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Tonight Feb 22 - Feb 23

This weekend Feb 28 - Mar 1

Next weekend Mar 6 - Mar 8

Most Frequently Booked Ladys Island Hotels

Price for 1 night 2 adults*

$110

Feb 24 - Feb 25

Per night/room

The Bird's Nest... The Best Rest is at The Nest

Beaufort, SC

Situated in Beaufort, this guesthouse is 0.9 mi (1.4 km) from Coosaw Island and within 9 mi (15 km) of John Mark Verdier House and Bay Street. Henry C. Chambers Waterfront Park and Thomas Hepworth House are also within 9 mi (15 km).

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Lady's Island Vacation Retreat

Beaufort, SC

A garden is available at this apartment.

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Beaulieu House at Cat Island

3.0 out of 5.0 3 Sheffield Court, Beaufort, SC

An outdoor pool, free self parking, and wedding services are featured at this bed & breakfast. Guests will appreciate free perks like full breakfast and WiFi in public areas. A terrace, a garden, and a lobby fireplace are also on offer.

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How much is a hotel room in Ladys Island?

Hotels in Ladys Island start at $110 per night. Prices and availability subject to change. Additional terms may apply.

Cheap Hotels in Ladys Island

Pack your bags—it’s time to embark on a getaway. Whether you’re craving a solo retreat or promising your family a vacation to remember, book one of the best hotels in Ladys Island. These hotels are located within easy access of the city’s hottest attractions and entertainment, so you won’t miss a beat while you’re in town. Spend the days exploring the local landmarks and the evenings getting to know the nightlife. After exploring the city from top to bottom, rest up at a hotel that speaks to you. Find the perfect place that matches your trip’s vibe, from a trendy boutique to family-friendly accommodations.

Allow us here at Travelocity to pair you with up Ladys Island hotels that suit your vacation preferences. Discover places with convenient on-site restaurants, around-the-clock service, and pools where your kids can make a splash. Some hotels may boast fitness rooms and spa services, while others feature game rooms and Wi-Fi access. To top it all off, you’ll score cheap hotels in Ladys Island that let you spend more on your activities and less on your lodging. Book and bundle your flight and hotel deals together today and save up to $537. It’s time to explore a new city, and break out of your routine.