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Top hotels in Greater South Side

Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $189 total per night from Mar 8 to Mar 9
$189 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy ...
Ambience is fun and eclectic, staff are helpful and nice, continental breakfast has a lot of variety, beds are comfortable, pillows soft and supportive, and the shower is wonderful. To top it off, the bathroom is had the most counter space I've ever had at a hotel and I LOVED it!!!

Reviewed on Mar 2, 2026

Opens in a new windowDes Lux Hotel
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $146 total per night from Apr 4 to Apr 5
$146 total
Apr 4 - Apr 5
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. WiFi in public areas is free. Valet parking, a business center, and a coffee shop are also ...
The staff was great, especially Morgan!

Reviewed on Mar 6, 2026

Opens in a new windowHotel Fort Des Moines, Curio Collection by Hilton
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $100 total per night from Mar 15 to Mar 16
$100 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Clean! Quiet! Affordable! Staff was amazing and they have Breakfast!

Reviewed on Mar 7, 2026

Opens in a new windowHome2 Suites by Hilton Des Moines at Drake University
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $118 total per night from Mar 29 to Mar 30
$118 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Free perks include continental breakfast, free self parking, and a roundtrip airport shuttle. You'll appreciate ...
clean room, the airport shuttle took awhile to arrive. after we called, the staff was nice and friendly

Reviewed on Mar 5, 2026

Opens in a new windowHampton Inn Des Moines-Airport
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $71 total per night from Mar 23 to Mar 24
$71 total
Mar 23 - Mar 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
Smelled bad, was not clean, hair in the beds, staff were not knowledgeable

Reviewed on Mar 6, 2026

Opens in a new windowDays Inn & Suites by Wyndham Des Moines Airport
Sonesta Simply Suites Des Moines

Sonesta Simply Suites Des Moines

2.5 out of 5
7625 Office Plaza Dr N West Des Moines IA
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $85 total per night from Apr 5 to Apr 6
$85 total
Apr 5 - Apr 6
Total with taxes and fees
A 24-hour gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. A terrace, a snack bar/deli, and a grocery/convenience ...
The place

Reviewed on Mar 3, 2026

Opens in a new windowSonesta Simply Suites Des Moines
Holiday Inn Des Moines-Airport/Conf Center by IHG

Holiday Inn Des Moines-Airport/Conf Center by IHG

3 out of 5
6111 Fleur Dr Des Moines IA
Fully refundable
$116 nightly
The price is $130 total per night from Apr 5 to Apr 6
$130 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like free self parking and a free airport shuttle. There's ...
Wonderful stay beautiful place Staff was sp helpful

Reviewed on Mar 1, 2026

Opens in a new windowHoliday Inn Des Moines-Airport/Conf Center by IHG
AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport

2.5 out of 5
1920 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $67 total per night from Mar 29 to Mar 30
$67 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free self parking, and a free airport shuttle. Traveling on business? Take advantage ...
Nice hotel thats close to the airport with shuttle service to take you to and from the airport.

Reviewed on Mar 6, 2026

Opens in a new windowAmericInn by Wyndham Des Moines Airport
Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport

2.5 out of 5
5231 Fleur Dr Des Moines IA
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $72 total per night from Mar 16 to Mar 17
$72 total
Mar 16 - Mar 17
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
Good and convenient. Everything good except the pillows

Reviewed on Mar 7, 2026

Opens in a new windowQuality Inn & Suites Des Moines Airport
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Greater South Side Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Greater South Side area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Greater South Side to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Greater South Side are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Greater South Side hotel reviews by fellow wanderers

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