Find and compare 2 Star hotels in Upstate South Carolina

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Top Upstate South Carolina 2 Star hotels

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Feb 19 to Feb 20
$70 total
Feb 19 - Feb 20
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
7.8/10 Good! (1,001 reviews)
This is a great place to stay and reasonably priced.

Reviewed on Feb 14, 2026

Opens in a new windowDays Inn by Wyndham Anderson
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $76 total per night from Feb 22 to Feb 23
$76 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
9/10 Wonderful! (1,438 reviews)
Yes and yes

Reviewed on Feb 15, 2026

Opens in a new windowBest Western Plus Greenville I-385 Inn & Suites
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $101 total per night from Feb 18 to Feb 19
$101 total
Feb 18 - Feb 19
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8.2/10 Very Good! (1,001 reviews)
Great stay near the university

Reviewed on Feb 11, 2026

Opens in a new windowBest Western Plus Clemson Hotel & Conference Center
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $92 total per night from Feb 24 to Feb 25
$92 total
Feb 24 - Feb 25
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
8/10 Very Good! (676 reviews)
Everting was good

Reviewed on Feb 11, 2026

Opens in a new windowQuality Inn Seneca Clemson Area US-123
ECHO Suites Extended Stay by Wyndham Spartanburg

ECHO Suites Extended Stay by Wyndham Spartanburg

2 out of 5
490 W Blackstock Road Spartanburg SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $93 total per night from Feb 22 to Feb 23
$93 total
Feb 22 - Feb 23
Total with taxes and fees
A 24-hour gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Staff at the 24-hour front desk can provide ...
8/10 Very Good! (343 reviews)
Clean room nice staff

Reviewed on Feb 11, 2026

Opens in a new windowECHO Suites Extended Stay by Wyndham Spartanburg
Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

2 out of 5
1024 Woodruff Rd Greenville SC
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $76 total per night from Mar 8 to Mar 9
$76 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
8.2/10 Very Good! (1,002 reviews)
Recently Renovated room was spotless with new mattress and all new furnishings.

Reviewed on Feb 8, 2026

Opens in a new windowMicrotel Inn & Suites by Wyndham Greenville / Woodruff Rd
Comfort Suites Greenville Airport

Comfort Suites Greenville Airport

2.5 out of 5
1371 Garlington Road Greenville SC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $108 total per night from Mar 15 to Mar 16
$108 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
9.2/10 Wonderful! (1,015 reviews)
Great hotel for traveling pets.... Clean and very poliye staff.

Reviewed on Feb 9, 2026

Opens in a new windowComfort Suites Greenville Airport
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Feb 24 to Feb 25
$109 total
Feb 24 - Feb 25
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
8.2/10 Very Good! (1,000 reviews)
our room was very clean and comfortable. we will stay here again

Reviewed on Feb 4, 2026

Opens in a new windowComfort Inn & Suites Clemson - University Area
Motel 6 Greenville, SC

Motel 6 Greenville, SC

2 out of 5
2015 Wade Hampton Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$50 nightly
The price is $55 total per night from Feb 18 to Feb 19
$55 total
Feb 18 - Feb 19
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. The front desk is staffed around-the-clock and laundry facilities are ...
5.2/10 (778 reviews)
Yes

Reviewed on Feb 8, 2026

Opens in a new windowMotel 6 Greenville, SC
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

2.5 out of 5
246 Congaree Road Greenville SC
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $89 total per night from Mar 1 to Mar 2
$89 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8/10 Very Good! (1,000 reviews)
Good

Reviewed on Feb 10, 2026

Opens in a new windowComfort Inn Greenville - Haywood Mall
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

2 Star Hotels Upstate South Carolina

Looking to break out of your routine for some much needed rest and relaxation? Or maybe you’ve already decided it’s time for a trip and are trying to find affordable hotels in Upstate South Carolina that won’t bust your travel budget?

Upstate South Carolina 2 star hotels will give you everything you need to enjoy the city like a local, saving a ton of money so you can hit all the hot spots in town.

Have a delicious breakfast at your hotel to fuel up for your day of sightseeing, then enjoy amenities like fresh towels and linens, as well as a nice hot shower to unwind after a busy day of experiencing everything the city has to offer.

As you explore a new locale, or one you love to visit over and over, you can rest easy knowing you’re staying in a great hotel that lets you discover Upstate South Carolina and welcomes you back to a clean, comfortable room at night.

Browse Travelocity’s wide selection of 2 star hotels in Upstate South Carolina and find one that’s perfectly priced and places you next to all the best activities and sights. The town is your oyster, and we can help you seek out its secrets while sticking to your budget.

Recent Upstate South Carolina hotel reviews by fellow wanderers

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