Book Hotels in Matlacha Isles-Matlacha Shores, FL

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Top Matlacha Isles-Matlacha Shores hotels

Matlacha on Shoreview

Matlacha on Shoreview

2 out of 5
12220-12230 Shoreview Dr Cape Coral FL
$115 nightly
The price is $128 total per night from Jan 19 to Jan 20
$128 total
Jan 19 - Jan 20
Total with taxes and fees
This hotel features a picnic area, laundry facilities, and barbecue grills. A virtual front desk are provided for your convenience.
Everything was just perfect.

Reviewed on Jan 9, 2026

Opens in a new windowMatlacha on Shoreview
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2.5 out of 5
1538 Cape Coral Pkwy E Cape Coral FL
Fully refundable
$170 nightly
The price is $190 total per night from Jan 18 to Jan 19
$190 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Privacy with own balcony, great breakfast every morning and friendly stuff.

Reviewed on Jan 6, 2026

Opens in a new windowHoliday Inn Express Cape Coral-Fort Myers Area by IHG
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$188 nightly
The price is $210 total per night from Jan 21 to Jan 22
$210 total
Jan 21 - Jan 22
Total with taxes and fees
This smoke-free hotel features 3 restaurants, 3 beach bars, and 6 bars/lounges. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Enjoy ...
This was our first time staying at the Lani Kai. Thoroughly enjoyed our stay. Property is a stunning postcard for a beach resort. Easy, friendly check in. Clean room with incredible view, nicely heated pool, and large selection of dining options to suit anyone’s taste. Took great pride in keeping ...

Reviewed on Jan 10, 2026

Opens in a new windowLani Kai Beachfront Resort
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
Fully refundableReserve now, pay when you stay
$268 nightly
The price is $296 total per night from Jan 25 to Jan 26
$296 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink ...
The cafe had a fish smell when you first walk in, other than that everything was excellent

Reviewed on Jan 8, 2026

Opens in a new windowSanibel Island Beach Resort
DiamondHead Beach Resort

DiamondHead Beach Resort

3.5 out of 5
2000 Estero Blvd Fort Myers Beach FL
$334 nightly
The price is $372 total per night from Jan 15 to Jan 16
$372 total
Jan 15 - Jan 16
Total with taxes and fees
This smoke-free resort features 2 hot tubs, an outdoor pool, and a restaurant. Dine at the beachfront restaurant and relax with beach umbrellas. Enjoy the gym ...
we like our stay

Reviewed on Jan 11, 2026

Opens in a new windowDiamondHead Beach Resort
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
$294 nightly
The price is $328 total per night from Jan 20 to Jan 21
$328 total
Jan 20 - Jan 21
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Relax with a drink at one of the 4 bars/lounges and get perks ...
Will be back.

Reviewed on Jan 7, 2026

Opens in a new windowMargaritaville Beach Resort Fort Myers
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

3 out of 5
12600 University Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
$164 nightly
The price is $183 total per night from Jan 25 to Jan 26
$183 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
The staff at the counter are not friendly at all, the room was just clean.

Reviewed on Jan 6, 2026

Opens in a new windowHilton Garden Inn Ft Myers
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
$396 nightly
The price is $442 total per night from Jan 15 to Jan 16
$442 total
Jan 15 - Jan 16
Total with taxes and fees
A full-service spa, 4 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy the 5 outdoor tennis courts and indoor pool, and unwind ...
Staff was very nice. A problem we had was their were 4 of us in the room and trying to get 4 towels and washcloths was a hard task, also coffee in room.

Reviewed on Jan 3, 2026

Opens in a new windowMarriott Sanibel Harbour Resort & Spa
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $90 total per night from Jan 16 to Jan 17
$90 total
Jan 16 - Jan 17
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi ...
Nice place

Reviewed on Jan 9, 2026

Opens in a new windowBaymont by Wyndham Fort Myers Central
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Matlacha Isles-Matlacha Shores?
From well-thought-out amenities to rooms with bunk beds, kid-friendly hotels come with features that can help transform a regular family vacation into an amazing one. These Matlacha Isles-Matlacha Shores properties make traveling with your youngsters a piece of cake: Unpack your bags at Island Paradise 4 - Full furnishings w/ pool & beach!. It comes with a swimming pool, a playground and a talent for making families feel at home. 8 Person 2-Bedroom Condo with Waterview Balcony - Tarpon - Welcome to our stunning two-bedroom condo room with a balcony! is another top pick. After an exciting day of sightseeing, return to your comfy room and amenities like a swimming pool and pet-friendly facilities.
Where can I find cheap hotels in Matlacha Isles-Matlacha Shores?
At Travelocity you'll find really nice hotels in Matlacha Isles-Matlacha Shores at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Matlacha Isles-Matlacha Shores rather than in Matlacha Isles-Matlacha Shores. We may find you even better rates, too.
How do I find the best Matlacha Isles-Matlacha Shores hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Matlacha Isles-Matlacha Shores then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Matlacha Isles-Matlacha Shores?
The cheapest hotel in Matlacha Isles-Matlacha Shores is $90. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Matlacha Isles-Matlacha Shores?
There are 14,578 hotels in Matlacha Isles-Matlacha Shores on Travelocity.
What are the best hotels in Matlacha Isles-Matlacha Shores?
Matlacha Isles-Matlacha Shores has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Matlacha Isles-Matlacha Shores for you!
When is the best time to visit Matlacha Isles-Matlacha Shores?
If you want the joy of a fun-filled trip in peak season, visit Matlacha Isles-Matlacha Shores during December, January and February. If you'd prefer the peace of off-season, book a stay during quieter months, such as May, September and October.
When is the cheapest time to stay in Matlacha Isles-Matlacha Shores?
Based on historic data is usually the cheapest month to visit Matlacha Isles-Matlacha Shores. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Matlacha Isles-Matlacha Shores?
There are multiple hotels in Matlacha Isles-Matlacha Shores that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Matlacha Isles-Matlacha Shores. We have plenty of kid-friendly hotels in Matlacha Isles-Matlacha Shores to choose from on Travelocity!
Why book a hotel in Matlacha Isles-Matlacha Shores through Travelocity?
Because we have the top hotels in Matlacha Isles-Matlacha Shores! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Matlacha Isles-Matlacha Shores on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Matlacha Isles-Matlacha Shores hotel reviews by fellow wanderers

DiamondHead Beach Resort

DiamondHead Beach Resort

5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Pool was perfect temperature. Plenty of umbrella for shade "
A verified traveler stayed at DiamondHead Beach Resort
DiamondHead Beach Resort

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