Book a hotel near Main Street Cultural District, Ames

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Top hotels close to Main Street Cultural District

Comfort Inn and Suites Ames near ISU Campus

Comfort Inn and Suites Ames near ISU Campus

2.5 out of 5
603 South 16th Street, Ames, IA
Free Cancellation
Reserve now, pay when you stay
1.13 mi from Main Street Cultural District
$86 nightly
The price is $97 total per night
$97 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like full breakfast and free self parking.
GrandStay Hotel & Suites

GrandStay Hotel & Suites

2.5 out of 5
1606 S Kellogg Ave, Ames, IA
Free Cancellation
Reserve now, pay when you stay
1.22 mi from Main Street Cultural District
$109 nightly
The price is $122 total per night
$122 total
Nov 17 - Nov 18
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.
SpringHill Suites by Marriott Ames

SpringHill Suites by Marriott Ames

2.5 out of 5
1810 SE 16TH STREET, Ames, IA
Free Cancellation
Reserve now, pay when you stay
1.78 mi from Main Street Cultural District
$93 nightly
The price is $104 total per night
$104 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of the laundry service. Enjoy the indoor pool and conveniences like a 24-hour front desk and laundry facilities.
Microtel Inn & Suites by Wyndham Ames

Microtel Inn & Suites by Wyndham Ames

2 out of 5
2216 Se 16th St, Ames, IA
Free Cancellation
Reserve now, pay when you stay
2.04 mi from Main Street Cultural District
$67 nightly
The price is $75 total per night
$75 total
Nov 17 - Nov 18
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour business center. Enjoy the 24-hour gym and conveniences like a 24-hour front desk and laundry facilities.
Best Western Plus University Park Inn & Suites

Best Western Plus University Park Inn & Suites

2.5 out of 5
2500 University Blvd., Ames, IA
Free Cancellation
Reserve now, pay when you stay
2.05 mi from Main Street Cultural District
$82 nightly
The price is $92 total per night
$92 total
Dec 1 - Dec 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and free perks like continental breakfast and free self parking.
Gateway Hotel and Conference Center at Iowa State University

Gateway Hotel and Conference Center at Iowa State University

3 out of 5
2100 Green Hills Drive, Ames, IA
2.1 mi from Main Street Cultural District
$94 nightly
The price is $106 total per night
$106 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference space. Enjoy the gym and perks like free self parking.
Pool
Hot Tub
Country Inn & Suites by Radisson, Ames, IA

Country Inn & Suites by Radisson, Ames, IA

2.5 out of 5
2605 Se 16th St, Ames, IA
Free Cancellation
2.15 mi from Main Street Cultural District
$84 nightly
The price is $94 total per night
$94 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and free perks like continental breakfast and free self parking.
Pool
Hot Tub
Hilton Garden Inn Ames

Hilton Garden Inn Ames

3 out of 5
1325 Dickinson Ave, Ames, IA
Free Cancellation
Reserve now, pay when you stay
3.47 mi from Main Street Cultural District
$99 nightly
The price is $111 total per night
$111 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the gym and perks like free self parking and free WiFi. A 24-hour business center, a terrace, and a garden are also on offer.
Pool
Pet friendly
Qube Hotel

Qube Hotel

2.5 out of 5
300 Boulder Pointe, Polk City, IA
Free Cancellation
Reserve now, pay when you stay
17.91 mi from Main Street Cultural District
$85 nightly
The price is $95 total per night
$95 total
Nov 12 - Nov 13
Total with taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. A business center, a terrace, and a garden are also on offer.
Comfort Inn & Suites Ankeny - Des Moines

Comfort Inn & Suites Ankeny - Des Moines

2.5 out of 5
215 Ne Delaware Ave, Ankeny, IA
Free Cancellation
Reserve now, pay when you stay
20.23 mi from Main Street Cultural District
$82 nightly
The price is $92 total per night
$92 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
Quality Inn & Suites Ankeny - Des Moines

Quality Inn & Suites Ankeny - Des Moines

2.5 out of 5
201 Se Delaware Ave, Ankeny, IA
Free Cancellation
Reserve now, pay when you stay
20.4 mi from Main Street Cultural District
$67 nightly
The price is $76 total per night
$76 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.
My Place Hotel - Ankeny/ Des Moines, IA

My Place Hotel - Ankeny/ Des Moines, IA

3 out of 5
2506 SE Tones Drive, Ankeny, IA
Free Cancellation
Reserve now, pay when you stay
22.22 mi from Main Street Cultural District
$80 nightly
The price is $90 total per night
$90 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the 24-hour business center and free internet in public areas. Free parking, a snack bar/deli, and a grocery/convenience store are also offered.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Main Street Cultural District hotels essential information

Accommodation
706 hotels
Lowest Price
$75
Highest Price
$122
Popular hotels
Gateway Hotel and Conference Center at Iowa State University, Country Inn & Suites by Radisson, Ames, IA, Comfort Inn and Suites Ames near ISU Campus, GrandStay Hotel & Suites, SpringHill Suites by Marriott Ames, Best Western Plus University Park Inn & Suites, Microtel Inn & Suites by Wyndham Ames, Hilton Garden Inn Ames, Qube Hotel, Comfort Inn & Suites Ankeny - Des Moines, Quality Inn & Suites Ankeny - Des Moines, My Place Hotel - Ankeny/ Des Moines, IA

Recent Main Street Cultural District hotel reviews by fellow wanderers

Qube Hotel

Qube Hotel

5 out of 5
Posted 6 days ago
Travelocity Verified Review
"great hotel. clean. friendly and close to Des Moines and Ames"
A verified traveler stayed at Qube Hotel
Qube Hotel

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