Book Hotels in Upstate South Carolina, SC
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Top Upstate South Carolina hotels
Grand Bohemian Lodge Greenville, Autograph Collection
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$361 nightly
The price is $396 total per night from Aug 31 to Sep 1
$396 total
Aug 31 - Sep 1
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
"Terrific ambiance. Very clean and welcoming!"
Reviewed on Aug 10, 2026
Hyatt Place Greenville Downtown
128 East Broad Street Greenville SC
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $148 total per night from Sep 7 to Sep 8
$148 total
Sep 7 - Sep 8
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"The location was perfect! I had a couple of questions for the staff at the front desk, and they did their best to answer them. Breakfast was clean and each member of our family found something to eat. Again, you can't beat the location!"
Reviewed on Aug 10, 2026
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $111 total per night from Aug 16 to Aug 17
$111 total
Aug 16 - Aug 17
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Great accommodations… always enjoy our stay here!!"
Reviewed on Aug 10, 2026
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $117 total per night from Aug 16 to Aug 17
$117 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Hotel was clean but extremely noisy with baseball teams in residence. The staff made no attempts at controlling the noise. Had a terrible night."
Reviewed on Aug 8, 2026
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
Fully refundable
$97 nightly
The price is $108 total per night from Sep 7 to Sep 8
$108 total
Sep 7 - Sep 8
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Hyatt Regency Greenville
220 N Main St Greenville SC
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $172 total per night from Aug 16 to Aug 17
$172 total
Aug 16 - Aug 17
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Hyatt Place Greenville/Haywood
40 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $91 total per night from Sep 7 to Sep 8
$91 total
Sep 7 - Sep 8
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Best Western Plus Greenville I-385 Inn & Suites
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $105 total per night from Aug 13 to Aug 14
$105 total
Aug 13 - Aug 14
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Hotel Hartness
120 Halston Avenue Greenville SC
Fully refundableReserve now, pay when you stay
$200 nightly
The price is $220 total per night from Aug 16 to Aug 17
$220 total
Aug 16 - Aug 17
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and perks like free self parking. ...
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Upstate South Carolina with star-rating
Check Upstate South Carolina Hotels by Star Rating
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29 properties
Recent Upstate South Carolina hotel reviews by fellow wanderers
Grand Bohemian Lodge Greenville, Autograph Collection
5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"Terrific ambiance. Very clean and welcoming!"
A verified traveler stayed at Grand Bohemian Lodge Greenville, Autograph Collection
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