Book a hotel near Mississippi River, United States of America
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Top hotels close to Mississippi River

Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
Free Cancellation
Reserve now, pay when you stay
65.66 mi from Mississippi River
$162 nightly
The price is $190 total per night
$190 total
Mar 2 - Mar 3
Total with taxes and fees
A casino, 7 restaurants, and a 24-hour gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, and free airport shuttle. Relax with a drink at one of the 3 bars/lounges and enjoy perks like free self parking.
Free airport shuttle
Parking included

Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
Free Cancellation
Reserve now, pay when you stay
69.84 mi from Mississippi River
$87 nightly
The price is $103 total per night
$103 total
Mar 2 - Mar 3
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included

Hilton St. Louis Airport
10330 Natural Bridge Rd St. Louis MO
Free Cancellation
Reserve now, pay when you stay
70.36 mi from Mississippi River
$131 nightly
The price is $156 total per night
$156 total
Feb 28 - Mar 1
Total with taxes and fees
This hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the express check-in, express check-out, and free airport shuttle. A free area shuttle is offered as well.
Free airport shuttle
Pet friendly

Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Free Cancellation
Reserve now, pay when you stay
75.98 mi from Mississippi River
$109 nightly
The price is $127 total per night
$127 total
Feb 27 - Feb 28
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the sauna and free full breakfast each morning.
Pool
Breakfast included

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive Fenton MO
Free Cancellation
Reserve now, pay when you stay
78.62 mi from Mississippi River
$89 nightly
The price is $103 total per night
$103 total
Feb 25 - Feb 26
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Hot Tub

Best Western St. Louis-Kirkwood Route 66
1200 S Kirkwood Road Kirkwood MO
Free Cancellation
Reserve now, pay when you stay
78.97 mi from Mississippi River
$94 nightly
The price is $110 total per night
$110 total
Feb 26 - Feb 27
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free parking, express check-out, and a computer station are also offered.
Pool
Pet friendly

Pear Tree Inn St. Louis Near Union Station
2211 Market Street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
81 mi from Mississippi River
$92 nightly
The price is $108 total per night
$108 total
Mar 2 - Mar 3
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Hot Tub

Drury Inn & Suites St. Louis Union Station
201 S 20th St St. Louis MO
Free Cancellation
Reserve now, pay when you stay
81.21 mi from Mississippi River
$117 nightly
The price is $140 total per night
$140 total
Mar 2 - Mar 3
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free buffet breakfast each morning.
Pool
Hot Tub

21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
81.27 mi from Mississippi River
$131 nightly
The price is $153 total per night
$153 total
Mar 23 - Mar 24
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the gym and conveniences like a 24-hour front desk and concierge services.
Pool
Spa

The Westin St. Louis
811 Spruce St St. Louis MO
81.97 mi from Mississippi River
$127 nightly
The price is $148 total per night
$148 total
Mar 8 - Mar 9
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. Self parking, express check-out, and a computer station are also offered.
Pet friendly
Restaurant

Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Free Cancellation
Reserve now, pay when you stay
82.06 mi from Mississippi River
$149 nightly
The price is $176 total per night
$176 total
Feb 27 - Feb 28
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a rooftop terrace on site, and a 24-hour front desk and a coffee shop are also provided.
Pet friendly
Free WiFi

Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
82.09 mi from Mississippi River
$135 nightly
The price is $158 total per night
$158 total
Mar 1 - Mar 2
Total with taxes and fees
2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy a meal from the restaurant and free buffet breakfast each morning.
Pool
Hot Tub
Don't see what you're looking for?
See all available properties in Mississippi River
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Mississippi River hotels essential information
Accommodation | 15,513 hotels |
|---|---|
Lowest Price | $103 |
Highest Price | $190 |
Popular hotels | Pear Tree Inn St. Louis Airport, Pear Tree Inn St. Louis Near Union Station, Clayton Plaza Hotel & Extended Stay, Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, 21C Museum Hotel St Louis , Hilton St. Louis Airport, The Westin St. Louis, Best Western St. Louis-Kirkwood Route 66, Drury Plaza Hotel St. Louis at the Arch, Hyatt Regency St. Louis at The Arch, Hollywood Casino & Hotel St. Louis, Drury Inn & Suites St. Louis Union Station |
Recent Mississippi River hotel reviews by fellow wanderers

Drury Inn & Suites St. Louis Union Station
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Staff was excellent "
A verified traveler from Sedalia stayed at Drury Inn & Suites St. Louis Union Station
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