Book a hotel near Mississippi River, United States of America
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top hotels close to Mississippi River

Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
Free Cancellation
Reserve now, pay when you stay
64.67 mi from Mississippi River
$157 nightly
The price is $184 total per night
$184 total
Dec 7 - Dec 8
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside bar.
Pool
Hot Tub

Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
Free Cancellation
Reserve now, pay when you stay
65.66 mi from Mississippi River
$89 nightly
The price is $104 total per night
$104 total
Dec 9 - Dec 10
Total with taxes and fees
A casino, 7 restaurants, and a 24-hour gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, and free airport shuttle. Relax with a drink at one of the 3 bars/lounges and enjoy perks like free self parking.
Free airport shuttle
Parking included

Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
Free Cancellation
Reserve now, pay when you stay
69.84 mi from Mississippi River
$90 nightly
The price is $106 total per night
$106 total
Nov 27 - Nov 28
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included

Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
Free Cancellation
Reserve now, pay when you stay
71.05 mi from Mississippi River
$118 nightly
The price is $138 total per night
$138 total
Dec 12 - Dec 13
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and free airport shuttle. You'll appreciate the seasonal outdoor pool, bar/lounge, and laundry facilities.
Pool
Free airport shuttle

Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Free Cancellation
Reserve now, pay when you stay
75.98 mi from Mississippi River
$90 nightly
The price is $105 total per night
$105 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the sauna and free full breakfast each morning.
Pool
Breakfast included

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive Fenton MO
Free Cancellation
Reserve now, pay when you stay
78.62 mi from Mississippi River
$85 nightly
The price is $98 total per night
$98 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Hot Tub

Best Western St. Louis-Kirkwood Route 66
1200 S Kirkwood Road Kirkwood MO
Free Cancellation
Reserve now, pay when you stay
78.96 mi from Mississippi River
$90 nightly
The price is $105 total per night
$105 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and free perks like full breakfast and free self parking.
Pool
Breakfast included

Forest Park Hotel by MDR
5915 Wilson Ave St. Louis MO
Free Cancellation
Reserve now, pay when you stay
79.3 mi from Mississippi River
$93 nightly
The price is $109 total per night
$109 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling for business? Take advantage of the 24-hour business center, express check-out, and conference space. Free parking, a computer station, and luggage storage are also offered.
Pet friendly
Parking included

Pear Tree Inn St. Louis Near Union Station
2211 Market Street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
81 mi from Mississippi River
$94 nightly
The price is $110 total per night
$110 total
Nov 26 - Nov 27
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Hot Tub

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Free Cancellation
Reserve now, pay when you stay
81.72 mi from Mississippi River
$101 nightly
The price is $120 total per night
$120 total
Nov 25 - Nov 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. A coffee shop, a snack bar/deli, and a communal living room are also on offer.
Pet friendly
Free WiFi

Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Free Cancellation
Reserve now, pay when you stay
82.06 mi from Mississippi River
$95 nightly
The price is $111 total per night
$111 total
Nov 24 - Nov 25
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a rooftop terrace on site, and a 24-hour front desk and a coffee shop are also provided.
Pet friendly
Free WiFi

Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
82.08 mi from Mississippi River
$135 nightly
The price is $158 total per night
$158 total
Nov 26 - Nov 27
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free buffet breakfast each morning.
Pool
Hot Tub
Don't see what you're looking for?
See all available properties in Mississippi River
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Mississippi River hotels essential information
Accommodation | 15,088 hotels |
|---|---|
Lowest Price | $98 |
Highest Price | $184 |
Popular hotels | Magnolia Hotel St. Louis, a Tribute Portfolio Hotel, Forest Park Hotel by MDR, Renaissance St. Louis Airport Hotel, Clayton Plaza Hotel & Extended Stay, Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, Pear Tree Inn St. Louis Near Union Station, Hollywood Casino & Hotel St. Louis, Pear Tree Inn St. Louis Airport, Drury Plaza Hotel St. Louis at the Arch, Hyatt Regency St. Louis at The Arch, Ameristar Casino Resort and Spa, Best Western St. Louis-Kirkwood Route 66 |
Recent Mississippi River hotel reviews by fellow wanderers

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"My stay was fantastic! The hotel was easy to locate and the staff was so kind. This was - by far - my favorite hotel property to visit. I had breakfast at Robie’s On 8th the following morning the following morning where I had a quiet breakfast with coffee and Texas toast. The architecture gives offers a lot of reasons to be in awe, and the lounge is a great place to work remotely or relax. I am definitely looking forward to booking a return trip. Thank you! "
A verified traveler stayed at Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
More ways to wander Mississippi River
United States of America Flights
The best fares to get you there
United States of America Hotels
United States of America Vacation Rentals
Great Deals on Alternative Accommodations
United States of America Car Rentals
Affordable cars to get you around town
United States of America Vacations
Save more by combining flights, hotels and cars
Explore More Ways to Travel with Travelocity
- Farmstay in Central United States
- Chalets in Central United States
- Condo Resorts in Central United States
- Condos in Central United States
- Guest Houses in Central United States
- Adults Only Resorts & in Central United States
- All Inclusive Resorts & in Central United States
- Beach Resorts & in Central United States
- Benchmark Hotels in Central United States
- Citizenm Hotels in Central United States
- Drury Inn & Suites Hotels in Central United States
- Four Seasons Hotels in Central United States
- Hilton Hotels in Central United States
- Hotels with Early Check-in in Central United States
- Hotels with Waterslides in Central United States
- Hyatt Hotels in Central United States
- Loews Hotels in Central United States
- Pet Friendly Hotels in Central United States
- Remington Hotels in Central United States
- Ski Resorts and in Central United States
- Sonesta Hotel in Central United States
- Spa Resorts & in Central United States
- Waterpark Hotels and Resorts in Central United States
- Wyndham Hotels in Central United States
- Central United States Hotels
- Vacation Homes in Central United States
- Rv Parks in Central United States
- 5 Star Hotels in Quad Cities
- Apartments in Quad Cities
- B&B in Quad Cities
- Cabins in Quad Cities
- Cottages in Quad Cities
- Extended Stay Hotels in Quad Cities
- Casino Resorts & in Quad Cities
- Cheap Hotels in Quad Cities
- Kid Friendly Hotels in Quad Cities
- Golf Resorts & in Quad Cities
- Hotels with Early Check-in in Quad Cities
- Hotels with Bar in Quad Cities
- Hotels with Hot Tubs in Quad Cities
- Hotels with an Indoor Pool in Quad Cities
- Pet Friendly Hotels in Quad Cities
- Romantic Getaways & Hotels in Quad Cities
- Spa Resorts & in Quad Cities
- Waterpark Hotels and Resorts in Quad Cities
- Quad Cities Hotels
- Houseboats in Quad Cities
- Motels in Quad Cities
- Vacation Homes in Quad Cities
- Rv Parks in Quad Cities
- Apartments in Southeast Iowa
- B&B in Southeast Iowa
- Cabins in Southeast Iowa
- Condos in Southeast Iowa
- Cottages in Southeast Iowa
- Casino Resorts & in Southeast Iowa
- Kid Friendly Hotels in Southeast Iowa
- Hotels with Pools in Southeast Iowa
- Hotels with Bar in Southeast Iowa
- Hotels with Hot Tubs in Southeast Iowa
- Hotels with Waterslides in Southeast Iowa
- Luxury Hotels in Southeast Iowa
- Pet Friendly Hotels in Southeast Iowa
- Romantic Getaways & Hotels in Southeast Iowa
- Waterpark Hotels and Resorts in Southeast Iowa
- Southeast Iowa Hotels
- Lodges in Southeast Iowa
- Motels in Southeast Iowa
- Vacation Homes in Southeast Iowa
- Flights to Central United States
- Flights from Miami to Central United States
- Flights to Quad Cities
- Flights from Brussels to Quad Cities
- Flights from Calgary to Quad Cities
- Flights from Indianapolis to Quad Cities
- Flights from Minneapolis - St. Paul to Quad Cities
- Flights from Nashville to Quad Cities
- Flights from Atlantic City to Quad Cities
- Flights from Lincoln to Quad Cities
- Flights from Boise to Quad Cities
- Flights from Atlanta to Southeast Iowa
- Flights from Chicago to Southeast Iowa
- Flights from Portland to Southeast Iowa
- Flights from Omaha to Southeast Iowa
- Flights from Tulsa to Southeast Iowa
- Car rentals near Central United States
- Car rentals near Quad Cities
- Convertible Car Rentals in Quad Cities
- Luxury Car Rentals in Quad Cities
- Pickup Car Rentals in Quad Cities
- Suv Car Rentals in Quad Cities
- Car rentals near Southeast Iowa
- Minivan Car Rentals in Southeast Iowa
- Pickup Car Rentals in Southeast Iowa





