Explore 118 Luxury Hotels in Northeast Missouri
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Best Luxury Hotels in Northeast Missouri
The Ritz-Carlton, St. Louis
100 Carondelet Plaza St. Louis MO
$549 nightly
The price is $641 total per night from Sep 20 to Sep 21
$641 total
Sep 20 - Sep 21
Total with taxes and fees
This smoke-free hotel's 2 restaurants, 3 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
9.2/10 Wonderful! (586 reviews)
"Don't eat at the restaurant. The food was awful. The service was horrible, maybe worst I've ever had. Couldn't get orders. Couldn't get refills. Server not once asked how the food or drinks were (they were awful as well). And it was an anniversary dinner for us and stay. Hotel pillows were horrible. ..."
Reviewed on Sep 8, 2026
Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $210 total per night from Oct 13 to Oct 14
$210 total
Oct 13 - Oct 14
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and outdoor pool, and unwind with a drink at the poolside ...
8.6/10 Excellent! (1,056 reviews)
"Cancelled my Expedia reservation, despite calling ahead. Painful, as this was an anniversary gift for a family member. Once reservation was restored, all was fine."
Reviewed on Sep 14, 2026
The Westin St. Louis
811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
$136 nightly
The price is $158 total per night from Sep 27 to Sep 28
$158 total
Sep 27 - Sep 28
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.6/10 Excellent! (1,006 reviews)
"The rooms are run down n need a face lift so they look as nice as the rest of the property. We stayed in room 215 n it was run down floor tile changing colors from getting wet I guess, faucets leaked when they r turned on, tiles r cracking all over the bathroom pieces missing under the cabinets, ..."
Reviewed on Sep 14, 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $128 total per night from Sep 20 to Sep 21
$128 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.6/10 Excellent! (1,359 reviews)
"Classic design and architecture."
Reviewed on Sep 14, 2026
Econo Lodge Quincy
224 N 36th Street Quincy IL
Fully refundable
$85 nightly
The price is $97 total per night from Sep 17 to Sep 18
$97 total
Sep 17 - Sep 18
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the express check-in. A grocery/convenience ...
6.8/10 (1,000 reviews)
"Staff was very helpful and understanding."
Reviewed on Sep 7, 2026
Moberly Inn and Suites
1200 Highway 24 East Moberly MO
This luxury hotel features 2 restaurants, a bar/lounge, and an outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public ...
5/10 (172 reviews)
"We did not stay there the motel was condemed The website needs to be took down"
Reviewed on Nov 12, 2018
The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$177 nightly
The price is $209 total per night from Oct 4 to Oct 5
$209 total
Oct 4 - Oct 5
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Oct 4 to Oct 5
$110 total
Oct 4 - Oct 5
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More 4 star hotels in Northeast Missouri
Embassy Suites by Hilton St. Louis Downtown
610 N 7th St St. Louis MO
$114 nightly
The price is $136 total per night from Oct 11 to Oct 12
$136 total
Oct 11 - Oct 12
Total with taxes and fees
9/10 Wonderful! (1,347 reviews)
5 star hotels in Northeast Missouri
The Ritz-Carlton, St. Louis
100 Carondelet Plaza St. Louis MO
$549 nightly
The price is $641 total per night from Sep 20 to Sep 21
$641 total
Sep 20 - Sep 21
Total with taxes and fees
9.2/10 Wonderful! (586 reviews)
Northeast Missouri Luxury Hotels
Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Northeast Missouri luxury hotels are the plush oasis you’ve been looking for.
Choose from the best luxury hotels in Northeast Missouri to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.
We want you to enjoy your next vacation in style and the top luxury resorts in Northeast Missouri will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Northeast Missouri, and plan your next opulent escape.
Northeast Missouri hotels essential information
Accommodation | 3,019 hotels |
|---|---|
Lowest Price | $97 |
Highest Price | $641 |
Popular hotels | The Royal Sonesta Chase Park Plaza St. Louis, Ameristar Casino Resort and Spa, The Ritz-Carlton, St. Louis, Moberly Inn and Suites, Econo Lodge Quincy, Clayton Plaza Hotel & Extended Stay, The Westin St. Louis, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel |
Popular Luxury Stays in Northeast Missouri
Recent Northeast Missouri Hotel Reviews By Fellow Wanderers
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
4 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Breakfast was alright. Room was good. Hot tub was not hot, which was disappointing."
A verified traveler stayed at Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
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