Book Hotels in Upstate South Carolina, SC
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Top Upstate South Carolina hotels
Hotel Hartness
120 Halston Avenue Greenville SC
Fully refundableReserve now, pay when you stay
The price is $230 total per night from Apr 5 to Apr 6
$230 total
per night
Apr 5 - Apr 6
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and perks like free self parking. ...
Easy
Reviewed on Apr 3, 2026
Grand Bohemian Lodge Greenville, Autograph Collection
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
The price is $316 total per night from Apr 26 to Apr 27
$316 total
per night
Apr 26 - Apr 27
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
The property was excellently maintained!
Reviewed on Apr 2, 2026
Drury Inn & Suites Greenville
10 Carolina Point Pkwy Greenville SC
Fully refundableReserve now, pay when you stay
The price is $131 total per night from Apr 12 to Apr 13
$131 total
per night
Apr 12 - Apr 13
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Everything was awesome i really enjoyed myself
Reviewed on Apr 2, 2026
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
The price is $131 total per night from Apr 5 to Apr 6
$131 total
per night
Apr 5 - Apr 6
A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
This location happy hour is/5
Reviewed on Apr 4, 2026
Hyatt Regency Greenville
220 N Main St Greenville SC
Fully refundableReserve now, pay when you stay
The price is $163 total per night from Apr 12 to Apr 13
$163 total
per night
Apr 12 - Apr 13
This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Property was clean for the most part. Lot of issues with people on the floors partying, but I think it was a special group that was in town for something. Had to call the front desk for security as we couldn’t sleep it almost 1 AM. But the staff was amazing. That’s for sure.
Reviewed on Mar 30, 2026
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
Fully refundable
The price is $111 total per night from Apr 5 to Apr 6
$111 total
per night
Apr 5 - Apr 6
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Spend 2 nights at this hotel was very happy
Reviewed on Apr 3, 2026
Hilton Greenville
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
The price is $109 total per night from Apr 12 to Apr 13
$109 total
per night
Apr 12 - Apr 13
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
Clean room parking was fine
Reviewed on Apr 3, 2026
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
The price is $112 total per night from Apr 12 to Apr 13
$112 total
per night
Apr 12 - Apr 13
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Clean rooms, nice staff, free breakfast
Reviewed on Apr 3, 2026
Hyatt Place Greenville/Haywood
40 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
The price is $100 total per night from Apr 5 to Apr 6
$100 total
per night
Apr 5 - Apr 6
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Old building
Reviewed on Mar 30, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Upstate South Carolina with star-rating
Check Upstate South Carolina Hotels by Star Rating
4 Star Hotels
11 properties
Recent Upstate South Carolina hotel reviews by fellow wanderers
Embassy Suites Greenville Golf Resort & Conference Center
4 out of 5
Posted 1 hour ago
Travelocity Verified Review
"This location happy hour is/5 "
A verified traveler stayed at Embassy Suites Greenville Golf Resort & Conference Center
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