Book Hotels in Prairie Home, MO
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Top Prairie Home hotels

Drury Plaza Hotel Columbia East
3100 Interstate 70 Dr. SE Columbia MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $111 total per night from Jan 18 to Jan 19
$111 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Great stay, very clean and very nice!
Reviewed on Jan 5, 2026

Drury Inn & Suites Columbia Stadium Boulevard
1000 Knipp St Columbia MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Jan 18 to Jan 19
$102 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Clean as always and the staff is always great!
Reviewed on Jan 5, 2026

Country Inn & Suites by Radisson, Columbia, MO
817 N Keene St Columbia MO
Fully refundable
$78 nightly
The price is $88 total per night from Feb 1 to Feb 2
$88 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Conveniently located property. Room was clean and spacious. Bed was comfortable. Breakfast was awesome. Dining options nearby.
Reviewed on Jan 5, 2026

Best Western Plus Columbia Inn
2904 Clark Lane Columbia MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jan 14 to Jan 15
$79 total
Jan 14 - Jan 15
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
Clean room. Staff was helpful. The toilet was clogged and they fixed it quickly. Breakfast was solid.
Reviewed on Jan 4, 2026

Wingate by Wyndham - Columbia
3101 Wingate Ct Columbia MO
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $92 total per night from Jan 18 to Jan 19
$92 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the express ...
Room and bathroom nice and clean. Bed and pillows fluffy and comfortable. All around a good nights stay at a convenient location.
Reviewed on Jan 9, 2026

Stoney Creek Hotel Columbia
2601 S Providence Rd Columbia MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $111 total per night from Jan 14 to Jan 15
$111 total
Jan 14 - Jan 15
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling for business? Take advantage of the free WiFi in public areas, laundry service, and conference ...
Staff was nice
Reviewed on Jan 5, 2026

Wyndham Executive Center Columbia
2200 I-70 Drive SW Columbia MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Jan 13 to Jan 14
$106 total
Jan 13 - Jan 14
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Everything was great except for the construction going on at the front of the hotel.
Reviewed on Jan 6, 2026

Baymont by Wyndham Columbia, MO
2500 I 70 Dr Sw Columbia MO
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $66 total per night from Jan 18 to Jan 19
$66 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Clean room. Good healthy breakfast options. Safe parking. Friendly staff.
Reviewed on Jan 5, 2026

Ramada by Wyndham Columbia
901 Conley Rd Columbia MO
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $72 total per night from Feb 2 to Feb 3
$72 total
Feb 2 - Feb 3
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
All excellent! Thank you!
Reviewed on Jan 6, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Prairie Home hotel reviews by fellow wanderers

Hampton Inn & Suites Columbia at University
5 out of 5
Posted 5 days ago
Travelocity Verified Review
"Room was excellent, staff was nice!! Bed was hard but everything else was great!!!"
A verified traveler stayed at Hampton Inn & Suites Columbia at University
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