Book Hotels in Upstate South Carolina, SC
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Top Upstate South Carolina hotels
SpringHill Suites by Marriott Greenville Downtown
200 East Washington Street, Greenville, SC
$111 nightly
The price is $122 total per night from Aug 3 to Aug 4
$122 total
Aug 3 - Aug 4
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
"Very modern with beautiful natural elements. 5 min walk to Main St where there is great restaurants and shopping."
Reviewed on Jul 21, 2025
Best Western Plus Greenville I-385 Inn & Suites
831 Congaree Rd, Greenville, SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $93 total per night from Aug 3 to Aug 4
$93 total
Aug 3 - Aug 4
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"good deal"
Reviewed on Jul 24, 2025
Hyatt Regency Greenville
220 N Main St, Greenville, SC
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $172 total per night from Jul 27 to Jul 28
$172 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"It was just OK. Next time we go back to Greenville, we plan to stay somewhere else."
Reviewed on Jul 23, 2025
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd, Greenville, SC
Fully refundable
$99 nightly
The price is $109 total per night from Aug 3 to Aug 4
$109 total
Aug 3 - Aug 4
Total includes taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Finally a hotel with hot water!"
Reviewed on Jul 20, 2025
Woodspring Suites Greenville Airport
205 Entertainment Blvd, Greenville, SC
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $83 total per night from Jul 27 to Jul 28
$83 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Luggage storage and laundry facilities are also provided.
"Smooth check in. Clean room. Fair price. What else matters?"
Reviewed on Jul 23, 2025
Hilton Greenville
45 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $117 total per night from Aug 3 to Aug 4
$117 total
Aug 3 - Aug 4
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
Great place to stay
"We enjoyed our day at the Greenville Hilton. All the staff we encountered was really nice and helpful. The location is so convenient and the price is really reasonable."
Reviewed on Jul 21, 2025
Comfort Inn Greenville - Haywood Mall
246 Congaree Road, Greenville, SC
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $88 total per night from Aug 3 to Aug 4
$88 total
Aug 3 - Aug 4
Total includes taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Front staff girls are very nice"
Reviewed on Jul 23, 2025
La Quinta Inn & Suites by Wyndham Greenville Haywood
65 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $77 total per night from Jul 27 to Jul 28
$77 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. ...
"I book a room that wasn’t available so I had to down size and only received 50$ back as a refund which I’m waiting 5 days to receive it and the deposit."
Reviewed on Jul 23, 2025
Days Inn by Wyndham Anderson
1007 George Smith Mill Rd, Anderson, SC
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $65 total per night from Jul 28 to Jul 29
$65 total
Jul 28 - Jul 29
Total includes taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Good service and great hospitality."
Reviewed on Jul 22, 2025
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Upstate South Carolina with star-rating
Check Upstate South Carolina Hotels by Star Rating
4 Star Hotels
18 properties
Recent Upstate South Carolina hotel reviews by fellow wanderers
Best Western Plus Greenville I-385 Inn & Suites
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"good deal"
A verified traveler stayed at Best Western Plus Greenville I-385 Inn & Suites
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An Attraction
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