
Deals on vacations and trips to Downtown South San Francisco

Downtown South San Francisco flight + hotel vacation packages
Price found within the past 48 hours. Click for updated prices.

Bay Landing San Francisco Airport Hotel
Bayfront
Price was $723, price is now $360 per person
$360
per person
Feb 6 - Feb 9
found 13 hours ago
Roundtrip flight included
Denver (DEN) to San Francisco (SFO)
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free self parking, and a free airport shuttle. Business travelers can take advantage of the free WiFi in public areas. Enjoy the gym and conveniences like a 24-hour front desk and laundry facilities.

SF Central Hotel
South of Market
Price was $880, price is now $397 per person
$397
per person
Dec 25 - Dec 30
found 15 hours ago
Roundtrip flight included
Denver (DEN) to San Francisco (SFO)
Self parking is available and the hotel's multilingual staff can provide around-the-clock assistance. WiFi in public areas is free. Luggage storage is also provided.

Alpine Inn And Suites
Bayshore Heights
Save 100% on your flight
Price was $854, price is now $467 per person
$467
per person
Jan 18 - Jan 24
found 6 hours ago
Roundtrip flight included
Denver (DEN) to San Francisco (SFO)
This hotel features free WiFi in public areas, laundry facilities, and self parking. Express check-out, luggage storage, and concierge services are also on offer.

HYATT house Belmont/Redwood Shores
Save 100% on your flight
Price was $1,019, price is now $602 per person
$602
per person
Jan 11 - Jan 17
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Francisco (SFO)
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Relax with a drink at the bar/lounge and enjoy the free on-the-go breakfast each morning.

DoubleTree by Hilton San Francisco Airport North Bayfront
Save 100% on your flight
Price was $1,337, price is now $807 per person
$807
per person
Jan 18 - Jan 24
found 6 hours ago
Roundtrip flight included
Denver (DEN) to San Francisco (SFO)
A restaurant and an indoor pool are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Self parking, a snack bar/deli, and express check-out are also offered.
Top Downtown South San Francisco hotels deals

Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$119 nightly
The price is $140 total per night
$140 total
Nov 21 - Nov 22
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a bar/lounge on site, and a 24-hour front desk and laundry facilities are also provided.
Pool
Free WiFi

Hyatt Regency San Francisco
5 Embarcadero Center San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$208 nightly
The price is $245 total per night
$245 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. A coffee shop, a snack bar/deli, and a grocery/convenience store are also on offer.
Pet friendly
Free WiFi

DoubleTree by Hilton Hotel Berkeley Marina
200 Marina Blvd Berkeley CA
Free Cancellation
Reserve now, pay when you stay
$139 nightly
The price is $160 total per night
$160 total
Nov 27 - Nov 28
Total with taxes and fees
A marina, a gym, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. You'll appreciate the indoor pool, bar/lounge, and laundry facilities.
Pool
Hot Tub

Hotel Riu Plaza Fisherman's Wharf
2500 Mason St San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$144 nightly
The price is $170 total per night
$170 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the 24-hour gym and free buffet breakfast each morning.
Pool
Breakfast included

Best Western Plus Grosvenor Airport Hotel
380 S Airport Boulevard South San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$91 nightly
The price is $108 total per night
$108 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Self parking, a library, and express check-in are also offered.
Breakfast included
Free airport shuttle

Fairmont San Francisco
950 Mason Street Atop Nob Hill San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$215 nightly
The price is $253 total per night
$253 total
Nov 23 - Nov 24
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, and valet parking. Relax with a drink at one of the 2 bars/lounges and enjoy the sauna.
Spa
Pet friendly
Don't see what you're looking for?
See all available properties in Downtown South San Francisco
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Golden Gate Bridge
4.5/5(7,244 reviews)
Cars trundle across it and ships sail under it, but the best way to experience this iconic bridge is on foot.

Pier 39
4.5/5(6,817 reviews)
This waterfront attraction offers thrilling rides, innovative street performers and colorful souvenir shops, but it’s the sea lions that win the day.

Moscone Convention Center
4/5(598 reviews)
During your trip, find out what's happening at Moscone Convention Center, a top convention center in San Francisco. Discover the fascinating museums and shops in this vibrant area.
Frequently asked questions
Photos of local treasures
Browse Downtown South San Francisco vacation photos for more inspiration
