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Top hotels in Greater South Side
Des Lux Hotel
800 Locust St Des Moines IA
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $189 total per night from Mar 22 to Mar 23
$189 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy ...
We love the Des Lux Hotel! Mary at the front desk welcomes us home each time we stay. Estela in the breakfast room is so kind, caring and attentive.
Reviewed on Mar 18, 2026
Hotel Fort Des Moines, Curio Collection by Hilton
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $146 total per night from Apr 4 to Apr 5
$146 total
Apr 4 - Apr 5
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
Excellent experience at Fort Des Moines. Clean, comfortable room. We loved the Speakeasy in the hotel bar. Would absolutely stay here again.
Reviewed on Mar 20, 2026
Wildwood Lodge
11431 Forest Ave Clive IA
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $92 total per night from Mar 29 to Mar 30
$92 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features an indoor pool and a gym. Enjoy the hot tub and free perks like full breakfast and free self parking. A business center, free WiFi in public ...
Front desk and kitchen staff were really kind and helpful. The facility was clean and family oriented. Love the fire pit and breakfast.
Reviewed on Mar 20, 2026
Home2 Suites by Hilton Des Moines at Drake University
2650 University Ave. Des Moines IA
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $100 total per night from Mar 29 to Mar 30
$100 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
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Reviewed on Mar 19, 2026
Hampton Inn Des Moines-Airport
5001 Fleur Dr Des Moines IA
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $127 total per night from Mar 29 to Mar 30
$127 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Free perks include continental breakfast, free self parking, and a roundtrip airport shuttle. You'll appreciate ...
Very much appreciate the close proximity and clean hotel to the airport!
Reviewed on Mar 17, 2026
Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $73 total per night from Mar 25 to Mar 26
$73 total
Mar 25 - Mar 26
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
Clean room. Friendly and helpful front desk lady, and housekeepers. Highly recommend
Reviewed on Mar 19, 2026
Holiday Inn Des Moines-Airport/Conf Center by IHG
6111 Fleur Dr Des Moines IA
Fully refundable
$103 nightly
The price is $115 total per night from Apr 5 to Apr 6
$115 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like free self parking and a free airport shuttle. There's ...
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Reviewed on Mar 18, 2026
AmericInn by Wyndham Des Moines Airport
1920 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $67 total per night from Mar 29 to Mar 30
$67 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free self parking, and a free airport shuttle. Traveling on business? Take advantage ...
Wasn a bad place for needing something last minute. The bed was a little hard but I loved looking out and seeing the place take off.
Reviewed on Mar 19, 2026
Quality Inn & Suites Des Moines Airport
5231 Fleur Dr Des Moines IA
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Mar 30 to Mar 31
$70 total
Mar 30 - Mar 31
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
THE STAFF IS RUDE THEY LIED ABOUT HOT TUB WORKING BUT WASN'T ...POOL TORE UP ALL AROUND...Day mgr is very rude...breakfast is so so
Reviewed on Mar 20, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Greater South Side Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Greater South Side area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Greater South Side to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Greater South Side are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Greater South Side hotel reviews by fellow wanderers
Hotel Fort Des Moines, Curio Collection by Hilton
5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"Excellent experience at Fort Des Moines. Clean, comfortable room. We loved the Speakeasy in the hotel bar. Would absolutely stay here again. "
A verified traveler stayed at Hotel Fort Des Moines, Curio Collection by Hilton
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