Book Hotels in Pine Island Center, FL
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Top Pine Island Center hotels

Pink Shell Beach Resort and Marina
275 Estero Blvd Fort Myers Beach FL
$271 nightly
The price is $303 total per night from Jun 21 to Jun 22
$303 total
Jun 21 - Jun 22
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 3 restaurants. Enjoy the 3 outdoor pools and free buffet breakfast each morning. Enjoy the ...
"Great place to visit"
Reviewed on Jun 14, 2026

Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
Fully refundableReserve now, pay when you stay
$274 nightly
The price is $303 total per night from Jun 21 to Jun 22
$303 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink ...
"All rooms are clean and quite ,the staff is nice and food is perfect, I recommend it 100%"
Reviewed on Jun 19, 2026

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
1538 Cape Coral Pkwy E Cape Coral FL
Fully refundable
$98 nightly
The price is $109 total per night from Jul 19 to Jul 20
$109 total
Jul 19 - Jul 20
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"It was a business trip and my stay was very comfortable."
Reviewed on Jun 18, 2026

Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
$230 nightly
The price is $257 total per night from Jul 1 to Jul 2
$257 total
Jul 1 - Jul 2
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
"Front desk staff was a great help. Check in/out was swift. Drinks were great and atmosphere was nice."
Reviewed on Jun 18, 2026

Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $160 total per night from Jun 23 to Jun 24
$160 total
Jun 23 - Jun 24
Total with taxes and fees
This smoke-free hotel features 3 restaurants, 3 beach bars, and 6 bars/lounges. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Enjoy ...
"We celebrated our 30th anniversary and we had so much fun Best vacation ever. Staff was so friendly. The beach view 10/10. Rooms were clean."
Reviewed on Jun 19, 2026

Hilton Garden Inn Ft Myers
12600 University Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $106 total per night from Jun 21 to Jun 22
$106 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"Very nice small restaurant/bar area which was convenient after a long day. Beautiful hotel. Kiosk to buy a soda was a bit annoying but they did have drinks and snacks for purchase Room and bed very comfortable"
Reviewed on Jun 19, 2026

Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
$223 nightly
The price is $248 total per night from Jul 2 to Jul 3
$248 total
Jul 2 - Jul 3
Total with taxes and fees
A full-service spa, 4 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy the 5 outdoor tennis courts and indoor pool, and unwind ...
"Beautiful after a major delay and missing our flight the hotel was wonderful and generous since the travel insurance purchased from Expedia did not help one bit I’d highly recommend this resort it was beautiful amazing and so accommodating and luxurious"
Reviewed on Jun 18, 2026

The Lighthouse Resort Inn & Suites
1051 5th St Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$141 nightly
The price is $157 total per night from Jul 5 to Jul 6
$157 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features 2 outdoor pools, a restaurant, and a bar/lounge. Relax with a drink at the poolside bar and enjoy perks like free self parking and free WiFi. ...
"Close to the beach, food was good at the tiki bar. Doing a little remodeling that was really no big deal. Had a room close to the bar. I'm a late night person but if you're not be prepared to hear the music until about 2 a.m. The desk attendant at check-in was awesome. I think his name was Cory or ..."
Reviewed on Jun 17, 2026

Baymont by Wyndham Fort Myers Central
4850 S Cleveland Ave Fort Myers FL
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Jun 21 to Jun 22
$70 total
Jun 21 - Jun 22
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi ...
"Great stay"
Reviewed on Jun 15, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Pine Island Center hotel reviews by fellow wanderers

Sanibel Island Beach Resort
5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"All rooms are clean and quite ,the staff is nice and food is perfect, I recommend it 100%"
A verified traveler stayed at Sanibel Island Beach Resort
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