Book Hotels in Matlacha Isles-Matlacha Shores, FL
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Top Matlacha Isles-Matlacha Shores hotels

Matlacha on Shoreview
12220-12230 Shoreview Dr Cape Coral FL
$156 nightly
The price is $174 total per night from Mar 29 to Mar 30
$174 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features a picnic area, laundry facilities, and barbecue grills. A virtual front desk are provided for your convenience.
I loved my room ! Everything you could want or need. Beautiful little paradise tucked away in a beautiful, quiet neighborhood !! Host was super helpful and welcoming !! Would stay again in a flash !! Linda A
Reviewed on Feb 27, 2026

Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
Fully refundableReserve now, pay when you stay
$456 nightly
The price is $506 total per night from Mar 5 to Mar 6
$506 total
Mar 5 - Mar 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink ...
The rooms were clean and the bed was comfortable. The pool was nice and well kept. The restaurant on the premises was very good. Enjoyed coffee, shakes and burgers. Only minuses are the front desk staff wasn't very knowledgeable or friendly and the lack of smart TV's is pretty inexcusable in today's ...
Reviewed on Feb 28, 2026

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
1538 Cape Coral Pkwy E Cape Coral FL
Fully refundable
$148 nightly
The price is $165 total per night from Mar 29 to Mar 30
$165 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Very clean room. Keurig in room and coffee in lobby. Comfy beds. Nice exercise area. Great staff. Excellent complimentary breakfast. Had a great but short stay.
Reviewed on Feb 27, 2026

Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
$512 nightly
The price is $571 total per night from Mar 5 to Mar 6
$571 total
Mar 5 - Mar 6
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Relax with a drink at one of the 4 bars/lounges and get perks ...
Room was great , restaurants great,
Reviewed on Feb 26, 2026

Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$320 nightly
The price is $357 total per night from Mar 23 to Mar 24
$357 total
Mar 23 - Mar 24
Total with taxes and fees
This smoke-free hotel features 3 restaurants, 3 beach bars, and 6 bars/lounges. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Enjoy ...
Clean room. Excellent restaurants. Fabulous views.
Reviewed on Feb 28, 2026

Hilton Garden Inn Ft Myers
12600 University Dr Fort Myers FL
$169 nightly
The price is $189 total per night from Mar 29 to Mar 30
$189 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Clean room. Great location. Nice staff
Reviewed on Feb 27, 2026

Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
$470 nightly
The price is $524 total per night from Mar 4 to Mar 5
$524 total
Mar 4 - Mar 5
Total with taxes and fees
A full-service spa, 4 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy the 5 outdoor tennis courts and indoor pool, and unwind ...
The property was nice. I had no idea we would be staying in a separate building away from the main building. The main pool was nice. The staff in the bar area in the evening were amazing. My biggest complaint is that the out side of our building and our room smelled of sewage. We complained to the ...
Reviewed on Feb 27, 2026

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
10150 Daniels Pkwy Fort Myers FL
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $110 total per night from Mar 29 to Mar 30
$110 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Our room had a/c and dehumidifier. It caused me to have allergic reaction as I'm allergic to dust and mold. Not sure which system was the culprit, but there was mold somewhere in the air. Also, walls thin and room next door kept tv on very loud untilb2 am. Breakfast was nice
Reviewed on Feb 27, 2026

Baymont by Wyndham Fort Myers Central
4850 S Cleveland Ave Fort Myers FL
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $103 total per night from Mar 31 to Apr 1
$103 total
Mar 31 - Apr 1
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi ...
I chose this hotel because it was budget-friendly, but unfortunately the experience reflected the price in all the wrong ways. When we checked in, the front desk attendant was not welcoming and gave us very little information. We were simply told to go outside to get to our room, with no real directions. ...
Reviewed on Feb 27, 2026
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Recent Matlacha Isles-Matlacha Shores hotel reviews by fellow wanderers

Lani Kai Beachfront Resort
5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Clean room. Excellent restaurants. Fabulous views. "
A verified traveler from Scarborough stayed at Lani Kai Beachfront Resort
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