Book Hotels in Mayesville, SC
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Top Mayesville hotels

Holiday Inn Express Sumter by IHG
"We usually avoid HI Express, but this Sumpter hotel was in a great location surrounded by lots of restaurants. This was the cleanest hotel, from the lobby to our room to the breakfast area. Our larger room with sofa was spotless, had 2 refrigerators and the beds were very comfortable. Add to this ..."
Reviewed on Aug 15, 2026

SureStay Hotel by Best Western Manning
"Le personnelle etait super bien , dejeuner bien , la chambre etait propre"
Reviewed on Aug 16, 2026

Woodspring Suites Sumter Near Shaw Afb
"Wonderful experience, friendly staff , very clean and smells great"
Reviewed on Aug 17, 2026

Super 8 by Wyndham Sumter
"The room was full of fire ants, and when we called down to the front desk the indian guy cused us out. After one night in the room someone down the sidewalk took a crap on the sidewalk and they never cleaned it up. It sat out in the heat for 2 days. It was disgusting. The orange juice was fake and ..."
Reviewed on Aug 14, 2026

Baymont by Wyndham Manning
"Clean room and great staff"
Reviewed on Aug 16, 2026

Quality Inn Sumter near Shaw AFB
"The first room had some issues but I was given another room that was great! Thanks to the staff for their assistance on that."
Reviewed on Aug 16, 2026

Hyatt Place Sumter / Downtown

Hampton Inn Manning

Comfort Suites Sumter near Shaw AFB
Top reasons for your vacation to Mayesville
- States Museum: Explore the rich history of South Carolina at the States Museum and learn about the local heritage.
- Darlington Raceway: Thrill-seekers must visit the Darlington Raceway to witness exhilarating car racing events.
- Timrod Park: Enjoy a peaceful day surrounded by beautiful scenery and nature trails at Timrod Park.
- Historic Charleston: Take a trip to Historic Charleston to discover its charming architecture and vibrant culture.
- Florence Center: Check out the Florence Center for entertainment and events that cater to all interests.
Find your favorite hotels in Mayesville
If you're planning an outdoor vacation in Mayesville, South Carolina, you'll find a range of hotel accommodations to choose from. Whether you prefer a cozy motel near Turbeville or a top-rated hotel in the area, there are options to suit every budget and preference. Knights Inn Turbeville offers a comfortable stay for those looking for convenience. No matter where you choose to stay, Mayesville and its surrounding areas have plenty to offer for a memorable family vacation.
| Hotel name | Type | Stars | Description |
| Howard Johnson by Wyndham Florence | Motel | 2.0 | This 2.0-star rating motel is conveniently located near the airport and offers connecting rooms, a fitness center, sports facilities, excursions, an outdoor pool, and free breakfast. It also has business amenities and a swimming pool. With its close proximity to Mayesville (28.6 miles), it is a good option for your outdoor vacation. |
| Comfort Inn & Suites | Hotel | 2.5 | This 2.5-star rating hotel is situated close to dining, shopping, family-friendly attractions, cafes, friendly people, business facilities, museums, excursions, entertainment options, and golf courses. It is located 25.2 miles away from Mayesville, making it a convenient choice for your outdoor vacation. |
| La Quinta Inn & Suites by Wyndham Florence | Hotel | 2.5 | With a 2.5-star rating, this hotel offers close proximity to friendly people, pet-friendly policies, connecting rooms, a fitness center, sports facilities, free breakfast, an outdoor pool, and business amenities. It also has a breakfast area and a pool. Located 28.7 miles away from Mayesville, it is a great option for your outdoor vacation. |
Explore the best activities and sights in Mayesville
Mayesville, South Carolina offers a variety of outdoor activities and travel to-dos for a memorable vacation. Explore the rich history of the state at the States Museum and learn about the local heritage. For thrill-seekers, the Darlington Raceway is a must-visit, where you can witness exhilarating car racing events. Enjoy a peaceful day at Timrod Park, surrounded by beautiful scenery and nature trails. Take a trip to Historic Charleston to discover its charming architecture and vibrant culture. Lastly, check out the Florence Center for entertainment and events that cater to all interests.
- Hollywood Beach: Hollywood Beach is a picturesque beach that offers a vibrant and lively atmosphere. With its golden sands and crystal-clear waters, it provides the perfect setting for sunbathing and beach activities. Whether you're into beach sports, dancing, or live music, Hollywood Beach has something for everyone. You can also indulge in delicious dining options at the beachside cafes and explore the nearby shops for unique souvenirs. The captivating entertainment and the gentle sea breeze make Hollywood Beach a must-visit destination for a fun-filled beach experience.
- Myrtle Beach Boardwalk: Myrtle Beach Boardwalk is a charming esplanade that offers a delightful family-friendly experience. Stroll along the boardwalk and enjoy the panoramic views of the beach and the sparkling sea. Witness the breathtaking sunrise and feel the warm sand beneath your feet. The boardwalk is lined with shops, entertainment venues, and dining options, providing ample opportunities for shopping and indulging in delicious seafood. The friendly people and the lively atmosphere make the Myrtle Beach Boardwalk a perfect spot for creating beautiful memories with your loved ones.
- Las Olas Boulevard: Las Olas Boulevard is a vibrant street that offers a diverse range of experiences. Take a leisurely walk along the boulevard and admire the scenic views of the river. The boulevard is adorned with luxurious shops, art galleries, and restaurants, making it a haven for shopping enthusiasts and food lovers. Immerse yourself in the bustling city ambiance and explore the various festivals and events that take place here. Whether you're looking for a taste of fine dining or want to experience the city's cultural scene, Las Olas Boulevard has it all.
Where to stay in Mayesville
Mayesville, South Carolina is a charming destination for an outdoor vacation. Located near Turbeville, the area offers a peaceful and serene atmosphere, perfect for nature lovers. Explore the nearby cities of West Columbia and Turbeville to immerse yourself in the local culture and history. Enjoy outdoor activities such as hiking, fishing, and birdwatching in the beautiful natural surroundings. Mayesville and its surrounding areas provide a joyful escape for families looking to reconnect with nature and create unforgettable memories.
- Florence: Florence, located 29.1 miles away from Mayesville, is a popular city known for its diverse range of attractions. Families can enjoy dining at local restaurants, shopping at unique stores, and exploring family-friendly museums. The city also offers opportunities for excursions and entertainment, with friendly locals and a vibrant atmosphere. Florence is famous for its beautiful gardens, providing a serene environment for outdoor activities. Whether it's strolling through the gardens or enjoying the cafes, Florence offers a blend of cultural experiences and friendly hospitality.
- Sumter: Sumter, just 9.0 miles away from Mayesville, is a city with a strong connection to nature. Families can explore the city's lakes and gardens, immersing themselves in the beauty of the surroundings. Sumter is also known for its vibrant festivals and offers excellent shopping and dining options. Birdwatching enthusiasts will find plenty of opportunities to spot diverse bird species. The city's churches and cathedral add a touch of historical and architectural charm to the atmosphere, making it an ideal destination for families seeking a peaceful and nature-filled vacation.
- Manning: Located 20.2 miles away from Mayesville, Manning is a city that caters to various interests. Families can indulge in dining at local restaurants and enjoy the company of friendly locals. Excursions and recreational activities are readily available, providing opportunities for adventure and relaxation. Manning offers a range of options, from trendy coffee shops to budget-friendly establishments and luxury experiences. Its family-friendly atmosphere ensures that everyone can find something enjoyable. With its proximity to nature and a welcoming atmosphere, Manning is worth visiting for a memorable outdoor vacation with your family.
Mayesville has something in store for you whenever you visit. January is the coldest month of the year, while July is hottest, with average temperatures up to 81.3 degrees Fahrenheit. The wettest month in Mayesville is August, so pack accordingly.
Calendar Month | Temperature | Precipitation | Cloudiness |
| January | 45.9°F (7.7°C) | Light Rain | Mostly Sunny |
| February | 49.8°F (9.9°C) | Light Rain | Mostly Sunny |
| March | 55.8°F (13.2°C) | Light Rain | Mostly Sunny |
| April | 63.7°F (17.6°C) | Light Rain | Mostly Sunny |
| May | 71.4°F (21.9°C) | Light Rain | Mostly Sunny |
| June | 78.4°F (25.8°C) | Light Rain | Mostly Sunny |
| July | 81.3°F (27.4°C) | Light Rain | Mostly Sunny |
| August | 79.7°F (26.5°C) | Light Rain | Mostly Sunny |
| September | 75.0°F (23.9°C) | Light Rain | Mostly Sunny |
| October | 65.3°F (18.5°C) | Light Rain | Mostly Sunny |
| November | 54.9°F (12.7°C) | Light Rain | Mostly Sunny |
| December | 49.8°F (9.9°C) | Light Rain | Mostly Sunny |
How do I find a great hotel with Travelocity?
Give your entire crew a vacation they'll never forget. Explore our extensive collection of family-friendly hotels that offer extra amenities for kids. Use our custom filters to find accommodations near top attractions, with enhanced cleaning protocols and within your budget. Trust our reliable online travel platform to make your search for the perfect accommodations a breeze.
Why should I book with Travelocity?
Conference calls, to-do lists and, of course, football practice. Busy lives and packed schedules call for trips that are stress-free. Our aim is to provide hassle-free travel every time you and your family book with us so that you can spend less time worrying and more time creating wonderful memories. To accomplish this, we will assist you in finding and planning your ideal trip, along with offering transparent pricing and trustworthy reviews, as well as 24/7 guaranteed customer support before, during, and after your vacation.
How can I save money on my trip to Mayesville?
When planning your trip to Mayesville, South Carolina, consider avoiding the peak season from July to September to save money. Bundling your flights, hotel, and car rentals can also help you get a discounted price. This not only saves you money but also makes managing your trip easier. While in Mayesville, explore the beautiful landscapes and attractions with your family. And don't forget to enjoy the local cuisine and hospitality!
Frequently asked questions
Recent Mayesville hotel reviews by fellow wanderers

Woodspring Suites Sumter Near Shaw Afb
"Wonderful experience, friendly staff , very clean and smells great"
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