Deals on vacations and trips to Downtown South San Francisco

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Downtown South San Francisco flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
Marin Suites Hotel
1 Hotel San Francisco
WorldMark San Francisco
Cathedral Hill Hotel
@marbella Lane-oceanfront Retreat w/ Stunning View

Top Downtown South San Francisco hotels deals

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Frequently asked questions

How much are vacation packages to Downtown South San Francisco?
With vacation packages available from just $241, there's no need to empty your piggy bank for your visit to Downtown South San Francisco. Travelocity can help. Combine flights, hotels and experiences into a package and walk away with exciting discounts. The more you book, the bigger the savings.
Where can I get the best vacation package deals for Downtown South San Francisco?
No matter your style, Travelocity can help you get the best Downtown South San Francisco package deal. The only thing you have to do is select a combination from our 400 air carriers and 1,000,000 properties across the globe.
Why should I purchase my Downtown South San Francisco vacation package with Travelocity?
Nothing tops the peace of mind knowing you've just picked up the best price available — that's our Price Match Guarantee. Add to that our enormous range of magical destinations and 24/7 team of customer service professionals and you've got the formula for a hassle-free vacation.
Will I save money on my Downtown South San Francisco car rental if I book it with hotels and flights?
Most definitely — and if you also add a tour or an experience to your Downtown South San Francisco vacation package, you'll pick up even greater savings. With a package from Travelocity, you can find things to do in the region that interest you. Then, jump in your rental car and work your way through the list. Monterey Bay Aquarium is one impressive attraction to take a look at. It's 75 mi from Downtown South San Francisco.

Photos of local treasures

Browse Downtown South San Francisco vacation photos for more inspiration

Photo by Catherine Edejer-McCormick