Book Hotels in Upstate South Carolina, SC
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Top Upstate South Carolina hotels
Grand Bohemian Lodge Greenville, Autograph Collection
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$287 nightly
The price is $315 total per night from May 25 to May 26
$315 total
May 25 - May 26
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
"Great setting, great service, beautiful rooms and wonderful restaurants"
Reviewed on May 15, 2026
Drury Inn & Suites Greenville
10 Carolina Point Pkwy Greenville SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $130 total per night from May 25 to May 26
$130 total
May 25 - May 26
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Great hotel and staff."
Reviewed on May 19, 2026
Best Western Plus Greenville I-385 Inn & Suites
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $90 total per night from May 31 to Jun 1
$90 total
May 31 - Jun 1
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"ESPRESO MACHINE WAS AWESOME"
Reviewed on May 18, 2026
Hyatt Place Greenville Downtown
128 East Broad Street Greenville SC
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $149 total per night from May 25 to May 26
$149 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"Clean, quiet, nice room"
Reviewed on May 17, 2026
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $121 total per night from May 24 to May 25
$121 total
May 24 - May 25
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"It was definitely a great place to stay"
Reviewed on May 18, 2026
Hyatt Regency Greenville
220 N Main St Greenville SC
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $172 total per night from May 25 to May 26
$172 total
May 25 - May 26
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Nice room, good food places, shopping/walking distance. Nice stay overall."
Reviewed on May 15, 2026
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
Fully refundable
$97 nightly
The price is $107 total per night from May 24 to May 25
$107 total
May 24 - May 25
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Things were like the shuttle drivers were awesome Jimmy, Ella chris and Martha Peyton at the front desk was awesome during the bartender amazing. Very friendly staff the real only problem was is the pool was cold but other than that everything there was great."
Reviewed on May 18, 2026
Hilton Greenville
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $117 total per night from May 25 to May 26
$117 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
"Good food at the hotel restaurant, conveniently located at less than 15 minutes from the Greenville Spartanburg airport. All in all the great quality of Hilton brand!"
Reviewed on May 17, 2026
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $122 total per night from May 24 to May 25
$122 total
May 24 - May 25
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"El baño es muy pequeño, la presión de la ducha es demasiada y el agua sale para el piso."
Reviewed on May 18, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Upstate South Carolina with star-rating
Check Upstate South Carolina Hotels by Star Rating
4 Star Hotels
35 properties
Recent Upstate South Carolina hotel reviews by fellow wanderers
Drury Inn & Suites Greenville
5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Great hotel and staff. "
A verified traveler stayed at Drury Inn & Suites Greenville
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