Book a hotel near Mississippi River, United States of America
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Top hotels close to Mississippi River

Hampton Inn St. Charles St. Peters
3720 W Clay St St. Charles MO
Free Cancellation
Reserve now, pay when you stay
61.15 mi from Mississippi River
$95 nightly
The price is $109 total per night
$109 total
Feb 5 - Feb 6
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. A 24-hour business center, free WiFi in public areas, and a picnic area are also on offer.

Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
Free Cancellation
Reserve now, pay when you stay
64.67 mi from Mississippi River
$175 nightly
The price is $205 total per night
$205 total
Jan 11 - Jan 12
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside bar.

Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
Free Cancellation
Reserve now, pay when you stay
65.66 mi from Mississippi River
$142 nightly
The price is $166 total per night
$166 total
Jan 19 - Jan 20
Total with taxes and fees
A casino, 7 restaurants, and a 24-hour gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, and free airport shuttle. Relax with a drink at one of the 3 bars/lounges and enjoy perks like free self parking.

Motel 6 Hazelwood, MO
5781 Campus Ct Hazelwood MO
Free Cancellation
Reserve now, pay when you stay
67.37 mi from Mississippi River
$65 nightly
The price is $79 total per night
$79 total
Jan 11 - Jan 12
Total with taxes and fees
Free self parking is available and the motel's front desk is staffed around-the-clock. WiFi in public areas is free. A snack bar/deli is also provided.

Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
Free Cancellation
Reserve now, pay when you stay
69.84 mi from Mississippi River
$90 nightly
The price is $106 total per night
$106 total
Jan 13 - Jan 14
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Guests will appreciate freebies like buffet breakfast and free self parking.

Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
Free Cancellation
Reserve now, pay when you stay
71.05 mi from Mississippi River
$118 nightly
The price is $138 total per night
$138 total
Jan 23 - Jan 24
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and free airport shuttle. You'll appreciate the seasonal outdoor pool, bar/lounge, and laundry facilities.

Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Free Cancellation
Reserve now, pay when you stay
75.98 mi from Mississippi River
$93 nightly
The price is $109 total per night
$109 total
Jan 24 - Jan 25
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the sauna and free full breakfast each morning.
Pool
Breakfast included

21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
81.27 mi from Mississippi River
$148 nightly
The price is $173 total per night
$173 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the gym and conveniences like a 24-hour front desk and concierge services.

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Free Cancellation
Reserve now, pay when you stay
81.72 mi from Mississippi River
$97 nightly
The price is $115 total per night
$115 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. A coffee shop, a snack bar/deli, and a communal living room are also on offer.

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
333 Washington Ave St. Louis MO
Free Cancellation
Reserve now, pay when you stay
81.9 mi from Mississippi River
$98 nightly
The price is $114 total per night
$114 total
Jan 14 - Jan 15
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the free buffet breakfast each morning.
Pool
Breakfast included

Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Free Cancellation
Reserve now, pay when you stay
82.06 mi from Mississippi River
$125 nightly
The price is $147 total per night
$147 total
Jan 16 - Jan 17
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a rooftop terrace on site, and a 24-hour front desk and a coffee shop are also provided.
Pet friendly
Free WiFi

Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
82.08 mi from Mississippi River
$144 nightly
The price is $168 total per night
$168 total
Jan 13 - Jan 14
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free buffet breakfast each morning.
Don't see what you're looking for?
See all available properties in Mississippi River
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Mississippi River hotels essential information
Accommodation | 15,203 hotels |
|---|---|
Lowest Price | $79 |
Highest Price | $205 |
Popular hotels | Hyatt Regency St. Louis at The Arch, Hampton Inn St. Louis-Downtown (At the Gateway Arch), Clayton Plaza Hotel & Extended Stay, Ameristar Casino Resort and Spa, Renaissance St. Louis Airport Hotel, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel, 21C Museum Hotel St Louis , Pear Tree Inn St. Louis Airport, Hollywood Casino & Hotel St. Louis, Motel 6 Hazelwood, MO, Drury Plaza Hotel St. Louis at the Arch, Hampton Inn St. Charles St. Peters |
Recent Mississippi River hotel reviews by fellow wanderers

Hyatt Regency St. Louis at The Arch
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Room was comfortable and clean!"
A verified traveler stayed at Hyatt Regency St. Louis at The Arch
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