Book Hotels in Upstate South Carolina, SC

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Top Upstate South Carolina hotels

Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3 out of 5
Clemson
Free WiFi in public areas is available at this cottage. Take advantage of the free self parking.
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Opens in a new windowWooded Cottage - 3 Mi to Clemson University
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY, Greenville, SC
Fully refundableReserve now, pay when you stay
$267 nightly
The price is $294 total per night from Oct 26 to Oct 27
$294 total
Oct 26 - Oct 27
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...
Parents Weekend
"Beautiful hotel and convenient to everything"

Reviewed on Sep 19, 2025

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
Hyatt Place Greenville Downtown

Hyatt Place Greenville Downtown

3 out of 5
128 East Broad Street, Greenville, SC
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $151 total per night from Oct 5 to Oct 6
$151 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"We parked in the garage across the street at $7 per 24 hours. Extremely reasonable. Super convenient location to Main Street, Falls Park, dining, etc. Left the car parked and walked everywhere."

Reviewed on Sep 22, 2025

Opens in a new windowHyatt Place Greenville Downtown
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd, Greenville, SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $92 total per night from Oct 5 to Oct 6
$92 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Highly recommended Really good value for money"

Reviewed on Sep 24, 2025

Opens in a new windowBest Western Plus Greenville I-385 Inn & Suites
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd, Greenville, SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Oct 19 to Oct 20
$135 total
Oct 19 - Oct 20
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"The bar was not well stocked and I wish they had some kind of alternative to Metal Cans - I understand this is a county wide ordinance and not a hotel specific rule. However it REALLY ruined the ambience and experience of being at a nicer place. If I wanted to have a caned beer I could have gone ..."

Reviewed on Sep 25, 2025

Opens in a new windowEmbassy Suites Greenville Golf Resort & Conference Center
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St, Greenville, SC
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $182 total per night from Oct 12 to Oct 13
$182 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"Nice easy walk to bon seCour center"

Reviewed on Sep 24, 2025

Opens in a new windowHyatt Regency Greenville
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd, Greenville, SC
Fully refundable
$95 nightly
The price is $105 total per night from Oct 5 to Oct 6
$105 total
Oct 5 - Oct 6
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Every thing just needs microwave in the room"

Reviewed on Sep 20, 2025

Opens in a new windowCrowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $114 total per night from Oct 5 to Oct 6
$114 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
Southern Comfort
"Good ol’ southern hospitality. Friendly staff and clean comfortable room. Some minor signs of wear but not enough to diminish comfort. If I ever go back to Greenville I would stay here again."

Reviewed on Sep 21, 2025

Opens in a new windowHilton Greenville
La Quinta Inn & Suites by Wyndham Greenville Haywood

La Quinta Inn & Suites by Wyndham Greenville Haywood

3 out of 5
65 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $77 total per night from Sep 30 to Oct 1
$77 total
Sep 30 - Oct 1
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. ...
"Great VALUE and great room."

Reviewed on Sep 24, 2025

Opens in a new windowLa Quinta Inn & Suites by Wyndham Greenville Haywood
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Upstate South Carolina hotel reviews by fellow wanderers

Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Great location "
A verified traveler stayed at Hyatt Place Greenville/Haywood
Hyatt Place Greenville/Haywood
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