Deals on vacations and trips to Mississippi County

Save when you book Mississippi County, MO package deals

Choose two or more items and save on your trip:

Mississippi County flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
The Riverview

The Riverview

2 out of 5
per person
Nov 1 - Nov 3
found 19 hours ago
Roundtrip non-stop flight included
El Paso (ELP) to Cape Girardeau (CGI)
This hotel features a casino and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference space. Relax with a drink at one of the 2 bars/lounges and enjoy perks like free self parking.
Rockwood Inn

Rockwood Inn

2 out of 5
per person
Nov 1 - Nov 3
found 19 hours ago
Roundtrip non-stop flight included
El Paso (ELP) to Cape Girardeau (CGI)
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden and a picnic area are also provided.
Super 8 by Wyndham Mayfield

Super 8 by Wyndham Mayfield

2 out of 5
per person
Oct 7 - Oct 12
found 1 day ago
Roundtrip flight included
El Paso (ELP) to Paducah (PAH)
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business center. The front desk is staffed around-the-clock and laundry facilities are on offer.
Wingfield Inn

Wingfield Inn

2 out of 5
per person
Oct 7 - Oct 12
found 1 day ago
Roundtrip flight included
El Paso (ELP) to Paducah (PAH)
This motel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Days Inn by Wyndham Calvert City/Paducah East

Days Inn by Wyndham Calvert City/Paducah East

2 out of 5
per person
Oct 7 - Oct 12
found 1 day ago
Roundtrip flight included
El Paso (ELP) to Paducah (PAH)
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business center and free internet in public areas. There's a seasonal outdoor pool on site, and a 24-hour front desk and a picnic area are also provided.

Top Mississippi County hotels deals

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St, Charleston, MO
Free Cancellation
Reserve now, pay when you stay
$59 nightly
The price is $65 total per night
$65 total
Sep 8 - Sep 9
Total includes taxes and fees
This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. There's a computer station and multilingual staff can provide around-the-clock assistance.
Breakfast included
Pet friendly
Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

2.5 out of 5
102 Drake St, I-57 Exit 10, Charleston, MO
Free Cancellation
Reserve now, pay when you stay
$67 nightly
The price is $75 total per night
$75 total
Sep 8 - Sep 9
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business center and free internet in public areas. A safe deposit box is provided and the front desk is staffed around-the-clock.
Breakfast included
Pet friendly
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
$81 nightly
The price is $92 total per night
$92 total
Aug 24 - Aug 25
Total includes taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour business center, a grocery/convenience store, and express check-out are also on offer.
Pool
Breakfast included
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
$90 nightly
The price is $103 total per night
$103 total
Aug 24 - Aug 25
Total includes taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Breakfast included
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
$66 nightly
The price is $76 total per night
$76 total
Aug 27 - Aug 28
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 3 onsite conference rooms. Enjoy the gym and conveniences like a 24-hour front desk and laundry facilities.
Breakfast included
Pet friendly
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
$80 nightly
The price is $92 total per night
$92 total
Aug 22 - Aug 23
Total includes taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free daily breakfast.
Pool
Hot Tub
Don't see what you're looking for?
See all available properties in Mississippi County
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Photos of local treasures

Browse Mississippi County vacation photos for more inspiration

Frequently asked questions

How much are vacation packages to Mississippi County?
With vacation packages on offer for only $660, it's not necessary to drain your bank balance for your trip to Mississippi County. Travelocity is here to help. Bundle up experiences, hotels and flights into a package and receive some excellent discounts. The more you book, the more you save.
Where can I get the best vacation package deals for Mississippi County?
No matter what you enjoy doing, Travelocity can help you get your hands on the best Mississippi County package deal. The only thing you have to do is select a combination from our 400 airlines and 1,000,000 properties around the world.
Why should I book my Mississippi County vacation bundle with Travelocity?
By booking your hotel, flights, activities and car rental all in one place, you'll save time and money. We have a dedicated team of experts available 24/7, and you'll know that you'll always score the lowest price possible with our Price Match Guarantee. So, what are you waiting for? Book your dream getaway today and get packing!
Can I save money on my Mississippi County car rental if I bundle it with my hotel or flight?
You certainly can with our Mississippi County vacation packages. With one of these, there are plenty of ways to stretch your travel budget further. Bundle any two or more car, hotel, flight and tour bookings and watch your savings pile up. With your own ride, all the main sights around Mississippi County are within your reach.
Which airport is best for Mississippi County?
If you're going to fly into Mississippi County, it's likely you'll be touching down at Cape Girardeau Municipal Airport (CGI) or Barkley Regional Airport (PAH).