Book Hotels in Matlacha Isles-Matlacha Shores, FL

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Nov 6 - Nov 8
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Top Matlacha Isles-Matlacha Shores hotels

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2.5 out of 5
1538 Cape Coral Pkwy E Cape Coral FL
Fully refundable
$100 nightly
The price is $112 total per night from Nov 3 to Nov 4
$112 total
Nov 3 - Nov 4
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Habitación buena y limpia"

Reviewed on Oct 31, 2026

Opens in a new windowHoliday Inn Express Cape Coral-Fort Myers Area by IHG
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
Fully refundableReserve now, pay when you stay
$224 nightly
The price is $250 total per night from Nov 1 to Nov 2
$250 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink ...
"I really enjoyed my stay there. The only disappointment is that there are no tennis courts. When I asked the front desk, they said that there haven't had any since the hurricane a few years ago. Expedia needs to clarify this."

Reviewed on Oct 31, 2026

Opens in a new windowSanibel Island Beach Resort
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$210 nightly
The price is $234 total per night from Nov 1 to Nov 2
$234 total
Nov 1 - Nov 2
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
"So awesome. Love it here."

Reviewed on Oct 31, 2026

Opens in a new windowMargaritaville Beach Resort Fort Myers
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

3 out of 5
12600 University Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $113 total per night from Nov 8 to Nov 9
$113 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"Nice place"

Reviewed on Oct 30, 2026

Opens in a new windowHilton Garden Inn Ft Myers
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $149 total per night from Nov 2 to Nov 3
$149 total
Nov 2 - Nov 3
Total with taxes and fees
This smoke-free hotel features 3 restaurants, 3 beach bars, and 6 bars/lounges. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Enjoy ...
"We loved our stay. Plenty of food and drink options. Room was clean"

Reviewed on Oct 31, 2026

Opens in a new windowLani Kai Beachfront Resort
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
$239 nightly
The price is $266 total per night from Nov 15 to Nov 16
$266 total
Nov 15 - Nov 16
Total with taxes and fees
A full-service spa, 4 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy the 5 outdoor tennis courts and indoor pool, and unwind ...
"Beautiful resort. The fitness center was well equipped and clean. The pools were wonderful. Dolphins were observed feeding just off the dock. The walking paths are nice. Even off season there were plenty of staff in restaurant and at the pool cafe. Great view off the balcony of our room. Be prepared ..."

Reviewed on Oct 30, 2026

Opens in a new windowMarriott Sanibel Harbour Resort & Spa
The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

3 out of 5
1051 5th St Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $164 total per night from Nov 2 to Nov 3
$164 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features 2 outdoor pools, a restaurant, and a bar/lounge. Relax with a drink at the poolside bar and enjoy perks like free self parking and free WiFi. ...
"Nice staff"

Reviewed on Oct 31, 2026

Opens in a new windowThe Lighthouse Resort Inn & Suites
Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral

2 out of 5
4760 S Cleveland Ave Fort Myers FL
Fully refundable
$52 nightly
The price is $57 total per night from Nov 22 to Nov 23
$57 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the laundry ...
"Clean outdated rooms. Wasn't impressed with breakfast bar."

Reviewed on Oct 30, 2026

Opens in a new windowQuality Inn Fort Myers Cape Coral
Matlacha on Shoreview

Matlacha on Shoreview

2 out of 5
12220-12230 Shoreview Dr Cape Coral FL
$120 nightly
The price is $134 total per night from Nov 1 to Nov 2
$134 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features a picnic area, laundry facilities, and barbecue grills. A virtual front desk are provided for your convenience.
Opens in a new windowMatlacha on Shoreview
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Matlacha Isles-Matlacha Shores?
From well-thought-out amenities to rooms with bunk beds, kid-friendly hotels come with features that can help transform a regular family vacation into an amazing one. These Matlacha Isles-Matlacha Shores properties make traveling with your youngsters a piece of cake: Unpack your bags at Island Paradise 4 - Full furnishings w/ pool & beach!. It comes with a swimming pool, a playground and a talent for making families feel at home. 8 Person 2-Bedroom Condo with Waterview Balcony - Tarpon - Welcome to our stunning two-bedroom condo room with a balcony! is another top pick. After an exciting day of sightseeing, return to your comfy room and amenities like a swimming pool and pet-friendly facilities.
Where can I find cheap hotels in Matlacha Isles-Matlacha Shores?
At Travelocity you'll find really nice hotels in Matlacha Isles-Matlacha Shores at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Matlacha Isles-Matlacha Shores rather than in Matlacha Isles-Matlacha Shores. We may find you even better rates, too.
How do I find the best Matlacha Isles-Matlacha Shores hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Matlacha Isles-Matlacha Shores then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Matlacha Isles-Matlacha Shores?
The cheapest hotel in Matlacha Isles-Matlacha Shores is $57. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Matlacha Isles-Matlacha Shores?
There are 15,159 hotels in Matlacha Isles-Matlacha Shores on Travelocity.
What are the best hotels in Matlacha Isles-Matlacha Shores?
Matlacha Isles-Matlacha Shores has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Matlacha Isles-Matlacha Shores for you!
When is the best time to visit Matlacha Isles-Matlacha Shores?
If you want the joy of a fun-filled trip in peak season, visit Matlacha Isles-Matlacha Shores during December, January and February. If you'd prefer the peace of off-season, book a stay during quieter months, such as May, September and October.
When is the cheapest time to stay in Matlacha Isles-Matlacha Shores?
Based on historic data is usually the cheapest month to visit Matlacha Isles-Matlacha Shores. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Matlacha Isles-Matlacha Shores?
There are multiple hotels in Matlacha Isles-Matlacha Shores that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Matlacha Isles-Matlacha Shores. We have plenty of kid-friendly hotels in Matlacha Isles-Matlacha Shores to choose from on Travelocity!
Why book a hotel in Matlacha Isles-Matlacha Shores through Travelocity?
Because we have the top hotels in Matlacha Isles-Matlacha Shores! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Matlacha Isles-Matlacha Shores on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Matlacha Isles-Matlacha Shores hotel reviews by fellow wanderers

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"Habitación buena y limpia"
A verified traveler stayed at Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

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