Book a hotel near Mississippi River, United States of America

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Hotels near Mississippi River

Research Park Inn St Louis West – Chesterfield

32 Research Park Circle, St. Charles, MO, 63304

Free Cancellation

Reserve now, pay when you stay

63.92 mi from Mississippi River

This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 2 conference rooms, as well as the 24-hour business center and free WiFi in public areas. Enjoy the spa tub and free perks like continental breakfast and free self parking.

Ameristar Casino Resort and Spa

1 Ameristar Blvd, St. Charles, MO, 63301

Free Cancellation

Reserve now, pay when you stay

64.67 mi from Mississippi River

This luxury hotel features a casino, a full-service spa, and 5 restaurants. Traveling for business? Take advantage of the free WiFi in public areas, express check-out, and conference center. Make the most of the outdoor pool and indoor pool, and relax with drinks at one of the 2 bars/lounges.

Hollywood Casino & Hotel St. Louis

777 Casino Center Drive, Maryland Heights, MO, 63043

Free Cancellation

Reserve now, pay when you stay

65.66 mi from Mississippi River

This hotel features a casino, a nightclub, and 7 restaurants. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Relax with a drink at one of the 3 bars/lounges and enjoy perks like free self parking.

Elimwood Hotel

13735 Riverport Dr, Maryland Heights, MO, 63043

Free Cancellation

Reserve now, pay when you stay

65.95 mi from Mississippi River

This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 2 conference rooms, as well as the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.

Best Western Plus St. Louis West-Westport

12220 Dorsett Rd, Maryland Heights, MO, 63043

Free Cancellation

Reserve now, pay when you stay

68.96 mi from Mississippi River

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the business center. There's a gym on site, and a 24-hour front desk and express check-out are also provided.

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln, St. Ann, MO, 63074

Free Cancellation

Reserve now, pay when you stay

69.84 mi from Mississippi River

This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Guests will appreciate freebies like buffet breakfast and free self parking.

Best Western Plus St. Louis Airport Hotel

4576 Woodson Road, St. Louis, MO, 63134

Free Cancellation

Reserve now, pay when you stay

70.54 mi from Mississippi River

This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Guests will appreciate freebies like continental breakfast and free self parking.

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue, St. Louis, MO, 63105

Free Cancellation

Reserve now, pay when you stay

75.98 mi from Mississippi River

This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a sauna on site, and laundry facilities and wedding services are also offered.

Moonrise Hotel

6177 Delmar Blvd, St. Louis, MO, 63112

Free Cancellation

Reserve now, pay when you stay

76.8 mi from Mississippi River

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy the a rooftop terrace and perks like free self parking.

Angad Arts Hotel

3550 Samuel Shepard Drive, St. Louis, MO, 63103

Free Cancellation

Reserve now, pay when you stay

79.91 mi from Mississippi River

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the a rooftop terrace and perks like free WiFi. Self parking, a coffee shop, and a terrace are also offered.

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street, St. Louis, MO, 63102

Free Cancellation

Reserve now, pay when you stay

82.08 mi from Mississippi River

This hotel features an indoor pool, a spa tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free buffet breakfast each morning.

Hyatt Regency St. Louis at The Arch

315 Chestnut St, St. Louis, MO, 63102

Free Cancellation

82.09 mi from Mississippi River

This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a rooftop terrace on site, and a 24-hour front desk and a coffee shop are also provided.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels Close to Mississippi River

Your next vacation is around the corner. The kids are out of school, you and the spouse have two weeks off, and it’s about time to get the heck out of dodge. You must experience the culture and see the sights. Book your stay Mississippi River hotels with us at Travelocity and enjoy the trip of a lifetime.

Finally, you can stay near the sites you’ve only read about in books. Now they are next door. Start fresh in the morning with the amazing views from your balcony. Then hop on any number of tour buses and take postcard-worthy pictures of the attractions you once thought couldn’t be real, but now you find them through your lens. Hotels near Mississippi River will offer you the best in prices, activities, amenities, dining, and nightlife.

You may not want to imitate the Griswald’s--that’s been done one too many times—but you do want to have a memorable trip. With Travelocity’s long list of cheap hotels near Mississippi River, you’re sure to find the perfect place to stay within your preferred budget. We’ll match a lower price and refund the difference. Book now and let us make your next vacation the easiest of your life.

Recent Mississippi River hotel reviews by fellow wanderers

Moonrise Hotel
5 out of 5
Posted 18 hours ago
travelocity Verified Review
"The Moonrise was very nice, amazing service at the front desk, clean rooms, great location for food and fun. Also close to the train for traveling to the ball field and back. "
A verified traveler stayed at Moonrise Hotel
Moonrise Hotel
Best Western Plus St. Louis Airport Hotel
5 out of 5
Posted 2 days ago
travelocity Verified Review
"The property was very clean as were the rooms. They were big. The hotel had great shuttle to the airport. The hotel was very convenient."
A verified traveler from Fresno stayed at Best Western Plus St. Louis Airport Hotel
Best Western Plus St. Louis Airport Hotel
Hollywood Casino & Hotel St. Louis
5 out of 5
Posted 2 days ago
travelocity Verified Review
"The hotel was very nice. The beds were great. Hope to be able to come again!"
A verified traveler stayed at Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
Drury Plaza Hotel St. Louis at the Arch
5 out of 5
Posted 2 days ago
travelocity Verified Review
"What I liked about property was how clean room was. The staff was friendly and helpful."
A verified traveler stayed at Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Airport
5 out of 5
Posted 3 days ago
travelocity Verified Review
"This was the first time staying at a Pear Tree Inn and it was a pleasant surprise. Every thing was spic and span. The room was comfortable and spacious. Staff was friendly. The free breakfast and happy hour were very good. The free shuttle to and from the airport was a great service. In the future we will first look for Pear Tree wherever we decide to travel."
A verified traveler stayed at Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Airport
Elimwood Hotel
5 out of 5
Posted 5 days ago
travelocity Verified Review
"This hotel is a best kept secret. The affordability is amazing! With frequent trips to St. Charles, it took me several trips before I gave this hotel a try. I was not disappointed, even with many others to compare! Convenient, comfortable and clean. I really had to look for something to not like about it. A little rust in the tub, a couple cloudy windows, and dry eggs at breakfast. Other than that, great!!! Will definitely be back!"
A verified traveler stayed at Elimwood Hotel
Elimwood Hotel