as a family.
Where can I find cheap hotels in Prairie Home?
At Travelocity you'll find really nice hotels in Prairie Home at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Prairie Home rather than in Prairie Home. We may find you even better rates, too.
How do I find the best Prairie Home hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Prairie Home then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Prairie Home?
The cheapest hotel in Prairie Home is $64. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Prairie Home?
There are 224 hotels in Prairie Home on Travelocity.
What are the best hotels in Prairie Home?
Prairie Home has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Prairie Home for you!
When is the best time to visit Prairie Home?
If you want the joy of a fun-filled trip in peak season, visit Prairie Home during June, August and November. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in Prairie Home?
Based on historic data is usually the cheapest month to visit Prairie Home. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Prairie Home?
There are multiple hotels in Prairie Home that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Prairie Home. We have plenty of kid-friendly hotels in Prairie Home to choose from on Travelocity!
Why book a hotel in Prairie Home through Travelocity?
Because we have the top hotels in Prairie Home! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Prairie Home on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Prairie Home hotel reviews by fellow wanderers

Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

5 out of 5
Posted 1 day ago
Travelocity Verified Review
"the pool and hot tub was under repair. Our room was very clean and the bed incredibly comfortable. Great pillows. How do I get one of these mattresses? We were there just before Christmas and the lobby was decorated very nice. You could tell they took a lot of time to decorate, which was appreciated. The staff was great. Highly recommend and would stay here again. Fair rate as well. "
A verified traveler stayed at Wingate by Wyndham - Columbia
Wingate by Wyndham - Columbia

Explore More Ways to Travel with Travelocity