Explore the best 2025 4 Star Hotels Hotels in Central West End
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Top Central West End 4 Star hotels

Hyatt Regency St. Louis at The Arch
315 Chestnut St, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
$109 nightly
The price is $129 total per night
$129 total
Jun 1 - Jun 2
Total includes taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a rooftop terrace on site, and a 24-hour front desk and a coffee shop are also provided.
Pet friendly
Free WiFi

River City Casino & Hotel
777 River City Casino Blvd, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
$129 nightly
The price is $151 total per night
$151 total
Jun 18 - Jun 19
Total includes taxes and fees
This hotel features a casino, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the business center, conference center, and conference space. Enjoy the 24-hour gym and perks like free self parking.
Parking included
Restaurant

Ameristar Casino Resort and Spa
1 Ameristar Blvd, St. Charles, MO
Free Cancellation
Reserve now, pay when you stay
$183 nightly
The price is $214 total per night
$214 total
Jun 1 - Jun 2
Total includes taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside bar.
Pool
Hot Tub

DoubleTree by Hilton St. Louis Airport
4505 Woodson Road, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
$111 nightly
The price is $130 total per night
$130 total
Jun 13 - Jun 14
Total includes taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Bring the family and enjoy the arcade/game room and kid-friendly dining. Unwind with a drink at the bar/lounge and enjoy perks like free self parking and a free airport shuttle.
Pool
Free airport shuttle

Moonrise Hotel
6177 Delmar Blvd, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
$152 nightly
The price is $181 total per night
$181 total
Jun 18 - Jun 19
Total includes taxes and fees
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy a meal from the a restaurant and perks like free self parking.
Pet friendly
Parking included

Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
$127 nightly
The price is $149 total per night
$149 total
Jun 13 - Jun 14
Total includes taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and free airport shuttle. You'll appreciate the seasonal outdoor pool, bar/lounge, and laundry facilities.
Pool
Free airport shuttle

Live by Loews - St.Louis
799 Clark ave, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
$169 nightly
The price is $201 total per night
$201 total
Jun 1 - Jun 2
Total includes taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. There's a rooftop terrace on site, and concierge services and free newspapers are also offered.
Pet friendly
Free WiFi

21C Museum Hotel St Louis
1528 Locust street, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
$165 nightly
The price is $193 total per night
$193 total
Jun 29 - Jun 30
Total includes taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the gym and conveniences like a 24-hour front desk and concierge services.
Pool
Spa

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
$119 nightly
The price is $142 total per night
$142 total
Jun 29 - Jun 30
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. A coffee shop, a snack bar/deli, and a communal living room are also on offer.
Pet friendly
Free WiFi

St. Louis Union Station Hotel, Curio Collection by Hilton
1820 Market Street, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
$191 nightly
The price is $227 total per night
$227 total
Jun 15 - Jun 16
Total includes taxes and fees
This historic hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free WiFi. Valet parking, a business center, and a coffee shop are also offered.
Pool
Pet friendly

Marriott St. Louis Grand
800 Washington Ave, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
$143 nightly
The price is $170 total per night
$170 total
Jun 12 - Jun 13
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Self parking, a coffee shop, and a snack bar/deli are also offered.
Free WiFi
Restaurant

Hilton Pennywell St. Louis at the Arch
400 Olive St, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
$135 nightly
The price is $159 total per night
$159 total
Jun 12 - Jun 13
Total includes taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the express check-in, express check-out, and valet parking. Self parking, dry cleaning, and luggage storage are also offered.
Pet friendly
Restaurant
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See all available properties in Central West End
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Central West End hotels essential information
Accommodation | 1,782 hotels |
---|---|
Lowest Price | $129 |
Highest Price | $227 |
Popular hotels | Hyatt Regency St. Louis at The Arch, River City Casino & Hotel, Ameristar Casino Resort and Spa, DoubleTree by Hilton St. Louis Airport, Moonrise Hotel, Renaissance St. Louis Airport Hotel, Live by Loews - St.Louis, 21C Museum Hotel St Louis , Magnolia Hotel St. Louis, a Tribute Portfolio Hotel, St. Louis Union Station Hotel, Curio Collection by Hilton, Marriott St. Louis Grand, Hilton Pennywell St. Louis at the Arch |
Recent Central West End hotel reviews by fellow wanderers

The West End
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"We were warmly greeted, and felt safe and comfortable the entire stay! Thank you! "
A verified traveler stayed at The West End
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