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Top hotels in Matlacha Isles

Pink Shell Beach Resort and Marina
"The Pink Shell has a great location and is fantastic for families. It has great food and the staff are generally happy to help. But if you're looking for a relaxing, quiet stay then I would recommend elsewhere as the pool music was incredibly loud and if you stay on the 9th floor of the main building ..."
Reviewed on Nov 9, 2026

Sanibel Island Beach Resort
"Lovely stay. Great staff and relaxing environment."
Reviewed on Nov 9, 2026

Hilton Garden Inn Ft Myers
"Excellent location and customer service"
Reviewed on Nov 9, 2026

Lani Kai Beachfront Resort
"Great location to get the full Fort Myers experience. If you’re a light sleeper, this isn’t the place for you. Band plays on ground floor. One elevator takes a little while so be patient. Beds were comfortable. View was amazing! Would stay here again."
Reviewed on Nov 9, 2026

Marriott Sanibel Harbour Resort & Spa
"I just received a $200 charge on my CC post stay for “Resort Fees” which include things I did not use. Additionally, the resort charges $25/day just to park at a place you already paid to stay at. My room was at the Captiva bldg which is not near the main building. The Captiva building does have ..."
Reviewed on Nov 10, 2026

The Lighthouse Resort Inn & Suites
"I have a love hate relationship with this property. The location is great. The pool and bar is amazing. The balcony for my room was spacious and overlooked the pool so that was good, and the parking is secure. Here’s the hate part. The rooms were dank (maybe because it’s so close to the beach and ..."
Reviewed on Nov 9, 2026

Baymont by Wyndham Fort Myers Central
"The person at the front desk was extremely rude for the check in. Bedroom was dirty, but hesite to even say anything because of the way the lady at the front desk was. When to check out and get my $100 deposit at about 7:40 am. And the lady at the front desk told me. I will have to wait until 9am ..."
Reviewed on Nov 10, 2026

Margaritaville Beach Resort Fort Myers

Quality Inn Fort Myers Cape Coral
Matlacha Isles Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Matlacha Isles area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Matlacha Isles to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Matlacha Isles are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Matlacha Isles hotel reviews by fellow wanderers

Lani Kai Beachfront Resort
"Great location to get the full Fort Myers experience. If you’re a light sleeper, this isn’t the place for you. Band plays on ground floor. One elevator takes a little while so be patient. Beds were comfortable. View was amazing! Would stay here again."
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