Explore top 2025 5 Star Hotels in Central United States

Name: Four Seasons Hotel Chicago
Price range: $675 total
Rating: 9.4

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Top Central United States 5 Star hotels

Trump International Hotel & Tower Chicago

401 N Wabash Ave, Chicago, IL

Fully refundableReserve now, pay when you stay

$461 nightly

$541 total

Oct 5 - Oct 6

Total with taxes and fees

A full-service spa, an indoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly ...

9.4/10 Exceptional! (1,737 reviews)

"The hotel was above the expectations and river view was fabulous also staff were incredibly awesome specially the front dest employee Natalia she was helpful, smiling and welcoming."

Reviewed on Sep 24, 2025

The Langham, Chicago

330 North Wabash Avenue, Chicago, IL

Fully refundableReserve now, pay when you stay

$544 nightly

$638 total

Oct 26 - Oct 27

Total with taxes and fees

A full-service spa, an indoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...

9.6/10 Exceptional! (1,010 reviews)

"Y"

Reviewed on Sep 21, 2025

The Roosevelt New Orleans, A Waldorf Astoria Hotel

130 Roosevelt Way, New Orleans, LA

Fully refundableReserve now, pay when you stay

$253 nightly

$297 total

Oct 27 - Oct 28

Total with taxes and fees

A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9.2/10 Wonderful! (1,016 reviews)

"The hotel was beautiful and the staff was amazing!"

Reviewed on Sep 25, 2025

1 Hotel Nashville

710 Demonbreun St, Nashville, TN

$359 nightly

$422 total

Oct 19 - Oct 20

Total with taxes and fees

A full-service spa, 2 restaurants, and A 24-hour gym are all featured at this smoke-free hotel. Relax with a drink at one of the 2 bars/lounges and get perks ...

9.2/10 Wonderful! (872 reviews)

"Great service and extremely clean"

Reviewed on Sep 23, 2025

The Peninsula Chicago

108 East Superior Street, Chicago, IL

Fully refundableReserve now, pay when you stay

$595 nightly

$699 total

Oct 26 - Oct 27

Total with taxes and fees

A full-service spa, 2 restaurants, and an indoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities and babysitting. ...

9.6/10 Exceptional! (1,009 reviews)

"The staff is amazing!"

Reviewed on Sep 21, 2025

Conrad Nashville

1620 West End Avenue, Nashville, TN

Fully refundableReserve now, pay when you stay

$343 nightly

$403 total

Oct 5 - Oct 6

Total with taxes and fees

This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Relax with a drink at the bar/lounge and enjoy perks like free WiFi. There's ...

9.6/10 Exceptional! (1,016 reviews)

"Clean and great"

Reviewed on Sep 21, 2025

Rosewood Mansion on Turtle Creek

2821 Turtle Creek Blvd, Dallas, TX

Fully refundableReserve now, pay when you stay

$753 nightly

$884 total

Sep 28 - Sep 29

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free aparthotel. Families will appreciate the onsite laundry facilities and ...

9.2/10 Wonderful! (761 reviews)

"Staff was friendly and accommodating. The property abd rooms are immaculate. We booked a suite and felt at home. A single restaurant on property but the food is amazing!"

Reviewed on Aug 27, 2025

Hotel Crescent Court

400 Crescent Ct, Dallas, TX

$371 nightly

$433 total

Oct 12 - Oct 13

Total with taxes and fees

A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

9.2/10 Wonderful! (1,003 reviews)

"Friendly and helpful staff. Incredibly clean. Amazing facilities."

Reviewed on Sep 10, 2025

The Post Oak Hotel at Uptown Houston

1600 West Loop South, Houston, TX

Fully refundableReserve now, pay when you stay

$523 nightly

$612 total

Oct 12 - Oct 13

Total with taxes and fees

A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9.6/10 Exceptional! (820 reviews)

"Forever my favorite"

Reviewed on Sep 19, 2025

Four Seasons Hotel Chicago

120 East Delaware Place, Chicago, IL

Fully refundableReserve now, pay when you stay

$575 nightly

$675 total

Oct 5 - Oct 6

Total with taxes and fees

A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9.4/10 Exceptional! (1,003 reviews)

"Was very clean, although the toilet wasn’t flushing properly overall a great experience"

Reviewed on Sep 18, 2025

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Central United States Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Central United States to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Central United States 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Central United States before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Central United States hotel reviews by fellow wanderers

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

5 out of 5

Posted 2 days ago

Travelocity Verified Review

"The staff is very friendly and took care of all my requests. The room is very clean, the hotel in general has a good atmosphere. "

A verified traveler stayed at DoubleTree by Hilton Hotel & Suites Houston by the Galleria

Bourbon Orleans Hotel

5 out of 5

Posted 2 days ago

Travelocity Verified Review

"The Bourbon Orleans is a gorgeous boutique hotel steps from everything in the French Quarter. The lobby is a beautiful place to relax, the courtyard pool is tranquil and the rooms are clean and comfortable. Centrally located to everything in the FQ- it was easy to park the car and have a relaxing time strolling the area streets, music venues and shops. There was also a bar with great live music on property . Definitely recommend for a romantic getaway! "

A verified traveler stayed at Bourbon Orleans Hotel