Explore top 2026 5 Star Hotels in Central United States

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Top Central United States 5 Star hotels

Four Seasons Hotel Chicago

Four Seasons Hotel Chicago

5 out of 5
120 East Delaware Place Chicago IL
Fully refundableReserve now, pay when you stay
$500 nightly
The price is $594 total per night from Nov 22 to Nov 23
$594 total
Nov 22 - Nov 23
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
Opens in a new windowFour Seasons Hotel Chicago
Trump International Hotel & Tower Chicago

Trump International Hotel & Tower Chicago

5 out of 5
401 N Wabash Ave Chicago IL
Fully refundableReserve now, pay when you stay
$461 nightly
The price is $548 total per night from Nov 15 to Nov 16
$548 total
Nov 15 - Nov 16
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly ...
Opens in a new windowTrump International Hotel & Tower Chicago
The Roosevelt New Orleans, A Waldorf Astoria Hotel

The Roosevelt New Orleans, A Waldorf Astoria Hotel

5 out of 5
130 Roosevelt Way New Orleans LA
$238 nightly
The price is $282 total per night from Nov 22 to Nov 23
$282 total
Nov 22 - Nov 23
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.4/10 Exceptional! (1,002 reviews)
"Excellent"

Reviewed on Nov 1, 2026

Opens in a new windowThe Roosevelt New Orleans, A Waldorf Astoria Hotel
Thompson Dallas, by Hyatt

Thompson Dallas, by Hyatt

5 out of 5
205 North Akard Street Dallas TX
Fully refundableReserve now, pay when you stay
$271 nightly
The price is $318 total per night from Nov 26 to Nov 27
$318 total
Nov 26 - Nov 27
Total with taxes and fees
A full-service spa, 3 restaurants, and a hot tub are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public areas, ...
Opens in a new windowThompson Dallas, by Hyatt
The Peninsula Chicago

The Peninsula Chicago

5 out of 5
108 East Superior Street Chicago IL
Fully refundableReserve now, pay when you stay
$625 nightly
The price is $743 total per night from Nov 22 to Nov 23
$743 total
Nov 22 - Nov 23
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities and babysitting. ...
9.8/10 Exceptional! (1,006 reviews)
"Always the best hotel in Chicago!!!!"

Reviewed on Nov 2, 2026

Opens in a new windowThe Peninsula Chicago
The Langham, Chicago

The Langham, Chicago

5 out of 5
330 North Wabash Avenue Chicago IL
Fully refundableReserve now, pay when you stay
$540 nightly
The price is $642 total per night from Nov 22 to Nov 23
$642 total
Nov 22 - Nov 23
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
9.8/10 Exceptional! (1,002 reviews)
"The rooms were very clean and quiet. Also larger than I expected. The bathroom had lang amenities and the location of this property was central to everything in the city."

Reviewed on Nov 2, 2026

Opens in a new windowThe Langham, Chicago
The Windsor Court

The Windsor Court

5 out of 5
300 Gravier St New Orleans LA
$379 nightly
The price is $447 total per night from Nov 29 to Nov 30
$447 total
Nov 29 - Nov 30
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
9.8/10 Exceptional! (1,000 reviews)
"Beautiful hotel, comfy beds and great location. Staff were really friendly and helpful. We had a fantastic stay here and would highly recommend!"

Reviewed on Oct 27, 2026

Opens in a new windowThe Windsor Court
Hotel Crescent Court

Hotel Crescent Court

5 out of 5
400 Crescent Ct Dallas TX
Fully refundableReserve now, pay when you stay
$419 nightly
The price is $491 total per night from Nov 29 to Nov 30
$491 total
Nov 29 - Nov 30
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
Opens in a new windowHotel Crescent Court
The Post Oak Hotel at Uptown Houston

The Post Oak Hotel at Uptown Houston

5 out of 5
1600 West Loop South Houston TX
Fully refundableReserve now, pay when you stay
$513 nightly
The price is $601 total per night from Nov 25 to Nov 26
$601 total
Nov 25 - Nov 26
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
Opens in a new windowThe Post Oak Hotel at Uptown Houston
1 Hotel Nashville

1 Hotel Nashville

5 out of 5
710 Demonbreun St Nashville TN
Fully refundableReserve now, pay when you stay
$277 nightly
The price is $326 total per night from Nov 29 to Nov 30
$326 total
Nov 29 - Nov 30
Total with taxes and fees
A full-service spa, 2 restaurants, and A 24-hour gym are all featured at this smoke-free hotel. Relax with a drink at one of the 2 bars/lounges and get perks ...
9.4/10 Exceptional! (1,004 reviews)
"I can’t say enough about this property and the staff. They made our trip so memorable it was incredible. We go to Nashville often will never not stay here."

Reviewed on Nov 2, 2026

Opens in a new window1 Hotel Nashville
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Central United States Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Central United States to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Central United States 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Central United States before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Central United States hotel reviews by fellow wanderers

Congress Plaza Hotel

Congress Plaza Hotel

5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"Comfortable bed"
A verified traveler stayed at Congress Plaza Hotel
Congress Plaza Hotel