Book Hotels in Upstate South Carolina, SC

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Top Upstate South Carolina hotels

Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3 out of 5
Clemson SC
Free WiFi in public areas is available at this cottage.
Opens in a new windowWooded Cottage - 3 Mi to Clemson University
Homewood Suites by Hilton Greenville Downtown

Homewood Suites by Hilton Greenville Downtown

3 out of 5
950 South Main Street Greenville SC
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $147 total per night from Jan 11 to Jan 12
$147 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Everything was nice and clean. Nice staff and easy parking.

Reviewed on Dec 27, 2025

Opens in a new windowHomewood Suites by Hilton Greenville Downtown
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$235 nightly
The price is $259 total per night from Jan 25 to Jan 26
$259 total
Jan 25 - Jan 26
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...
Awesome place.

Reviewed on Dec 31, 2025

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $108 total per night from Jan 11 to Jan 12
$108 total
Jan 11 - Jan 12
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
El lugar es hermoso y la

Reviewed on Dec 31, 2025

Opens in a new windowEmbassy Suites Greenville Golf Resort & Conference Center
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $84 total per night from Jan 11 to Jan 12
$84 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
The room was clean, staffs were welcoming and the breakfast food was good.

Reviewed on Dec 28, 2025

Opens in a new windowBest Western Plus Greenville I-385 Inn & Suites
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

3 out of 5
11 Ketron Court Greenville SC
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $94 total per night from Jan 5 to Jan 6
$94 total
Jan 5 - Jan 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free breakfast and free WiFi. Traveling on business? Take advantage of the 24-hour business center and ...
size of room, ac was quite, window shades

Reviewed on Dec 30, 2025

Opens in a new windowLa Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St Greenville SC
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $163 total per night from Jan 11 to Jan 12
$163 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Yes

Reviewed on Jan 1, 2026

Opens in a new windowHyatt Regency Greenville
Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $110 total per night from Jan 11 to Jan 12
$110 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
Friendly staff, clean room

Reviewed on Dec 26, 2025

Opens in a new windowHilton Greenville
Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

2.5 out of 5
5009 Pelham Road Greenville SC
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $79 total per night from Jan 3 to Jan 4
$79 total
Jan 3 - Jan 4
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Free perks include full breakfast, free self parking, and a roundtrip airport shuttle. A 24-hour business ...
It was clean nice peaceful and quiet no disturbance rest well great

Reviewed on Dec 24, 2025

Opens in a new windowBest Western Greenville Airport Inn
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