Find a Hotel in Greater South Side
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Top hotels in Greater South Side
Hotel Fort Des Moines, Curio Collection by Hilton
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $161 total per night from Feb 22 to Feb 23
$161 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. WiFi in public areas is free. Valet parking, a business center, and a coffee shop are also ...
Comfortable beds, clean, the most well dressed and courteous staff. I love the character this hotel has. It’s gorgeous.
Reviewed on Feb 16, 2026
Home2 Suites by Hilton Des Moines at Drake University
2650 University Ave. Des Moines IA
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $100 total per night from Feb 22 to Feb 23
$100 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Stayed overnight at this hotel and it actually exceeded my expectations. The room was clean and the women at the front desk was nice. Will definitely stay again!
Reviewed on Feb 16, 2026
Hampton Inn Des Moines-Airport
5001 Fleur Dr Des Moines IA
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $128 total per night from Mar 1 to Mar 2
$128 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Free perks include continental breakfast, free self parking, and a roundtrip airport shuttle. You'll appreciate ...
Shuttle service was excellent
Reviewed on Feb 11, 2026
Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $74 total per night from Mar 19 to Mar 20
$74 total
Mar 19 - Mar 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
Nice, clean, comfortable and quiet- especially since it’s located at the airport.
Reviewed on Feb 12, 2026
Holiday Inn Des Moines-Airport/Conf Center by IHG
6111 Fleur Dr Des Moines IA
$115 nightly
The price is $129 total per night from Mar 1 to Mar 2
$129 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like free self parking and a free airport shuttle. There's ...
All of the above.
Reviewed on Feb 10, 2026
Sonesta Simply Suites Des Moines
7625 Office Plaza Dr N West Des Moines IA
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $80 total per night from Feb 19 to Feb 20
$80 total
Feb 19 - Feb 20
Total with taxes and fees
A 24-hour gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. A terrace, a snack bar/deli, and a grocery/convenience ...
Very clean Nice staff
Reviewed on Feb 16, 2026
AmericInn by Wyndham Des Moines Airport
1920 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $68 total per night from Feb 23 to Feb 24
$68 total
Feb 23 - Feb 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free self parking, and a free airport shuttle. Traveling on business? Take advantage ...
Room was comfortable.
Reviewed on Feb 10, 2026
Quality Inn & Suites Des Moines Airport
5231 Fleur Dr Des Moines IA
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $72 total per night from Feb 25 to Feb 26
$72 total
Feb 25 - Feb 26
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
Clean hotel. Clean rooms and friendly staff. I booked it the last minute. Checked all my boxes for this hotel.
Reviewed on Feb 17, 2026
Ramada Tropics Resort & Conf Center by Wyndham Des Moines
5000 Merle Hay Rd Urbandale IA
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $79 total per night from Feb 22 to Feb 23
$79 total
Feb 22 - Feb 23
Total with taxes and fees
A water park and a restaurant are featured at this smoke-free hotel. There's fun for all ages with a children's pool and a waterslide, and families will appreciate ...
Had to get a different room because our had not been cleaned. The grandkids had a blast though. Loved playing in the pool area and the arcade.
Reviewed on Feb 8, 2026
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Greater South Side Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Greater South Side area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Greater South Side to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Greater South Side are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Greater South Side hotel reviews by fellow wanderers
Quality Inn & Suites Des Moines Airport
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Clean hotel. Clean rooms and friendly staff. I booked it the last minute. Checked all my boxes for this hotel."
A verified traveler stayed at Quality Inn & Suites Des Moines Airport
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