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Top hotels

82 Acre Hobby Farm with Lincoln Log Cabin

82 Acre Hobby Farm with Lincoln Log Cabin

De Soto
This cabin features a garden, laundry facilities, and barbecue grills.
Comfy and peaceful
"Had a great stay enjoyed the beds, porches and the chickens. Great mornings listening to the birds."

Reviewed on Jun 1, 2025

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82 Acre Hobby Farm with Lincoln Log Cabin
Secluded cabin on private property

Secluded cabin on private property

De Soto
This cabin features a garden, laundry facilities, and barbecue grills.
Seclusion is king.
"If you like seclusion this fits the bill. Nice clean, quite cabin, comfortable beds. We found some really nice quartz crystals on the blue arrow and yellow ribbon trails, and yes we saw the guard turtle a couple of times while walking the trails. Even though we were out in the country, we were still ..."

Reviewed on May 27, 2025

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Secluded cabin on private property
Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold

3 out of 5
3800 State Rt 141, Arnold, MO
Fully refundableReserve now, pay when you stay
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Our stay at the Arnold Srury was excellent! I am always impressed with the quality of dinner and breakfast offerings. The young lady serving drinks was fantastic! We like this Drury more than any of the others."

Reviewed on Jun 11, 2025

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Drury Inn & Suites St. Louis Arnold
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

3.5 out of 5
4800 U.S. Highway 67, De Soto, MO
Fully refundable
This aparthotel's 2 outdoor tennis courts and gym are among the featured amenities. There's fun for all ages with mini golf and a playground, and barbecue grills ...
"I really, really want to love this place. The staff is friendly and helpful and seem like they truly care about making your stay enjoyable. The only problem is that it's run-down a bit. For the money, it's a bargain. The golf course is pretty well kept for a little 5-hole course. It's walkable and ..."

Reviewed on Jun 10, 2025

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Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold

2.5 out of 5
1201 Drury Ln, Arnold, MO
Fully refundableReserve now, pay when you stay
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"The hotel staff was very quick upon check in, even with a line of people. Our room was clean and it was very quiet at night. No issues!"

Reviewed on Jun 8, 2025

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Pear Tree Inn St. Louis Arnold
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

2.5 out of 5
1802 Gamel Cemetery Road, Festus, MO
Fully refundable
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"This place already got high ratings when we booked it. After staying there I can see why. It’s clean, in great condition and the staff are excellent. The breakfast was good too. I recommend it."

Reviewed on Jun 8, 2025

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Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St, Farmington, MO
Fully refundableReserve now, pay when you stay
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"The front desk staff was very kind and helpful in spite of being very busy when I arrived. The atmosphere was nice and the building and my room were clean and neat, nicely furnished with newer carpet. It felt new and updated even though the building is older. The view from my room had some lovely ..."

Reviewed on Jun 12, 2025

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Baymont Inn and Suites by Wyndham Farmington, MO
Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South

2.5 out of 5
1303 Veterans Blvd, Festus, MO
Fully refundableReserve now, pay when you stay
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
"Overall a good place for the night. The not so good: the low flow shower was too low flow (I have long hair and shampooing was a nightmare), 2 small bath towels for 2 adults (really)."

Reviewed on Jun 8, 2025

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Comfort Inn Festus - St Louis South
Lakeside Private Villa | 5-Hole Golf On-Site

Lakeside Private Villa | 5-Hole Golf On-Site

Desoto
A sauna is available at this villa.
Convenient to DeSoto
"The place was clean and we loved the two bedrooms with full bath. The bed is fantastic which was really the purpose Of staying there. I do feel the description is a bit misleading in that the advertisement made it sound like the lake was in view and that it was a stand alone house, not a condo. I ..."

Reviewed on Mar 28, 2023

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Lakeside Private Villa | 5-Hole Golf On-Site
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

De Soto Hotel & Travel Guide\n

Dreaming about exploring De Soto? Travelocity has no hotels and apartments, however, there are 4 places to rest and relax within an easy drive of De Soto.

The nearest Travelocity-listed accommodation is the Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, Missouri, 9 miles (15 kilometers) from the middle of De Soto. Another Travelocity accommodation option is the Lexington Inn - Shalimar Plaza & Conference Center, situated in Missouri, 10 miles (15 kilometers) from the middle of De Soto.

The Comfort Inn is 10 miles (15 kilometers) outside the city center of De Soto. An alternative accommodation option is the Super 8 Pevely, which can be found approximately 14 miles (22 kilometers) away. The Super 8 Potosi Mo as well as the Super 8 Bonne Terre are two other Travelocity-listed accommodation options worth checking out around De Soto.

There are various Travelocity-registered hotels in Pilot Knob, which is situated 35 miles (55 kilometers) south of De Soto. The Fort Davidson Hotel and Shepherd Mountain Inn are a few of the establishments here.

Make sure you get your fix of local sport by making the journey to Busch Stadium, which is 40 miles (64 kilometers) to the northeast of De Soto. Enlightened travelers wanting to find a Travelocity-listed room near to the action can choose from the Four Seasons Hotel St Louis or the Grand Center Inn.

Lambert-St. Louis International Airport is a practical arrival point for flights, and is situated 45 miles (72 kilometers) away from De Soto. Travelocity-listed hotels close to Lambert-St. Louis International Airport include Marriott St. Louis Airport and Holiday Inn St. Louis-Airport.

Frequently asked questions

What are the top kid-friendly hotels in De Soto?
From carefully considered amenities to rooms with bunk beds, kid-friendly hotels are equipped with features that can help transform a nice family vacation into a fantastic one. These De Soto properties make vacationing with your youngsters a snap: Put your bags down at NEW! Traditional Country Home in De Soto w/ Yard!. It comes with a firepit, a fireplace and a flair for making families feel at home. Beautiful 2 bedroom unit at resort, sleeps 6 is also a great choice. After a fun day of exploring, return to your comfy room and perks like a sauna and a king bed.
Where can I find cheap hotels in De Soto?
At Travelocity you’ll find really nice hotels in De Soto at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near De Soto rather than in De Soto. We may find you even better rates, too.
How do I find the best De Soto hotel deals?
Simple! On Travelocity, look through the fantastic offers we’ve already found in De Soto then use our filters to find a great deal that’s perfect for you. Enter your travel dates, select the number of rooms you need, and we’ll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in De Soto?
The cheapest hotel in De Soto is . This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel’s location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in De Soto?
There are 166 hotels in De Soto on Travelocity.
What are the best hotels in De Soto?
De Soto has so many great hotels to choose from at Travelocity — and it’s so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in De Soto for you!
When is the best time to visit De Soto?
If you want the joy of a fun-filled trip in peak season, visit De Soto during March, April and May. If you’d prefer the peace of off-season, book a stay during quieter months, such as June, October and November.
When is the cheapest time to stay in De Soto?
Based on historic data is usually the cheapest month to visit De Soto. However, we have incredible deals all year round, so we’re confident you’ll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in De Soto?
There are multiple hotels in De Soto that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We’ve got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to De Soto. We have plenty of kid-friendly hotels in De Soto to choose from on Travelocity!
Why book a hotel in De Soto through Travelocity?
Because we have the top hotels in De Soto! We want to help you travel more and worry less. That’s why we’ve put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you’re getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in De Soto on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent De Soto hotel reviews by fellow wanderers

Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Our stay at the Arnold Srury was excellent! I am always impressed with the quality of dinner and breakfast offerings. The young lady serving drinks was fantastic! We like this Drury more than any of the others."
A verified traveler stayed at Drury Inn & Suites St. Louis Arnold
Drury Inn & Suites St. Louis Arnold
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