Explore 118 Luxury Hotels in Northeast Missouri
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Best Luxury Hotels in Northeast Missouri
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $123 total per night from Nov 8 to Nov 9
$123 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
8.8/10 Excellent! (3,513 reviews)
"My room looked clean and I'm glad I sprayed everything down because after a while I saw a bed bug on the bed. It stopped where I sprayed lysol on the bed and I sprayed it again and I think it died. I took a picture, got my stuff and left. I payed for the executive suite on my birthday and a bed bug ..."
Reviewed on Nov 2, 2026
The Westin St. Louis
811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $153 total per night from Nov 15 to Nov 16
$153 total
Nov 15 - Nov 16
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.6/10 Excellent! (1,008 reviews)
"Great place to stay if you want to be right down in the middle of all the action! Orlando our valet was amazing!!"
Reviewed on Nov 3, 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $113 total per night from Nov 23 to Nov 24
$113 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.6/10 Excellent! (1,404 reviews)
"It’s a beautiful hotel. Was clean and nicely maintained. Not much in the way of amenities. No vending machines or store to get snacks or drinks. Valet didn’t offer to help with luggage at all, just got the car. No help with luggage, no tip."
Reviewed on Nov 2, 2026
Moberly Inn and Suites
1200 Highway 24 East Moberly MO
This traditional hotel features 2 restaurants, a bar/lounge, and an outdoor pool. Traveling on business? Take advantage of the business center and free WiFi ...
5/10 (172 reviews)
"We did not stay there the motel was condemed The website needs to be took down"
Reviewed on Nov 12, 2018
The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$174 nightly
The price is $205 total per night from Nov 22 to Nov 23
$205 total
Nov 22 - Nov 23
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
$193 nightly
The price is $226 total per night from Nov 16 to Nov 17
$226 total
Nov 16 - Nov 17
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and outdoor pool, and unwind with a drink at the poolside ...
The Ritz-Carlton, St. Louis
100 Carondelet Plaza St. Louis MO
Fully refundableReserve now, pay when you stay
$569 nightly
The price is $664 total per night from Nov 27 to Nov 28
$664 total
Nov 27 - Nov 28
Total with taxes and fees
This smoke-free hotel's 2 restaurants, 3 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
Econo Lodge Quincy
224 N 36th Street Quincy IL
Fully refundable
$76 nightly
The price is $87 total per night from Nov 6 to Nov 7
$87 total
Nov 6 - Nov 7
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the express check-in. A grocery/convenience ...
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More 4 star hotels in Northeast Missouri
Embassy Suites by Hilton St. Louis Downtown
610 N 7th St St. Louis MO
$114 nightly
The price is $135 total per night from Nov 23 to Nov 24
$135 total
Nov 23 - Nov 24
Total with taxes and fees
9/10 Wonderful! (1,369 reviews)
5 star hotels in Northeast Missouri
The Ritz-Carlton, St. Louis
100 Carondelet Plaza St. Louis MO
$569 nightly
The price is $664 total per night from Nov 27 to Nov 28
$664 total
Nov 27 - Nov 28
Total with taxes and fees
Northeast Missouri Luxury Hotels
Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Northeast Missouri luxury hotels are the plush oasis you’ve been looking for.
Choose from the best luxury hotels in Northeast Missouri to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.
We want you to enjoy your next vacation in style and the top luxury resorts in Northeast Missouri will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Northeast Missouri, and plan your next opulent escape.
Northeast Missouri hotels essential information
Accommodation | 3,017 hotels |
|---|---|
Lowest Price | $87 |
Highest Price | $664 |
Popular hotels | The Royal Sonesta Chase Park Plaza St. Louis, Ameristar Casino Resort and Spa, The Ritz-Carlton, St. Louis, Moberly Inn and Suites, Econo Lodge Quincy, Clayton Plaza Hotel & Extended Stay, The Westin St. Louis, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel |
Popular Luxury Stays in Northeast Missouri
Recent Northeast Missouri Hotel Reviews By Fellow Wanderers
Pear Tree Inn St. Louis Airport
4 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Park and Fly was so helpful - and check-in was super fast given how many were in line. Front desk team rocked out 4 in line in less than 10min."
A verified traveler stayed at Pear Tree Inn St. Louis Airport
Clayton Plaza Hotel & Extended Stay
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Whenever we are in St. Louis overnight this is our preferred hotel. Always clean, nice amenities, excellent location and a great breaakfast to get you get you up and going in the morning!"
A verified traveler stayed at Clayton Plaza Hotel & Extended Stay
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