Deals on vacations and trips to Downtown South San Francisco
Downtown South San Francisco flight + hotel vacation packages
Price found within the past 48 hours. Click for updated prices.
Bay Landing San Francisco Airport Hotel
Ingold - Milldale
Price was $956, price is now $647 per person
$647
per person
Apr 12 - Apr 17
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to San Francisco (SFO)
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free self parking, and a free airport shuttle. Business travelers can take advantage of the free WiFi in public areas. Enjoy the gym and conveniences like a 24-hour front desk and laundry facilities.
Hotel Riu Plaza Fisherman's Wharf
Fisherman's Wharf
Price was $1,079, price is now $734 per person
$734
per person
Apr 12 - Apr 17
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to San Francisco (SFO)
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the 24-hour gym and free buffet breakfast each morning.
1 Hotel San Francisco
Downtown San Francisco
Save 100% on your flight
Price was $3,137, price is now $2,145 per person
$2,145
per person
Apr 18 - Apr 24
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Francisco (SFO)
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the in-room fitness and perks like free WiFi. There's a bar/lounge on site, and a 24-hour front desk and laundry facilities are also provided.
Huntington Hotel
Downtown San Francisco
Save 100% on your flight
Price was $2,130, price is now $1,461 per person
$1,461
per person
Mar 12 - Mar 16
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
A full-service spa, an indoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. You'll appreciate the gym, bar/lounge, and laundry facilities.
Vinarosa Resort & Spa
Save 100% on your flight
Price was $1,363, price is now $982 per person
$982
per person
Apr 23 - Apr 27
found 1 day ago
Roundtrip non-stop flight included
Minneapolis (MSP) to San Francisco (SFO)
A full-service spa, a 24-hour gym, and a restaurant are all featured at this Tuscan-style hotel. Enjoy the outdoor pool and perks like free WiFi. Enjoy the hot tub and unwind at the bar/lounge and poolside bar.
Top Downtown South San Francisco hotels deals
Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$127 nightly
The price is $149 total per night
$149 total
Feb 16 - Feb 17
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a bar/lounge on site, and a 24-hour front desk and laundry facilities are also provided.
Pool
Free WiFi
Hotel Riu Plaza Fisherman's Wharf
2500 Mason St San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$154 nightly
The price is $181 total per night
$181 total
Feb 10 - Feb 11
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the 24-hour gym and free buffet breakfast each morning.
Pool
Breakfast included
Hilton San Francisco Financial District
750 Kearny St San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$114 nightly
The price is $134 total per night
$134 total
Feb 15 - Feb 16
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and WiFi in public areas. Self parking, a terrace, and limo/town car service are also offered.
Pet friendly
Restaurant
Hyatt Place San Francisco Downtown
701 3rd St San Francisco CA
Free Cancellation
Reserve now, pay when you stay
$179 nightly
The price is $211 total per night
$211 total
Feb 13 - Feb 14
Total with taxes and fees
A bar/lounge and a 24-hour front desk are featured at this hotel, along with self parking. WiFi in public areas is free. A terrace, dry cleaning, and luggage storage are also on offer.
Pet friendly
Free WiFi
Handlery Union Square Hotel
351 Geary St San Francisco CA
$125 nightly
The price is $148 total per night
$148 total
Feb 9 - Feb 10
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a sauna on site, and a 24-hour front desk and express check-out are also provided.
Pool
Pet friendly
Club Quarters Hotel in San Francisco
424 Clay St San Francisco CA
$130 nightly
The price is $153 total per night
$153 total
Feb 16 - Feb 17
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. A coffee shop, a terrace, and limo/town car service are also on offer.
Pet friendly
Free WiFi
Don't see what you're looking for?
See all available properties in Downtown South San Francisco
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Golden Gate Bridge
Cars trundle across it and ships sail under it, but the best way to experience this iconic bridge is on foot.
Pier 39
This waterfront attraction offers thrilling rides, innovative street performers and colorful souvenir shops, but it’s the sea lions that win the day.
Oracle Park
Catch an event at Oracle Park during your trip to San Francisco. Take in the acclaimed art scene and beautiful sunsets in this vibrant area.
Frequently asked questions
Photos of local treasures
Browse Downtown South San Francisco vacation photos for more inspiration
