Book a hotel near Mississippi River, United States of America
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Top hotels close to Mississippi River

Comfort Inn & Suites St. Louis - O'Fallon
100 Comfort Inn Ct, O'Fallon, MO
Free Cancellation
Reserve now, pay when you stay
57.58 mi from Mississippi River
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business center and free internet in public areas. Enjoy the indoor pool and conveniences like a 24-hour front desk and laundry facilities.
Pool
Breakfast included

Ameristar Casino Resort and Spa
1 Ameristar Blvd, St. Charles, MO
Free Cancellation
Reserve now, pay when you stay
64.67 mi from Mississippi River
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside bar.
Pool
Hot Tub

Hollywood Casino & Hotel St. Louis
777 Casino Center Drive, Maryland Heights, MO
Free Cancellation
Reserve now, pay when you stay
65.66 mi from Mississippi River
A casino, 7 restaurants, and a 24-hour gym are all featured at this hotel. Traveling for business? Take advantage of the 24-hour business center, express check-out, and conference space. Relax with a drink at one of the 3 bars/lounges and enjoy perks like free self parking.
Parking included
Restaurant

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
13639 Riverport Dr, Maryland Heights, MO
Free Cancellation
Reserve now, pay when you stay
66.26 mi from Mississippi River
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.
Pool
Breakfast included

Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln, St. Ann, MO
Free Cancellation
Reserve now, pay when you stay
69.84 mi from Mississippi River
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included

Wingate by Wyndham St. Louis Airport
10820 Pear Tree Lane, St. Ann, MO
Free Cancellation
Reserve now, pay when you stay
69.85 mi from Mississippi River
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Guests will appreciate freebies like continental breakfast and free self parking.
Pool
Breakfast included

DoubleTree by Hilton St. Louis Airport
4505 Woodson Road, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
70.62 mi from Mississippi River
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Bring the family and enjoy the arcade/game room and kid-friendly dining. Unwind with a drink at the bar/lounge and enjoy perks like free self parking and a free airport shuttle.
Pool
Free airport shuttle

Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
71.05 mi from Mississippi River
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and free airport shuttle. You'll appreciate the seasonal outdoor pool, bar/lounge, and laundry facilities.
Pool
Free airport shuttle

Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
75.98 mi from Mississippi River
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the sauna and free full breakfast each morning.
Pool
Breakfast included

Moonrise Hotel
6177 Delmar Blvd, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
76.8 mi from Mississippi River
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy a meal from the a restaurant and perks like free self parking.
Pet friendly
Parking included

Hyatt Regency St. Louis at The Arch
315 Chestnut St, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
82.06 mi from Mississippi River
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a rooftop terrace on site, and a 24-hour front desk and a coffee shop are also provided.
Pet friendly
Free WiFi

Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
82.08 mi from Mississippi River
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free buffet breakfast each morning.
Pool
Hot Tub
Don't see what you're looking for?
See all available properties in Mississippi River
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Mississippi River hotels essential information
Accommodation | 15,515 hotels |
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Lowest Price | |
Highest Price | |
Popular hotels | Hyatt Regency St. Louis at The Arch, Drury Plaza Hotel St. Louis at the Arch, Pear Tree Inn St. Louis Airport, Hollywood Casino & Hotel St. Louis, Clayton Plaza Hotel & Extended Stay, DoubleTree by Hilton St. Louis Airport, Wingate by Wyndham St. Louis Airport, Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West, Ameristar Casino Resort and Spa, Renaissance St. Louis Airport Hotel, Moonrise Hotel, Comfort Inn & Suites St. Louis - O'Fallon |
Recent Mississippi River hotel reviews by fellow wanderers

Drury Plaza Hotel St. Louis at the Arch
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Great location, loved the kickback and buffets. The hot tub was nice too. "
A verified traveler stayed at Drury Plaza Hotel St. Louis at the Arch
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